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The urgency for a change in genetics healthcare provision: views from Portuguese medical geneticists
In the last decades, genetics has experienced significant technological advancements worldwide. However, in Portugal, serious limitations persist,...
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Urgency and necessity of Epstein-Barr virus prophylactic vaccines
Epstein-Barr virus (EBV), a γ-herpesvirus, is the first identified oncogenic virus, which establishes permanent infection in humans. EBV causes...
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Consistent evidence of indirect effects of impulsive delay discounting and negative urgency between childhood adversity and adult substance use in two samples
RationaleExposure to adverse life experiences (ACEs) is robustly associated with problematic alcohol and other drug use. In addition, both ACEs and...
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Impulsivity, emotional disorders and cognitive distortions in the general population: highlighting general interaction profiles
Cognitive distortions, defined as erroneous information-processing, are involved in the emergence and maintenance of various mental and emotional...
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Relationship of negative urgency to cingulo-insular and cortico-striatal resting state functional connectivity in tobacco use
Negative urgency, defined as a tendency to act rashly under extreme negative emotion, is strongly associated with tobacco use. Despite the robust...
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Correction to: The urgency of utilizing COVID-19 biospecimens for research in the heart of the global pandemic
An amendment to this paper has been published and can be accessed via the original article.
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The urgency of utilizing COVID-19 biospecimens for research in the heart of the global pandemic
The outbreak of the novel coronavirus disease 2019 (COVID-19) and consequent social distancing practices have disrupted essential clinical research...
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Development of a well-defined tool to predict the overall survival in lung cancer patients: an African based cohort
BackgroundNomogram is a graphic representation containing the expressed factor of the mathematical formula used to define a particular phenomenon. We...
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Noninvasive spinal neuromodulation mitigates symptoms of idiopathic overactive bladder
BackgroundOveractive bladder (OAB) affects 12 to 30% of the world’s population. The accompanying urinary urgency, frequency and incontinence can have...
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Botulinum Toxin Treatment of Bladder and Pelvic Disorders
Botulinum toxins blocks the release of neurotransmitters at nerve-muscle junction. Neurotransmitters are chemicals that convey the message of the... -
A randomized controlled trial evaluating low-intensity shockwave therapy for treatment of persistent storage symptoms following transurethral surgery for benign prostatic obstruction
BackgroundLow-intensity shockwave therapy (Li-SWT) can improve bladder function through enhancement of angiogenesis and nerve regeneration and...
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Neurological aspects of HTLV-1 infection: symptoms in apparently asymptomatic carriers
Human T-lymphotropic virus type 1 (HTLV-1) is classically associated with the HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP),...
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Somatic Gene Therapy Research in Pediatric Populations: Ethical Issues and Guidance for Operationalizing Early Phase Trials
Currently, pediatric research involving investigational gene therapies (GT, used without intending to imply a therapeutic effect) targets a broad...
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Healthcare on the brink: navigating the challenges of an aging society in the United States
The US healthcare system is at a crossroads. With an aging population requiring more care and a strained system facing workforce shortages, capacity...
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Hereditary spastic paraplegia in Mali: epidemiological and clinical features
Background and purposeHereditary spastic paraplegia (HSP) is a group of neurodegenerative diseases divided into pure and complex forms, with...
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Factors influencing fever care-seeking for children under five years of age in The Gambia: a secondary analysis of 2019–20 DHS data
BackgroundMalaria contributes to excess child mortality in The Gambia. Children under five are at risk of severe malaria and death if not treated...
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The Role of the Neural Exposome as a Novel Strategy to Identify and Mitigate Health Inequities in Alzheimer’s Disease and Related Dementias
With the continuous increase of the elderly population, there is an urgency to understand and develop relevant treatments for Alzheimer’s disease and...
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Conclusion
In face of the ongoing pandemic, heroic efforts have been made to develop Covid-19 vaccines, including those that utilize new technology with no... -
User Engagement on a Novel Educational Health Intervention Aimed at Increasing HPV Vaccine Uptake in Hong Kong: a Qualitative Study
HPV vaccine uptake rates are suboptimal in Hong Kong. A multi-disciplinary school-based HPV health-promotion programme (MDL-SHPVP) aimed at raising...
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Effects of Social Isolation on Perineuronal Nets in the Amygdala Following a Reward Omission Task in Female Rats
Negative urgency is a facet of impulsivity associated with negative affect and risky behavior that may involve the amygdala. The current study...