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Time-resolved Fluorescence DNA-based Sensors for Reducing Background Fluorescence of Environment
The fluorescence assay is one of the popular methods that is applied for detection of different targets. However, this method may show low...
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Magnetic Resonance Spectroscopy (MRS) in Alzheimer’s Disease
MRS is a noninvasive technique to measure different metabolites in the brain. Changes in the levels of certain metabolites can be used as surrogate... -
Magnetic Resonance Spectroscopy
Magnetic resonance spectroscopy (MRS) is a completely noninvasive technique which allows the detection of brain metabolites’ concentrations in vivo.... -
Study of Modification of Drug Binding Site I of Human Serum Albumin by Sodium Hypochlorite by Time Resolved Fluorescent Spectroscopy
Abstract —The kinetics of fluorescence decay of the K-35 probe and the tryptophan amino acid residue were measured after the addition of sodium...
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Application of NMR Spectroscopy in Viral Assembly Characterization
Nuclear Magnetic Resonance (NMR) spectroscopy is a powerful technique widely utilized for small molecule and biomolecule characterization in both... -
Investigation of Serum Albumin Conformational Changes in Melancholic Depression under Pharmacotherapy Using Subnanosecond Fluorescent Spectroscopy
AbstractThe aim of the study was to investigate the serum albumin conformation in patients with melancholic depression. There were investigated 22...
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Raman Spectroscopy for Detecting Neurological Disorders: Progress and Prospects
Raman spectroscopy (RS) is recognized as a highly sensitive and label-free technique capable of providing biochemical information about cells,... -
Profiling Complex RAS-Effector Interactions Using NMR Spectroscopy
Knowledge of how effectors interact with RAS GTPases is key to understanding how these switch-like proteins function in cells. Effectors bind... -
Assessment of Ligament Viscoelastic Properties Using Raman Spectroscopy
Injuries to the ligaments of the knee commonly impact vulnerable and physically active individuals. These injuries can lead to the development of...
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Bright New World: Principles of Fluorescence and Applications in Spectroscopy and Microscopy
The study of fluorescence has revolutionized biomedical research. Since it was first described almost two centuries ago, fluorescence has transformed... -
Total Emission Time Resolved Decay: a Method for Measurement and Resolution of Broad-Band Emission
This article reports a time-resolved fluorescence data acquisition technique termed as “Total Emission Time Resolved Decay” (TETRD). TETRD is...
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MR Spectroscopy in Health and Disease
Magnetic resonance spectroscopy (MRS) enables the noninvasive quantification of up to 20 neurochemicals in selected brain regions and has found many... -
Time-Resolved Imaging of Mitochondrial Flavin Fluorescence and Its Applications for Evaluating the Oxidative State in Living Cardiac Cells
Time-resolved fluorescence spectrometry is a highly valuable technological tool to detect and characterize mitochondrial metabolic oxidative changes... -
Classification algorithm for motor imagery fusing CNN and attentional mechanisms based on functional near-infrared spectroscopy brain image
With the continuing development of brain–computer interface technology, the analysis and interpretation of brain signals are becoming increasingly...
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Non-invasive Characterization of Glycosuria and Identification of Biomarkers in Diabetic Urine Using Fluorescence Spectroscopy and Machine Learning Algorithm
The current study presents a steadfast, simple, and efficient approach for the non-invasive determination of glycosuria of diabetes mellitus using...
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Impact of repetitive transcranial magnetic stimulation on cortical activity: a systematic review and meta-analysis utilizing functional near-infrared spectroscopy evaluation
BackgroundRepeated transcranial magnetic stimulation (rTMS) could induce alterations in cortical excitability and promote neuroplasticity. To...
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Biointerface Characterization by Nonlinear Optical Spectroscopy
Surface-specific second-order nonlinear optical spectroscopies, such as second harmonic generation (SHG) spectroscopy and sum frequency generation... -
Force Spectroscopy in Mechanical Protein Domains Unfolding
Single molecule force spectroscopy (SMFS) has emerged since the past few years as a prominent set of techniques, within the broader field of atomic... -
Structural Fingerprinting of Antisense Oligonucleotide Therapeutics by Solution NMR Spectroscopy
PurposeAntisense oligonucleotide (ASO) therapeutics are an emerging class of biopharmaceuticals to treat and prevent diseases, particularly those...