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Longitudinal follow-up of zearalenone and deoxynivalenol mycotoxins in breast milk in the first five months of life
ObjectivesThere is a possibility for exposed lactating mammalians to transfer some contaminants to their milk. This study aimed to determine the...
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Fluorescence Sensor for Zearalenone Detection Based on Oxidized Single-walled Carbon Nanohorns/N-doped Carbon Quantum Dots-aptamer
Zearalenone (ZEN), a resorcinolactone toxin, which has been a potential threat to agricultural production and human health. In this study, a sample...
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Zearalenone disturbs the reproductive-immune axis in pigs: the role of gut microbial metabolites
BackgroundExposure to zearalenone (ZEN, a widespread Fusarium mycotoxin) causes reproductive toxicity and immunotoxicity in farm animals, and it...
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Influence of deoxynivalenol and zearalenone on the immunohistochemical expression of oestrogen receptors and liver enzyme genes in vivo in prepubertal gilts
Deoxynivalenol (DON) and zearalenone (ZEN) are often detected in plant materials used to produce feed for pre-pubertal gilts. Daily exposure to small...
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Estrogenic in vitro evaluation of zearalenone and its phase I and II metabolites in combination with soy isoflavones
Humans and animals are exposed to multiple substances in their food and feed that might have a negative health impact. Among these substances, the Fusarium...
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Mycotoxin Quantification by Competitive ELISA
Enzyme-linked immunosorbent assays (ELISAs) are useful in the quantification of antigens like mycotoxins. The zearalenone (ZEA) mycotoxin is commonly...
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Rapid and simultaneous purification of aflatoxin B1, zearalenone and deoxynivalenol using their monoclonal antibodies and magnetic nanoparticles
To develop a new simple and simultaneous purification method for mycotoxins in feeds and grains, magnetic nanoparticles (MNPs) conjugated with...
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Role of ferroptosis in food-borne mycotoxin-induced toxicities
Contamination by toxic substances is a major global food safety issue, which poses a serious threat to human health. Mycotoxins are major class of...
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PCR-Based Detection and Quantification of Mycotoxin-Producing Fungi
AbstractOne of the main factors reducing the quality of agricultural products can be contamination with molds capable of producing mycotoxins that...
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Cytotoxic and inflammatory effects of individual and combined exposure of HepG2 cells to zearalenone and its metabolites
Zearalenone (ZEA), a mycotoxin produced by several Fusarium spp., is most commonly found as a contaminant in stored grain. ZEA derivatives...
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Assessment of multiple mycotoxin exposure and its association with food consumption: a human biomonitoring study in a pregnant cohort in rural Bangladesh
Aflatoxins (AFs), ochratoxin A (OTA), citrinin (CIT), fumonisin B 1 (FB 1 ), zearalenone (ZEN), and deoxynivalenol (DON) are mycotoxins that may...
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Metabolic profiling as a powerful tool for the analysis of cellular alterations caused by 20 mycotoxins in HepG2 cells
Mycotoxins are secondary fungal metabolites which exhibit toxic effects in low concentrations. Several mycotoxins are described as carcinogenic or...
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Structure-based virtual screening of CYP1A1 inhibitors: towards rapid tier-one assessment of potential developmental toxicants
Cytochrome P450 1A1 (CYP1A1) metabolizes estrogens, melatonin, and other key endogenous signaling molecules critical for embryonic/fetal development....
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Biomarkers for Assessing Mycotoxin Exposure and Health Effects
A variety of adverse health effects can be determined after exposure to mycotoxins, the toxic metabolites produced by some fungi species during...
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Deglucosylation of zearalenone-14-glucoside in animals and human liver leads to underestimation of exposure to zearalenone in humans
Zearalenone-14-glucoside (ZEN-14G), the modified mycotoxin of zearalenone (ZEN), has attracted considerable attention due to its high potential to be...
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Dual flow immunochromatographic assay for rapid and simultaneous quantitative detection of ochratoxin A and zearalenone in corn, wheat, and feed samples
A one-step dual flow immunochromatographic assay (DICGA), based on a competitive format, was developed for simultaneous quantification of ochratoxin...
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Toxins in Millets
Mycotoxins are an emerging threat to humans, mainly through microbial infected food. Though millets are versatile crops, during the unit operation...
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Application of Biotechnology in Pharmaceutical Manufacturing Control
Pharmaceutical biotechnology represents a rapidly evolving field wherein biotechnological principles are applied to diverse pharmaceutical...