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Diabetic Cardiomyopathy and Cell Death: Focus on Metal-Mediated Cell Death
Cardiac myocyte death is an essential initiator of the pathogenesis and progression of various etiological cardiomyopathies, including diabetic...
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Aluminum-Induced Neural Cell Death
Aluminum (Al), an abundant element in the Earth’s crust, is well known for its neurotoxicity. Nonetheless, its causal role in neurodegenerative... -
Cell death by phagocytosis
Cells can die as a consequence of being phagocytosed by other cells — a form of cell death that has been called phagotrophy, cell cannibalism,...
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Neuronal Cell Death Methods and Protocols
This volume covers comprehensive methods on ways to assess structural and ultrastructural changes in the mitochondria, cytoskeleton, and microglia...
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Cell Death-NO-Today: Effect of NO and RNS on Non-apoptotic Regulated Cell Death
Nitric oxide (NO), generated either enzymatically or non-enzymatically plays a significant role in cellular physiology. At low concentration, NO acts... -
A matter of new life and cell death: programmed cell death in the mammalian ovary
BackgroundThe mammalian ovary is a unique organ that displays a distinctive feature of cyclic changes throughout the entire reproductive period. The...
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Disulfidptosis: A new type of cell death
Disulfidptosis is a novel form of cell death that is distinguishable from established programmed cell death pathways such as apoptosis, pyroptosis,...
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Cell Death and Replicative Senescence in Cancer
For continuous growth, cancer cells must overcome barriers posed by terminal differentiation, replicative senescence, and cell death by apoptosis.... -
Diversity and complexity of cell death: a historical review
Death is the inevitable fate of all living organisms, whether at the individual or cellular level. For a long time, cell death was believed to be an...
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Entosis: the core mechanism and crosstalk with other cell death programs
Cell death pathways play critical roles in organism development and homeostasis as well as in the pathogenesis of various diseases. While studies...
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Death-associated protein 3 in cell death and beyond
Death-associated protein 3 (DAP3) is a highly conserved guanosine triphosphate (GTP) binding protein. As a component of the mitochondrial ribosome...
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Targeting immunogenic cell stress and death for cancer therapy
Immunogenic cell death (ICD), which results from insufficient cellular adaptation to specific stressors, occupies a central position in the...
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Crosstalk between metabolism and cell death in tumorigenesis
It is generally recognized that tumor cells proliferate more rapidly than normal cells. Due to such an abnormally rapid proliferation rate, cancer...
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The therapeutic potential of targeting regulated non-apoptotic cell death
Cell death is critical for the development and homeostasis of almost all multicellular organisms. Moreover, its dysregulation leads to diverse...
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The significant mechanism and treatments of cell death in heatstroke
With global warming, extreme environmental heat is becoming a social issue of concern, which can cause adverse health results including heatstroke...
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Crosstalk Between Cell Death and Spinal Cord Injury: Neurology and Therapy
Spinal cord injury (SCI) often leads to neurological dysfunction, and neuronal cell death is one of the main causes of neurological dysfunction....