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Efficacy and Safety of Alteplase Combined with Urinarykallid for Intravenous Thrombolysis on Acute Cerebral Infarction
AbstractThis study aimed to explore the efficacy and safety of alteplase combined with urinarykallid for the intravenous thrombolysis of patients...
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Acoustic Vortex-Assisted Thrombolysis Treatment in a Pulmonary Embolism Model Using a Miniature Ultrasound Catheter
PurposePulmonary embolism (PE) occurs when a blood clot, usually from the deep veins of the legs, travels through the bloodstream and becomes lodged...
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An Explainable Machine-Learning Model to Analyze the Effects of a PCSK9 Inhibitor on Thrombolysis in STEMI Patients
PurposeThrombolysis, a timely and simple reperfusion therapy, does not have a sufficiently high success rate in patients with ST-segment elevation...
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The relationship between systemic inflammation index, systemic immune-inflammatory index, and inflammatory prognostic index and 90-day outcomes in acute ischemic stroke patients treated with intravenous thrombolysis
Background and purposeTo explore the association of systemic inflammatory index (SIRI), systemic immune-inflammatory index (SII) and inflammatory...
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Multiphysics Modelling and Simulation of Thrombolysis via Activated Platelet-Targeted Nanomedicine
PurposeThis study establishes a multiphysics simulation platform for both conventional and targeted thrombolysis using tissue plasminogen activator...
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Correlation between LOX-1 and CX3CR1 and Vascular Endothelial Function, Fibrinolytic Activity, and Recurrence after Thrombolysis in Patients with Cerebral Infarction
AbstractThis study analyzed the relationship between LOX-1 and CX3CR1 and vascular endothelial function, fibrinolytic activity, and recurrence rate...
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Synthetic role of miR-411-5p and CT perfusion information in predicting clinical outcomes after thrombolysis in acute cerebral infarction
BackgroundOur aim was to investigate the predictive value of microRNA (miR)-411-5p and computed tomography perfusion (CTP) parameters on the...
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Carboxypeptidase U (TAFIa) Is Rapidly Activated and Deactivated Following Thrombolysis and Thrombectomy in Stroke Patients
The antifibrinolytic enzyme carboxypeptidase U (CPU, TAFIa, CPB2) is an appealing target for the treatment of acute ischemic stroke (AIS). Increased...
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The association of neutrophil to lymphocyte ratio, platelet to lymphocyte ratio, and lymphocyte to monocyte ratio with post-thrombolysis early neurological outcomes in patients with acute ischemic stroke
Background and purposeTo investigate the association of neutrophil to lymphocyte ratio (NLR), platelet to lymphocyte ratio (PLR), and lymphocyte to...
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Hyper-acute EEG alterations predict functional and morphological outcomes in thrombolysis-treated ischemic stroke: a wireless EEG study
Owing to the large inter-subject variability, early post-stroke prognosis is challenging, and objective biomarkers that can provide further...
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Dynamic Neutrophil–Lymphocyte Ratios Predict Short-term Prognostic Outcome of Thrombolysis in Patients with Acute Ischemic Stroke
AimThe main purpose of this study was to investigate the dynamic changes of neutrophils-lymphocytes ratios (NLRs) in patients with acute ischemic...
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Neutrophil Counts to High-Density Lipoprotein Cholesterol Ratio: a Potential Predictor of Prognosis in Acute Ischemic Stroke Patients After Intravenous Thrombolysis
Neutrophil counts to high-density lipoprotein cholesterol ratio (NHR) is a relatively new and readily available indicator, and our study aimed to...
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Combined Therapeutics: Future Opportunities for Co-therapy with Thrombectomy
Stroke is an urgent public health issue with millions of patients worldwide living with its devastating effects. The advent of thrombolysis and...
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Dynamic Changes in Fibrinogen and Prognosis of Acute Ischemic Stroke Patients Treated with Intravenous Thrombolysis
This study aimed to investigate the association between dynamic changes in fibrinogen and the prognosis of acute ischemic stroke (AIS) patients...
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The influence of unexpected early termination of intravenous rt-PA treatment on clinical outcome in acute ischemic stroke patients
IntroductionThis study aimed to explore the impact of unexpected early termination during intravenous thrombolysis on clinical prognosis in patients...
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Multicentric validation of a reduced features case-mix set for predicting functional outcome after ischemic stroke in Belgium
IntroductionIschemic stroke is the second cause of death and leading cause of severe disability worldwide. A reduced features set of CT-DRAGON (age,...
