Search
Search Results
-
Explainable artificial intelligence for the automated assessment of the retinal vascular tortuosity
AbstractRetinal vascular tortuosity is an excessive bending and twisting of the blood vessels in the retina that is associated with numerous health...
-
3D Visualization of Whole Brain Vessels and Quantification of Vascular Pathology in a Chronic Hypoperfusion Model Causing White Matter Damage
Chronic cerebral hypoperfusion is an important pathological factor in many neurodegenerative diseases, such as cerebral small vessel disease (CSVD)....
-
Vascular Diseases
This group of diseases is caused by defects in the blood supply. Brain cells are only affected secondarily. In ischemic stroke, all cells die in the...
-
A neuropathologic feature of brain aging: multi-lumen vascular profiles
Cerebrovascular pathologies other than frank infarctions are commonly seen in aged brains. Here, we focus on multi-lumen vascular profiles (MVPs),...
-
Vascular and Degenerative Retinal Diseases
The retina, consisting of ten layers, is the innermost tissue of the eye and serves to capture light stimuli from the outside, transforming them into...
-
Late chronic local inflammation, synaptic alterations, vascular remodeling and arteriovenous malformations in the brains of male rats exposed to repetitive low-level blast overpressures
In the course of military operations in modern war theaters, blast exposures are associated with the development of a variety of mental health...
-
Pathophysiology and probable etiology of cerebral small vessel disease in vascular dementia and Alzheimer’s disease
Vascular cognitive impairment and dementia (VCID) is commonly caused by vascular injuries in cerebral large and small vessels and is a key driver of...
-
Application of fluorescence micro-optical sectioning tomography in the cerebrovasculature and applicable vascular labeling methods
Fluorescence micro-optical sectioning tomography (fMOST) is a three-dimensional (3d) imaging method at the mesoscopic level. The whole-brain of mice...
-
Low-level blast exposure induces chronic vascular remodeling, perivascular astrocytic degeneration and vascular-associated neuroinflammation
Cerebral vascular injury as a consequence of blast-induced traumatic brain injury is primarily the result of blast wave-induced mechanical...
-
Roles of peripheral lipoproteins and cholesteryl ester transfer protein in the vascular contributions to cognitive impairment and dementia
This narrative review focuses on the role of cholesteryl ester transfer protein (CETP) and peripheral lipoproteins in the vascular contributions to...
-
Loss of Direct Vascular Contact to Astrocytes in the Hippocampus as an Initial Event in Alzheimer’s Disease. Evidence from Patients, In Vivo and In Vitro Experimental Models
Alzheimer’s disease (AD) is characterized by the accumulation of aggregated amyloid peptides in the brain parenchyma and within the walls of cerebral...
-
Increased vascular smooth muscle cell senescence in aneurysmal Fibulin-4 mutant mice
Aortic aneurysms are dilatations of the aorta that can rupture when left untreated. We used the aneurysmal Fibulin-4 R/R mouse model to further...
-
Correlation between LOX-1 and CX3CR1 and Vascular Endothelial Function, Fibrinolytic Activity, and Recurrence after Thrombolysis in Patients with Cerebral Infarction
AbstractThis study analyzed the relationship between LOX-1 and CX3CR1 and vascular endothelial function, fibrinolytic activity, and recurrence rate...
-
Imaging Vascular Anatomy and Pathology of the Posterior Fossa
Neurovascular diseases of the posterior circulation represent a major cause of morbidity and mortality, which is due in large part to the eloquence...
-
Central nervous system anomalies in 41 Chinese children incontinentia pigmenti
IntroductionIncontinentia pigmenti (IP) is a rare neuroectodermal dysplasia caused by a defect in the IKBKG gene. The pathogenesis of central...
-
Hemangioblastomas and Other Vascular Origating Tumors of Brain or Spinal Cord
HemangioblastomasHemangioblastomas (HBs) are highly vascularized, slow-growing, rare benignBenign tumors (WHO gradeWHO grade I). They account for...
-
Experimental Protocol and Phantom Design and Development for Performance Characterization of Conventional Devices for Peripheral Vascular Interventions
Conventional catheter-based interventions for treating peripheral artery disease suffer high failure and complication rates. The mechanical...
-
Hemodynamics and Vascular Remodeling
The flow of blood in the vasculature generates forces that act on vessel walls. Blood pressure generates circumferential stresses within the walls,...
-
Complement C3a Receptor (C3aR) Mediates Vascular Dysfunction, Hippocampal Pathology, and Cognitive Impairment in a Mouse Model of VCID
Vascular contributions to cognitive impairment and dementia (VCID) secondary to chronic mild-moderate cerebral ischemia underlie a significant...
-
Tumour irradiation combined with vascular-targeted photodynamic therapy enhances antitumour effects in pre-clinical prostate cancer
BackgroundThere is a need to improve the treatment of prostate cancer (PCa) and reduce treatment side effects. Vascular-targeted photodynamic therapy...
