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Low-frequency Stimulation at the Subiculum Prevents Extensive Secondary Epileptogenesis in Temporal Lobe Epilepsy
Secondary epileptogenesis is characterized by increased epileptic susceptibility and a tendency to generate epileptiform activities outside the...
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Molecular Profiling of VGluT1 AND VGluT2 Ventral Subiculum to Nucleus Accumbens Shell Projections
The nucleus accumbens shell is a critical node in reward circuitry, encoding environments associated with reward. Long-range inputs from the ventral...
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Immunohistochemical field parcellation of the human hippocampus along its antero-posterior axis
The primate hippocampus includes the dentate gyrus, cornu ammonis (CA), and subiculum. CA is subdivided into four fields (CA1-CA3, plus CA3h/hilus of...
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Basal Forebrain Cholinergic Innervation Induces Depression-Like Behaviors Through Ventral Subiculum Hyperactivation
Malfunction of the ventral subiculum (vSub), the main subregion controlling the output connections from the hippocampus, is associated with major...
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Computational Neuroscience: Hippocampus
Extensive computational neuroscience research has addressed the functional role of the hippocampus and associated cortical structures. In this field,...
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Unlocking the Memory Vault: Dopamine, Novelty, and Memory Consolidation in the Hippocampus
Most everyday memories, including numerous episodic memories formed automatically in the hippocampus, are forgotten. However, some memories are...
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Reconstruction of the Hippocampus
The hippocampus is a widely studied brain region thought to play an important role in higher cognitive functions such as learning, memory, and...
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Atrophy patterns in hippocampus and amygdala subregions of depressed patients with Parkinson's disease
We aimed to explore the subregional atrophy patterns of the amygdala and hippocampus in Parkinson's disease (PD) with depression and their...
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Hippocampus: Molecular, Cellular, and Circuit Features in Anxiety
Anxiety disorders are currently a major psychiatric and social problem, the mechanisms of which have been only partially elucidated. The hippocampus...
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Mechanisms of Functioning of the Connectome Including the Neocortex, Hippocampus, Basal Ganglia, Cerebellum, and Thalamus
Possible mechanisms of the interactions of neuron functioning in the connectome including topographically connected areas of the neocortex,...
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Tau isoforms are differentially expressed across the hippocampus in chronic traumatic encephalopathy and Alzheimer’s disease
Chronic traumatic encephalopathy (CTE) is a progressive neurodegenerative disease, characterized by hyperphosphorylated tau, found in individuals...
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Volume changes of hippocampal and amygdala subfields in patients with mild cognitive impairment and Alzheimer’s disease
BackgroundAutomated segmentation of hippocampal and amygdala subfields could improve classification accuracy of Mild Cognitive Impairments (MCI) and...
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A novel transgenic mouse line with hippocampus-dominant and inducible expression of truncated human tau
BackgroundIntraneuronal accumulation of hyperphosphorylated tau is a defining hallmark of Alzheimer’s disease (AD). However, mouse models imitating...
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The Role of the Hippocampus in the Perception and Recall of Odors. A Hypothetical Neural Mechanism
A mechanism for the interdependent functioning of the olfactory and hippocampal neural networks is proposed. This functioning involves a significant...
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Hippocampal subfield volumes in mild cognitive impairment and alzheimer’s disease: a systematic review and meta-analysis
The hippocampus is a complex structure that consists of several subfields with distinct and specialized functions. Although numerous studies have...
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Intermittent Fasting Improves Social Interaction and Decreases Inflammatory Markers in Cortex and Hippocampus
Autism spectrum disorder (ASD) is a psychiatric condition characterized by reduced social interaction, anxiety, and stereotypic behaviors related to...
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Vector trace cells in the subiculum of the hippocampal formation
Successfully navigating in physical or semantic space requires a neural representation of allocentric (map-based) vectors to boundaries, objects and...
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Differentiated somatic gene expression is triggered in the dorsal hippocampus and the anterior retrosplenial cortex by hippocampal synaptic plasticity prompted by spatial content learning
Hippocampal afferent inputs, terminating on proximal and distal subfields of the cornus ammonis (CA), enable the functional discrimination of ‘what’...
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Predictors of hippocampal tauopathy in people with and at risk for human immunodeficiency virus infection
Combination antiretroviral therapy (cART) has extended lifespans of people living with HIV (PWH), increasing both the risk for age-related...
