Search
Search Results
-
Viral RNA Is a Hub for Critical Host–Virus Interactions
RNA is a central molecule in the life cycle of viruses, acting not only as messenger (m)RNA but also as a genome. Given these critical roles, it is...
-
DEAD box RNA helicase 5 is a new pro-viral host factor for Sindbis virus infection
BackgroundRNA helicases are emerging as key factors regulating host-virus interactions. The DEAD-box ATP-dependent RNA helicase DDX5, which plays an...
-
Dengue virus pathogenesis and host molecular machineries
Dengue viruses (DENV) are positive-stranded RNA viruses belonging to the Flaviviridae family. DENV is the causative agent of dengue, the most rapidly...
-
Comparative analysis of retroviral Gag-host cell interactions: focus on the nuclear interactome
Retroviruses exploit host proteins to assemble and release virions from infected cells. Previously, most studies focused on interacting partners of...
-
Isolation and Identification of Dengue Virus Interactome with Human Plasma Proteins by Affinity Purification-Mass Spectrometry
Viral proteins evolve to benefit the interaction with host proteins during the infection and replication processes. A comprehensive understanding of...
-
YWHAH, a member of 14-3-3 family proteins, and PSME2, the proteasome activator subunit 2, are key host factors of Japanese encephalitis virus infection
BackgroundHost response to virus infection is key to the effective control and eventual elimination of viruses or infected cells; however, the...
-
Plant-Virus Interactions
This detailed volume provides practical guidance on techniques in plant-virus interaction research, from targeting specific molecular interactions...
-
Immunoprecipitation Followed by Mass Spectrometry: An Approach for Identifying Host–Viral Protein–Protein Interactions
As obligate intracellular parasites, viruses rely on the efficient manipulation of the cell they invade in order to multiply and spread....
-
4C Analysis of EBV-Host DNA Interactome
EBV persist as multicopy episomes in latently infected cells and alter transcriptional program of host systems. Knowledge of EBV tethering site helps...
-
In Situ Protein Microarray for Identifying the Geminivirus–Arabidopsis Interactome
The protein–protein interactions (PPI) by protein array technology complement other PPI assay technologies such as AP-MS and Y2H. The in situ protein...
-
Anti-Influenza Drug Discovery and Development: Targeting the Virus and Its Host by All Possible Means
Infections by influenza virus constitute a major and recurrent threat for human health. Together with vaccines, antiviral drugs play a key role in...
-
-
Decoding protein–RNA interactions using CLIP-based methodologies
Protein–RNA interactions are central to all RNA processing events, with pivotal roles in the regulation of gene expression and cellular functions....
-
Biomolecular condensates: insights into early and late steps of the HIV-1 replication cycle
A rapidly evolving understanding of phase separation in the biological and physical sciences has led to the redefining of virus-engineered...
-
COVID-19: viral–host interactome analyzed by network based-approach model to study pathogenesis of SARS-CoV-2 infection
BackgroundEpidemiological, virological and pathogenetic characteristics of SARS-CoV-2 infection are under evaluation. A better understanding of the...
-
Mechanisms and consequences of mRNA destabilization during viral infections
During viral infection there is dynamic interplay between the virus and the host to regulate gene expression. In many cases, the host induces the...
-
Japanese Encephalitis Virus-Infected Cells
RNA virus infections have been a leading cause of pandemics. Aided by global warming and increased connectivity, their threat is likely to increase...
-
A Machine Learning Approach to Identify Potential miRNA-Gene Regulatory Network Contributing to the Pathogenesis of SARS-CoV-2 Infection
Worldwide, many lives have been lost in the recent outbreak of coronavirus disease. The pathogen responsible for this disease takes advantage of the...
-
In silico analysis of cloned brown planthopper genes unveiled OsJ_28113 as a key regulator in triggering resistance response in rice
Brown planthopper (BPH) is a highly destructive insect pest of rice, causing significant yield loss. Due to its constantly evolving nature,...
-
Network medicine links SARS-CoV-2/COVID-19 infection to brain microvascular injury and neuroinflammation in dementia-like cognitive impairment
BackgroundDementia-like cognitive impairment is an increasingly reported complication of SARS-CoV-2 infection. However, the underlying mechanisms...
