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Skin Regeneration
The engineering of skin substitutes and their applications on the regeneration of damaged skin have advanced dramatically in the past decades....
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3D Bioprinting of Skin Tissue Model
The challenges and potential of using tissue engineering and regenerative medicine to create functional skin tissue constructs. While traditional...
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The Influence of Various Freezing–thawing Methods of Skin on Drug Permeation and Skin Barrier Function
The selection of skin is crucial for the in vitro permeation test (IVPT). The purpose of this study was to investigate the influence of different...
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Skin Microbiome, Metabolome and Skin Phenome, from the Perspectives of Skin as an Ecosystem
Skin is a complex ecosystem colonized by millions of microorganisms, including bacteria, fungi, and viruses. Skin microbiota is believed to exert...
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Controlling skin microbiome as a new bacteriotherapy for inflammatory skin diseases
The skin serves as the interface between the human body and the environment and interacts with the microbial community. The skin microbiota consists...
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Changes in human skin composition due to intrinsic aging: a histologic and morphometric study
Skin represents the main barrier against the external environment, but also plays a role in human relations, as one of the prime determinants of...
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Regeneration of skin appendages and nerves: current status and further challenges
Tissue-engineered skin (TES), as an analogue of native skin, is promising for wound repair and regeneration. However, a major drawback of TES...
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Revisiting the Effect of Aging on the Transport of Molecules through the Skin
Both intrinsic and extrinsic aging lead to a series of morphological changes in the skin including the flattening of the dermal–epidermal junction,...
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Immune cell trafficking: a novel perspective on the gut-skin axis
Immune cell trafficking, an essential mechanism for maintaining immunological homeostasis and mounting effective responses to infections, operates...
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Role of umbilical cord mesenchymal stromal cells in skin rejuvenation
Aging is the main cause of many degenerative diseases. The skin is the largest and the most intuitive organ that reflects the aging of the body....
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Artificial Skin Models for Animal-Free Testing: 3D Skin Reconstruct Approach, a Journey in the Past Two Decades
Growing ethical concerns regarding the use of animals in research have managed to the creation of several alternative procedures based on the...
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Basic Aspects of Skin Tissue Engineering: Cells, Biomaterials, Scaffold Fabrication Techniques, and Signaling Factors
PurposeSkin injuries are a worldwide health issue that affects millions of people each year. Tissue engineering has the potential to provide an...
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A Comprehensive Literature Review on Advancements and Challenges in 3D Bioprinting of Human Organs: Ear, Skin, and Bone
The field of 3D bioprinting is rapidly emerging within the realm of regenerative medicine, offering significant potential in dealing with the issue...
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Preparation of Conotoxin-Encapsulated Chitosan Nanoparticles and Evaluation of Their Skin Permeability
μ-Conotoxin CnIIIC (conotoxin, CTX)–loaded chitosan nanoparticles (CTX-NPs) were prepared using the ionic cross-linking method. The CTX-NPs were...
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Skin-on-Chip
In the last few decades, skin bioengineering has undergone several advancements. The need, understanding, and importance of develo** artificial...
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A Comparative Analysis of Biological and Synthetic Skin Models for Drug Transport Studies
Ethical restrictions as well as practical or economic issues related to use of animal and human skin has been the main reason the growth in the...
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Fabrication of Ready-to-Use Ex Vivo Human Skin Models for Chemical Testing: Current Status and Challenges
The skin is the largest organ of the body, composed of the epidermis, dermis, and subcutaneous tissue, each with unique functions. The development of...
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Effects of Gly-His-Lys-D-Ala Peptide on Skin Wound Regeneration Processes
We evaluated the effects of the Gly-His-Lys-D-Ala peptide in a dose 0.5 μg/kg on skin wound regeneration in male Wistar rats ( n =80) after initial...
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Senescent fibroblast facilitates re-epithelization and collagen deposition in radiation-induced skin injury through IL-33-mediated macrophage polarization
BackgroundThe need for radiotherapy among the elderly rises with increasing life expectancy and a corresponding increase of elderly cancer patients....
