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Racial disparity in prostate cancer: an outlook in genetic and molecular landscape
Prostate cancer (PCa) incidence, morbidity, and mortality rates are significantly impacted by racial disparities. Despite innovative therapeutic...
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Cancer Statistics: Geographical and Racial Disparities
Cancer leads to millions of morbidities and mortalities throughout the world, annually. There are well-established discrepancies in cancer incidence... -
Racial disparities in breast cancer preclinical and clinical models
Breast cancer (BCa) has long been a health burden to women across the globe. However, the burden is not equally carried across races. Though the...
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Cancer Statistics: Geographical and Racial Disparities
Cancer leads to millions of morbidities and mortalities throughout the world, annually. There are well-established discrepancies in cancer incidence... -
Cancer: Epidemiology, Racial, and Geographical Disparities
Cancer is a complex and multifaceted disease that affects millions of people worldwide. The epidemiology of cancer is a critical area of research... -
Racial and ethnic variation in BRCA1 and BRCA2 genetic test results among individuals referred for genetic counseling at a large urban comprehensive cancer center
PurposeThe prevalence of pathogenic variants in BRCA1 and BRCA2 in populations other than Ashkenazi Jewish (AJ) is not well defined. We describe the...
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Structural Inequity and Racial/Ethnic Disparities in Sleep Health During the COVID-19 Pandemic
The onset of the coronavirus disease of 2019 (COVID-19) pandemic and resulting global lockdowns, hospitalizations, and increased unemployment rates... -
Racial and ethnic disparities in genetic testing for hearing loss: a systematic review and synthesis
Racial/ethnic disparities in the diagnostic efficacy of genetic testing for hearing loss have been described. These disparities may relate to...
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Racial and ethnic disparities in diagnostic efficacy of comprehensive genetic testing for sensorineural hearing loss
Understanding racial and ethnic disparities in diagnostic rates of genetic testing is critical for health equity. We sought to understand the extent...
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Racial differences in RAD51 expression are regulated by miRNA-214-5P and its inhibition synergizes with olaparib in triple-negative breast cancer
BackgroundTriple-negative breast cancer (TNBC) affects young women and is the most aggressive subtype of breast cancer (BC). TNBCs disproportionally...
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Breast cancer disparities in outcomes; unmasking biological determinants associated with racial and genetic diversity
Breast cancer (BC) remains a leading cause of death among women today, and mortality among African American women in the US remains 40% higher than...
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Prostate cancer metastasis and health disparities: a systematic review
BackgroundProstate cancer (PCa), one of the most prevalent malignancies affecting men, significantly contributes to increased mortality rates...
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Ethnic-specific genetic susceptibility loci for endometriosis in Taiwanese-Han population: a genome-wide association study
Endometriosis is a common gynecological disorder affecting around 10% of reproductive-age women. Although many hypotheses were proposed, genetic...
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Exploring Racial Differences in Treatment Decision-making in Chinese Immigrant and White American Breast Cancer Patients: the Role of Patient-Provider Communication
Chinese immigrant cancer patients report suboptimal patient-provider communication, which increases the likelihood of decisional conflict and...
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Cancer health disparities in racial/ethnic minorities in the United States
There are well-established disparities in cancer incidence and outcomes by race/ethnicity that result from the interplay between structural,...
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Racial differences in prostate cancer: does timing of puberty play a role?
The burden of prostate cancer has a remarkably disproportionate distribution across racial groups. For example, in the USA, African Americans are...
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Racial differences in CD8+ T cell infiltration in breast tumors from Black and White women
BackgroundAfrican American/Black women with breast cancer have poorer survival than White women, and this disparity persists even after adjusting for...
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Healthcare disparities, screening, and molecular testing in the changing landscape of non–small cell lung cancer in the United States: a review
Inequitable access to care continues to hinder improvements in diagnosis and treatment of lung cancer. This review describes healthcare disparities...
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Genomic supremacy: the harm of conflating genetic ancestry and race
BackgroundRecent studies have reignited the tinderbox of debate surrounding the use of race and ancestry in medicine. These controversial studies...