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15 weeks of soccer training increases left ventricular mass and improves indices of left ventricular diastolic function in previously sedentary, mildly hypertensive, middle-aged women
PurposeTo investigate the impact of soccer training on cardiac adaptations in mildly hypertensive middle-aged women.
MethodsHypertensive...
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Human Genetics of Ventricular Septal Defect
Ventricular septal defects (VSDs) are recognized as one of the commonest congenital heart diseases (CHD), accounting for up to 40% of all cardiac...
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Origin of congenital coronary arterio-ventricular fistulae from anomalous epicardial and myocardial development
Coronary Artery Fistulae (CAFs) are cardiac congenital anomalies consisting of an abnormal communication of a coronary artery with either a cardiac...
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Defining left ventricular remodeling using lean body mass allometry: a UK Biobank study
PurposeThe geometric patterns of ventricular remodeling are determined using indexed left ventricular mass (LVM), end-diastolic volume (LVEDV) and...
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Trans-aortic Valvular Ejection Fraction for Monitoring Recovery of Patients with Ventricular Systolic Heart Failure
Durable mechanical circulatory support in the form of left ventricular (LV) assist device (LVAD) therapy is increasingly considered in the context of...
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Local decorin delivery via hyaluronic acid microrods improves cardiac performance, ventricular remodeling after myocardial infarction
Heart failure (HF) remains a global public health burden and often results following myocardial infarction (MI). Following injury, cardiac fibrosis...
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Biventricular Interaction During Acute Left Ventricular Ischemia in Mice: A Combined In-Vivo and In-Silico Approach
Computational models provide an efficient paradigm for integrating and linking multiple spatial and temporal scales. However, these models are...
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Acausal Modelling of Advanced-Stage Heart Failure and the Istanbul Heart Ventricular Assist Device Support with Patient Data
BackgroundIn object-oriented or acausal modelling, components of the model can be connected topologically, following the inherent structure of the...
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Interactions of Stress, Psychology, and Cardiovascular Function
Stress is a construct that may be nearly universally understood, discussed at length among scientists and in casual conversation. Stressors, which...
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Optimization of the Parameters of Ventricular Assist Devices Using Computerized Mathematical Modeling of the Cardiovascular System
The construction of secondary mathematical models for optimizing the parameters of nonpulsatile flow pumps (NPFP) for ventricular assistance is...
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Identification and functional analysis of variants of MYH6 gene promoter in isolated ventricular septal defects
BackgroundVentricular septal defect is the most common form of congenital heart diseases. MYH6 gene has a critical effect on the growth and...
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A History of Immune and Neuroendocrine System Interactions
The purpose of this chapter is to provide a twentieth century history of neuroendocrine and immune systems and the interactions of their components....
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The impact of Alzheimer's disease susceptibility loci on lateral ventricular surface morphology in older adults
The enlargement of ventricular volume is a general trend in the elderly, especially in patients with Alzheimer’s disease (AD). Multiple...
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Biomarker Determinants of Early Anthracycline-Induced Left Ventricular Dysfunction in Breast Cancer: A Systematic Review and Meta-Analysis
Background and ObjectiveBreast cancer is the leading cause of cancer-related mortality amongst women. One of the most common chemotherapeutic agents...
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Antagonistic Herb-Drug Interactions
According to WHO drug strategy survey, majority of the population in both develo** and developed countries use herbal medicines leading to chances...
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A Mechanistic Lumped Parameter Model of the Berlin Heart EXCOR to Analyze Device Performance and Physiologic Interactions
PurposeThe Berlin Heart EXCOR (BH) is the only FDA-approved, extracorporeal pulsatile ventricular assist device (VAD) for infants and children with...
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Quantitative Assessment of Aortic Hemodynamics for Varying Left Ventricular Assist Device Outflow Graft Angles and Flow Pulsation
Left ventricular assist devices (LVADs) comprise a primary treatment choice for advanced heart failure patients. Treatment with LVAD is commonly...
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Z16b, a natural compound from Ganoderma cochlear is a novel RyR2 stabilizer preventing catecholaminergic polymorphic ventricular tachycardia
Catecholaminergic polymorphic ventricular tachycardia (CPVT) is an inherited, lethal ventricular arrhythmia triggered by catecholamines. Mutations in...
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Simulation of drug-drug interactions between breast cancer chemotherapeutic agents and antiemetic drugs
BackgroundChemotherapy-induced nausea and vomiting are commonly experienced side effects in breast cancer (BCa) patients. Antiemetic drugs used in...
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Effect of left ventricular assist device on the hemodynamics of a patient-specific left heart
This article describes the numerical efforts made to investigate the influence of a left ventricular assist device (LVAD) on the patient-specific...
