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GM-CSF Promotes the Development of Dysfunctional Vascular Networks in Moyamoya Disease
Moyamoya disease (MMD) is a chronic occlusive cerebrovascular disease with the development of a network of abnormal vessels. Immune inflammation is...
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Detection of Possible Symmetries in Vascular Networks by Computer-Assisted Image Analysis
The possible forms that vascular networks may assume are significantly constrained by complex demands in terms of efficient delivery of oxygen and...
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The in vitro dynamics of pseudo-vascular network formation
Background/ObjectivesPseudo-vascular network formation in vitro is considered a key characteristic of vasculogenic mimicry. While many cancer cell...
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Chronic social defeat alters brain vascular-associated cell gene expression patterns leading to vascular dysfunction and immune system activation
Brain vascular integrity is critical for brain health, and its disruption is implicated in many brain pathologies, including psychiatric disorders....
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Vascular Diseases
This group of diseases is caused by defects in the blood supply. Brain cells are only affected secondarily. In ischemic stroke, all cells die in the...
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Explainable artificial intelligence for the automated assessment of the retinal vascular tortuosity
AbstractRetinal vascular tortuosity is an excessive bending and twisting of the blood vessels in the retina that is associated with numerous health...
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Cadmium, von Willebrand factor and vascular aging
Vascular aging is a major contributing factor to cardiovascular disease. The aged blood vessels, characterized by vascular wall thickening and...
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Vascular mimicry in zebrafish fin regeneration: how macrophages build new blood vessels
Vascular mimicry has been thoroughly investigated in tumor angiogenesis. In this study, we demonstrate for the first time that a process closely...
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Implications of vascular depression for successful cognitive aging in HIV Disease
Although older adults with HIV are at high risk for mild neurocognitive disorders, a subset experience successful cognitive aging (SCA). HIV is...
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Cuproptosis and copper deficiency in ischemic vascular injury and repair
Ischemic vascular diseases are on the rise globally, including ischemic heart diseases, ischemic cerebrovascular diseases, and ischemic peripheral...
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Advanced Computational Methods to Evaluate Vascular Heterogeneity in Tumor Tissue Based on Single Plane Illumination Microscopy
During tumor growth, the complex composition of vasculature is prone to dynamic changes due to mechanic and biochemical challenges. Perivascular...
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Vascular Endothelium
The endothelium is strategically located at the interface between the blood flow and the vascular smooth muscle and other components of the vessel...
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Revealing the Modular Similarities and Differences Among Alzheimer’s Disease, Vascular Dementia, and Parkinson’s Disease in Genomic Networks
Alzheimer’s disease (AD), vascular dementia (VD), and Parkinson’s disease (PD) exert increasingly lethal or disabling effects on humans, but the...
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What’s the Future of Vascular Neurology?
The field of vascular neurology has made tremendous advances over the last several decades, with major shifts in diagnosis, treatment, prevention,...
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Application of fluorescence micro-optical sectioning tomography in the cerebrovasculature and applicable vascular labeling methods
Fluorescence micro-optical sectioning tomography (fMOST) is a three-dimensional (3d) imaging method at the mesoscopic level. The whole-brain of mice...
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Development of vascular disease models to explore disease causation and pathomechanisms of rare vascular diseases
As the field of medicine is striving forward heralded by a new era of next-generation sequencing (NGS) and integrated technologies such as...
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Endothelial cell expression of mutant Map2k1 causes vascular malformations in mice
Extracranial arteriovenous malformation (AVM) is a congenital vascular anomaly causing disfigurement, bleeding, ulceration, and pain. Most lesions...
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Functional abnormalities of the cerebellum in vascular mild cognitive impairment
ObjectivesThe alterations in cerebellar activity that occur in vascular mild cognitive impairment remain largely unexplored. This study aimed to...
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Pathophysiology and probable etiology of cerebral small vessel disease in vascular dementia and Alzheimer’s disease
Vascular cognitive impairment and dementia (VCID) is commonly caused by vascular injuries in cerebral large and small vessels and is a key driver of...
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Electroencephalography-Derived Functional Connectivity in Sensorimotor Networks in Post Stroke Fatigue
BackgroundPoor suppression of anticipated sensory information from muscle contractions is thought to underlie high fatigue. Such diminished...
