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Smartphone-based thermography to determine shunt patency in patients with hydrocephalus
BackgroundWhen shunt dysfunction is suspected, radiation exposure due to X-rays or a CT-scan is inevitable. Less-invasive and more reliable methods...
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Bacterial ventriculoperitoneal shunt infections: changing trends in antimicrobial susceptibility, a 7-year retrospective study from Pakistan
BackgroundVentriculoperitoneal (VP) shunt infections in adults represent a severe complication and make treatment more challenging. Therefore, drug...
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An unusual case of endotipsitis: persistent infection and migration to the right atrium of a transjugular intrahepatic portosystemic shunt (TIPS)
Endotipsitis is an underdiagnosed entity mainly because it requires a high initial level of suspicion. It should be considered in the differential...
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Cerebrospinal fluid shunt surgery reduces the risk of develo** dementia and Alzheimer’s disease in patients with idiopathic normal pressure hydrocephalus: a nationwide population-based propensity-weighted cohort study
BackgroundPatients with idiopathic normal-pressure hydrocephalus (iNPH) are predisposed to develo** dementing disorders. Cerebrospinal fluid (CSF)...
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True infection or contamination in patients with positive Cutibacterium blood cultures—a retrospective cohort study
Cutibacterium is a genus often considered a contaminant when present in blood cultures, but it can also cause severe infections, especially related...
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Physical exercise and goal attainment after shunt surgery in idiopathic normal pressure hydrocephalus: a randomised clinical trial
BackgroundRehabilitation in iNPH is suggested to be an important factor to improve patients’ functions but there are lack of clinical trials...
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External ventriculostomy-associated infection reduction after updating a care bundle
BackgroundDespite the clinical benefits of external ventricular drains (EVD), these devices can lead to EVD-related infections (EVDRI). The drainage...
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Cerebrospinal fluid biomarkers of neuroinflammation in children with hydrocephalus and shunt malfunction
BackgroundApproximately 30% of cerebrospinal fluid (CSF) shunt systems for hydrocephalus fail within the first year and 98% of all patients will have...
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Lumbar and ventricular CSF concentrations of extracellular matrix proteins before and after shunt surgery in idiopathic normal pressure hydrocephalus
BackgroundIdiopathic normal pressure hydrocephalus (iNPH) is a reversible CNS disease characterized by disturbed cerebrospinal fluid (CSF) dynamics....
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Intraventricular or intrathecal polymyxin B for treatment of post-neurosurgical intracranial infection caused by carbapenem-resistant gram-negative bacteria: a 8-year retrospective study
PurposePost-neurosurgical intracranial infection caused by carbapenem-resistant gram-negative bacteria (CRGNB) is a life-threatening complication....
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Characterization of a multicenter pediatric-hydrocephalus shunt biobank
BackgroundPediatric hydrocephalus is a devastating and costly disease. The mainstay of treatment is still surgical shunting of cerebrospinal fluid...
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Microbiological profile and infection potential of different cryopreserved skull flaps after decompressive hemicraniectomy. Is cryopreservation at − 80 ℃ better?
ObjectivePatterns of cryopreservation of explanted skull bone flaps have long been a matter of debate, in particular the appropriate temperature of...
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Flow Monitoring of ECMO Circuit for Detecting Oxygenator Obstructions
Oxygenator thrombosis during extracorporeal membrane oxygenation (ECMO), is a complication that necessitates component replacement. ECMO centers...
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Central Nervous System Tuberculosis: Pathogenesis, Diagnosis, and Management
Tuberculosis (TB) affects theSystemcentral nervous central nervous systemCNSCentral nervous system (CNS) in several distinct but interrelated ways....
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Ventriculoatrial shunt as a feasible regimen for certain patients of hydrocephalus: clinical features and surgical management
Ventriculoatrial (VA) shunt is one of the most commonly used solutions for hydrocephalus. In recent years, the number of VA shunt has decreased...
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Racemose neurocysticercosis simulating tuberculous meningitis
We report a patient with racemose neurocysticercosis, highlighting the diagnostic and management issues. A 37-year-old male had headaches, fever, and...
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Energy Balance and Neuroendocrine-Immune Regulation in Chronic Inflammatory and Neoplastic Diseases: An Evolutionary Perspective
The central nervous and immune systems are often in competition for energy substrates. After infection or injury, energy expenditure typically...
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CSF inflammatory markers differ in gram-positive versus gram-negative shunt infections
BackgroundCerebrospinal fluid (CSF) shunt placement is frequently complicated by bacterial infection. Shunt infection diagnosis relies on bacterial...
