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  1. Brain fiber structure estimation based on principal component analysis and RINLM filter

    Diffusion magnetic resonance imaging is a technique for non-invasive detection of microstructure in the white matter of the human brain, which is...

    Yuemin Zhu, Yuanjun Wang in Medical & Biological Engineering & Computing
    Article 23 November 2023
  2. Principal Component Analysis of Grasp Force and Pose During In-Hand Manipulation

    Purpose

    The manner in which healthy humans interact with objects as they move them within the hand is essential for activities of everyday life. The...

    Dipayan Das, Joshua Schultz in Journal of Medical and Biological Engineering
    Article 07 September 2022
  3. Using principal component analysis to determine which vestibular stimuli provide best biomarkers for separating Alzheimer’s from mixed Alzheimer’s disease

    Alzheimer’s disease (AD) is often mixed with cerebrovascular disease (AD-CVD). Heterogeneity of dementia etiology and the overlap** of...

    S. Marzban, Z. Dastgheib, ... Z. Moussavi in Medical & Biological Engineering & Computing
    Article 13 May 2024
  4. Extraction and Digitization of ECG Signals from Standard Clinical Portable Document Format Files for the Principal Component Analysis of T-wave Morphology

    Introduction

    : T-wave analysis from standard electrocardiogram (ECG) remains one of the most available clinical and research methods for evaluating...

    Michal Schäfer, Max B. Mitchell, ... Johannes C. von Alvensleben in Cardiovascular Engineering and Technology
    Article 25 July 2023
  5. Tracking the Reliability of Force Plate-Derived Countermovement Jump Metrics Over Time in Female Basketball Athletes: A Comparison of Principal Component Analysis vs. Conventional Methods

    Background

    Establishing the reliability of countermovement jump (CMJ) metrics over multiple weeks can be important in understanding and tracking...

    Joshua A. J. Keogh, Chris Bishop, ... Dylan Kobsar in Journal of Science in Sport and Exercise
    Article 15 August 2023
  6. Sparse principal component analysis based on genome network for correcting cell type heterogeneity in epigenome-wide association studies

    In epigenome-wide association studies (EWAS), the mixed methylation expression caused by the combination of different cell types may lead the...

    Rui Miao, Qi Dang, ... Yong Liang in Medical & Biological Engineering & Computing
    Article 04 July 2022
  7. Iterative principal component analysis method for improvised classification of breast cancer disease using blood sample analysis

    Breast cancer is the most common cancer in women occurring worldwide. Some of the procedures used to diagnose breast cancer are mammogram, breast...

    Geetharamani R, Sivagami G in Medical & Biological Engineering & Computing
    Article 31 July 2021
  8. Quantification of Compatibility Between Polymeric Excipients and Atenolol Using Principal Component Analysis and Hierarchical Cluster Analysis

    An important challenge to overcome in the solid dosage forms technology is the selection of the most biopharmaceutically efficient polymeric...

    Barbara Rojek, Maria Gazda, Marek Wesolowski in AAPS PharmSciTech
    Article Open access 19 November 2021
  9. Image-based cell subpopulation identification through automated cell tracking, principal component analysis, and partitioning around medoids clustering

    In vitro cell culture model systems often employ monocultures, despite the fact that cells generally exist in a diverse, heterogeneous...

    Megan E. Brasch, Alexis N. Peña, James H. Henderson in Medical & Biological Engineering & Computing
    Article 31 July 2021
  10. Investigating the Impact of Gastric Emptying on Pharmacokinetic Parameters Using Delay Differential Equations and Principal Component Analysis

    Background and Objectives

    Losartan presents multiple peaks after single oral administration, which can be attributed to gastric emptying. The aim of...

    Article 25 March 2021
  11. Lymphocyte–monocyte–neutrophil index: a predictor of severity of coronavirus disease 2019 patients produced by sparse principal component analysis

    Background

    It is important to recognize the coronavirus disease 2019 (COVID-19) patients in severe conditions from moderate ones, thus more effective...

    Yingjie Qi, Jian-an Jia, ... **aoling Ma in Virology Journal
    Article Open access 04 June 2021
  12. Altered functional brain networks in coronary heart disease: independent component analysis and graph theoretical analysis

    Coronary heart disease (CHD) confers a high risk of cognitive and mental impairments in patients. This study aimed to explore the association of CHD...

    Simin Lin, Puyeh Wu, ... Hengyu Zhao in Brain Structure and Function
    Article 09 November 2023
  13. Dimensionality reduction beyond neural subspaces with slice tensor component analysis

    Recent work has argued that large-scale neural recordings are often well described by patterns of coactivation across neurons. Yet the view that...

    Arthur Pellegrino, Heike Stein, N. Alex Cayco-Gajic in Nature Neuroscience
    Article Open access 06 May 2024
  14. The metabolic spatial covariance pattern of definite idiopathic normal pressure hydrocephalus: an FDG PET study with principal components analysis

    Identification of patients with idiopathic normal pressure hydrocephalus (iNPH) in a collective with suspected neurodegenerative disease is...

    Alexander Rau, Nils Schröter, ... Lars Frings in Alzheimer's Research & Therapy
    Article Open access 18 November 2023
  15. Screening of Bioequivalent Extended-Release Formulations for Metformin by Principal Component Analysis and Convolution-Based IVIVC Approach

    Bioequivalence (BE) is usually hard to achieve for extended-release (ER) dosage form products due to not only its complicated formulation but also to...

    Yufeng Zhang, Hua Liu, ... Zhong Zuo in The AAPS Journal
    Article 04 March 2021
  16. A mediation analysis framework based on variance component to remove genetic confounding effect

    Identification of pleiotropy at the single nucleotide polymorphism (SNP) level provides valuable insights into shared genetic signals among...

    Zihan Dong, Hongyu Zhao, Andrew T. DeWan in Journal of Human Genetics
    Article 25 March 2024
  17. SMART (Splitting-Merging Assisted Reliable) Independent Component Analysis for Extracting Accurate Brain Functional Networks

    Functional networks (FNs) hold significant promise in understanding brain function. Independent component analysis (ICA) has been applied in...

    **ngyu He, Vince D. Calhoun, Yuhui Du in Neuroscience Bulletin
    Article 15 March 2024
  18. Improved robust tensor principal component analysis for accelerating dynamic MR imaging reconstruction

    Dynamic magnetic resonance imaging (dMRI) strikes a balance between reconstruction speed and image accuracy in medical imaging field. In this paper,...

    Mingfeng Jiang, Qiannan Shen, ... Ling **a in Medical & Biological Engineering & Computing
    Article 05 May 2020
  19. Biologically plausible single-layer networks for nonnegative independent component analysis

    An important problem in neuroscience is to understand how brains extract relevant signals from mixtures of unknown sources, i.e., perform blind...

    David Lipshutz, Cengiz Pehlevan, Dmitri B. Chklovskii in Biological Cybernetics
    Article 07 September 2022
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