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Introduction to West Nile Virus
West Nile virus (WNV) is a mosquito-borne, single-stranded, positive-sense RNA virus belonging to the Flaviviridae family. After WNV gains entry...
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Phylogenetic analysis and molecular genetic characteristics of West Nile virus lineage 2 isolates circulating in the Russian Federation
Since its initial detection in Africa, the West Nile virus has disseminated widely across all continents, becoming endemic in numerous countries,...
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Cellular co-infections of West Nile virus and Usutu virus influence virus growth kinetics
The mosquito-borne flaviviruses West Nile virus (WNV) and Usutu virus (USUV) pose a significant threat to the health of humans and animals. Both...
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Development of Antibody-Based Therapeutics Against West Nile Virus in Plants
Since its discovery in 1937 in the West Nile district of Uganda, West Nile virus (WNVWest Nile virus (WNV)) has been one of the leading causes of...
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A chimeric vaccine protects farmed saltwater crocodiles from West Nile virus-induced skin lesions
West Nile virus (WNV) causes skin lesions in farmed crocodiles leading to the depreciation of the value of their hides and significant economic...
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Viral Titer Quantification of West Nile Virus by Immunostaining Plaque Assay
Immunostained plaque assay based on the specific antibody binding to viral antigen enables the detection and titration of virus infectivity,...
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Higher replication potential of West Nile virus governs apoptosis induction in human neuroblastoma cells
The extent of neuronal cell damage caused by West Nile virus (WNV) infection governs the disease severity ranging from mild, febrile illness to fatal...
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West Nile Virus: From Africa to Europe, America, and Beyond
Since the mid-1990s, West Nile virus (WNV) outbreaks of increased severity first appeared in Africa, then in Europe, and finally in North America....
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Detection of disease-associated microglia among various microglia phenotypes induced by West Nile virus infection in mice
West Nile virus (WNV) has emerged as a significant cause of viral encephalitis in humans and horses. However, the pathogenesis of the West Nile...
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Glycolytic shift during West Nile virus infection provides new therapeutic opportunities
BackgroundViral rewiring of host bioenergetics and immunometabolism may provide novel targets for therapeutic interventions against viral infections....
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Detection of West Nile Virus Envelope Protein in Brain Tissue with an Immunohistochemical Assay
Immunohistochemistry is a valuable tool for probing not only scientific questions but also clinical diagnoses. It provides power from localization of...
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Human biting mosquitoes and implications for West Nile virus transmission
BackgroundWest Nile virus (WNV), primarily vectored by mosquitoes of the genus Culex , is the most important mosquito-borne pathogen in North...
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Influence of Biological Model on the Formation of the Pathogenic Properties of the West Nile Virus Isolate
Various biological models are used to isolate West Nile virus, but their role as a selection factor that facilitates selection of isolates with...
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West Nile Virus: From Africa to Europe, America, and Beyond
Since the mid-1990s, West Nile virus (WNV) outbreaks of increased severity first appeared in Africa, then in Europe, and finally in North America....
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West Nile Virus
Since its introduction to North America in 1999, West Nile virus (WNV) has established itself as an endemic pathogen with regular seasonal outbreaks....
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Sensitivity of Quails (Coturnix coturnix), Siskins (Carduelis spinus), and Frogs (Rana ridibunda) to West Nile Virus
The level of viremia and features of the course of experimental infection caused by West Nile virus were studied in two species of migratory birds,...
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Identification of the flavivirus conserved residues in the envelope protein hinge region for the rational design of a candidate West Nile live-attenuated vaccine
The flavivirus envelope protein is a class II fusion protein that drives flavivirus-cell membrane fusion. The membrane fusion process is triggered by...
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West Nile
West Nile is a neurotropic problem caused by West Nile virus (WNV), a neurotropic arbovirus. The natural reservoir and biological vector of the WNV...
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Isolation of Exosomes or Extracellular Vesicles from West Nile Virus-Infected N2a Cells, Primary Cortical Neurons, and Brain Tissues
Several flaviviruses compromise the blood-brain barrier integrity, infect the central nervous system, and elicit neuroinvasion to successfully cause...
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Recovery and Genetic Characterization of a West Nile Virus Isolate from China
West Nile virus (WNV) is an important neurotropic flavivirus that is widely distributed globally. WNV strain XJ11129 was first isolated in **njiang,...
