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Rest Tremor
By definition, rest tremor is an involuntary oscillation occurring while the body segment is maintained at rest, fully supported against gravity. To...
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Two Origins of Tremors Related to the Guillain-Mollaret Triangle: The Forward Model-Related Tremor and the Inferior Olive Oscillation-Related Tremor
Lesions in the Guillain-Mollaret (G-M) triangle frequently cause various types of tremors. Nevertheless, we know relatively little about their...
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Definition of Tremor
Tremor is generally defined as a rhythmic shaking of a body part (Deuschl et al., Ad Hoc Scientific Committee Mov Disord 13(suppl 3):2–23, 1998;...
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Dystonic Tremor
We review here the development and usage of the expression “dystonic tremor” and put it into perspective with controversies in the clinical setting....
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Membrane Mechanisms of Tremor
Tremor is one of the most common hyperkinetic movement disorders. Tremors can be of many different types, and the etiopathogenesis is very diverse...
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Identifying and modulating distinct tremor states through peripheral nerve stimulation in Parkinsonian rest tremor
BackgroundResting tremor is one of the most common symptoms of Parkinson’s disease. Despite its high prevalence, resting tremor may not be as...
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Mental calculation increases physiological postural tremor, but does not influence physiological goal-directed kinetic tremor
PurposeDuring a cognitive effort, an increase in cortical electrical activity, functional alterations in the anterior cingulate cortex, and...
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Deep Brain Stimulation for Tremor
Tremor is one of the most frequent complaints in the movement disorder clinic. Not only it can be encountered in multiple different syndromes, but it...
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The Role of Cerebellum and Basal Ganglia Functional Connectivity in Altered Voluntary Movement Execution in Essential Tremor
Substantial evidence highlights the role of the cerebellum in the pathophysiology of tremor in essential tremor (ET), although its potential...
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A review on pathology, mechanism, and therapy for cerebellum and tremor in Parkinson’s disease
Tremor is one of the core symptoms of Parkinson’s disease (PD), but its mechanism is poorly understood. The cerebellum is a growing focus in...
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Treatment of Involuntary Movements (Dystonia, Tremor, Tic)
Botulinum toxins, after injection into the muscle, block the release of acetylcholine from the neuromuscular junction. Acetylcholine is a chemical...
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Hyperventilation Increases the Randomness of Ocular Palatal Tremor Waveforms
Hyperventilation changes the extracellular pH modulating many central pathologies, such as tremor. The questions that remain unanswered are the...
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Pallidal Activity in Cervical Dystonia with and Without Head Tremor
The relationship between two common movement disorders, dystonia and tremor, is controversial. Both deficits have correlates in the network that...
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Increased Purkinje Cell Complex Spike and Deep Cerebellar Nucleus Synchrony as a Potential Basis for Syndromic Essential Tremor. A Review and Synthesis of the Literature
We review advances in understanding Purkinje cell (PC) complex spike (CS) physiology that suggest increased CS synchrony underlies syndromic...
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Gabapentin and memantine increases randomness of oscillatory waveform in ocular palatal tremor
Syndrome of oculopalatal tremor (OPT) causes pendular nystagmus of the eyes and its disabling consequence on the visual system. Classic...
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The theoretical mechanism of Parkinson’s oscillation frequency bands: a computational model study
Excessive synchronous oscillation activities appear in the brain is a key pathological feature of Parkinson’s disease, the mechanism of which is...
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Exploring the effects of deep brain stimulation and vision on tremor in Parkinson’s disease - benefits from objective methods
BackgroundTremor is a cardinal symptom of Parkinson’s disease (PD) that may cause severe disability. As such, objective methods to determine the...
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Impaired Saccade Adaptation in Tremor-Dominant Cervical Dystonia—Evidence for Maladaptive Cerebellum
We examined the role of the cerebellum in patients with tremor-dominant cervical dystonia by measuring the adaptive capacity of rapid reflexive eye...
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Physiological Recordings of the Cerebellum in Movement Disorders
The cerebellum plays an important role in movement disorders, specifically in symptoms of ataxia, tremor, and dystonia. Understanding the...
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Pendular Oscillation and Ocular Bobbing After Pontine Hemorrhage
The pathophysiology of acute, vertical spontaneous eye movements following pontine hemorrhage is not well understood. Here, we present and discuss...
