Search
Search Results
-
Primary tumor surgery improves survival in non-metastatic primary urethral carcinoma patients: a large population-based investigation
BackgroundPrimary urethral carcinoma (PUC) is a rare genitourinary malignancy with a relatively poor prognosis. The aim of this study was to examine...
-
Incidence rates and contemporary trends in primary urethral cancer
PurposeWe assessed contemporary incidence rates and trends of primary urethral cancer.
MethodsWe identified urethral cancer patients within...
-
PD-L1 protein expression by Combined Positive Score (CPS) in patients with muscle invasive or advanced urothelial carcinoma: a single institution experience
IntroductionImmune checkpoint inhibitors have revolutionized the treatment of patients with advanced urothelial carcinoma (UC) in the frontline and...
-
Physalin A Induces Apoptosis and Autophagy in Hepatocellular Carcinoma via Inhibition of PI3K/Akt Signaling Pathway
Physalin A (PA) is a bioactive withanolide with multiple pharmacological properties and has been indicated to be cytotoxic to hepatocellular...
-
HPV infection and 5mC/5hmC epigenetic markers in penile squamous cell carcinoma: new insights into prognostics
BackgroundPenile cancer is one of the most aggressive male tumors. Although it is preventable, the main etiologic causes are lifestyle behaviors and...
-
Retrospective studies and quantitative proteomics reveal that abnormal expression of blood pressure, blood lipids, and coagulation related proteins is associated with hypospadias
Hypospadias refers to the abnormal position of the male urethral orifice, which not only leads to urination disorder but also causes sexual...
-
Intravesical Infusion of Oncolytic Virus CG0070 in the Treatment of Bladder Cancer
CG0070 is a conditionally replicating oncolytic adenovirus that preferentially replicates within and kills Rb-defective cancer cells. It has been...
-
Oncolytic adenoviral therapy plus pembrolizumab in BCG-unresponsive non-muscle-invasive bladder cancer: the phase 2 CORE-001 trial
Cretostimogene grenadenorepvec is a serotype-5 oncolytic adenovirus designed to selectively replicate in cancer cells with retinoblastoma pathway...
-
Multiple metastases of androgen indifferent prostate cancer in the urinary tract: two case reports and a literature review
BackgroundProstate cancer (PC) is mainly known to metastasize to bone, lung and liver, but isolated metastases of prostate cancer, including ductal...
-
Feasibility and safety of laparoscopic radical cystectomy for male octogenarians with muscle-invasive bladder cancer
This study was designed to evaluate the safety and feasibility of laparoscopic radical cystectomy (LRC) for male octogenarian patients with...
-
Repurposing metformin as a potential anticancer agent using in silico technique
BackgroundThe focus on repurposing readily available, well-known drugs for new, creative uses has grown recently. One such medication is metformin, a...
-
Regeneration of Urologic Tissues and Organs
Patients suffering from a variety of urologic diseases may be treated with transplanted tissues and organs. However, there is a shortage of donor...
-
Skin Cancer: Prevention and Early Detection
Melanoma and non-melanoma skin cancers are one of the most common cancers prevalent in white-skinned populations, and its rising incidence and...
-
Sexually Transmitted Diseases and COVID-19
Sexually transmitted disease (STD) refers to a disease that has developed after an infection acquired by sexual contact. Human immunodeficiency virus...
-
A randomized phase II trial of MR-guided prostate stereotactic body radiotherapy administered in 5 or 2 fractions for localized prostate cancer (FORT)
BackgroundUltra-hypofractionated regimens for definitive prostate cancer (PCa) radiotherapy are increasingly utilized due in part to promising safety...
-
Infective Syndromes: A System and Organ-Based Approach
‘Infective syndrome’ is synonymous with the term ‘Syndromic infection’. An infection manifesting as a single syndrome could be caused by a single...
-
Cytokines and Chemokines in Tumor Growth and Progression
The significance of cytokines as signaling molecules, which has long been acknowledged, is expanding as a result of their connection to malignancies...
-
Adeno-associated virus infection and its impact in human health: an overview
Discovered as a contaminant of adenovirus stocks in the 1960s, adeno-associated virus (AAV) is a mono-stranded DNA virus that depends on helper...
-
Perioperative outcomes and continence following robotic-assisted radical cystectomy with mainz pouch II urinary diversion in patients with bladder cancer
PurposeTo present the widely unknown perioperative outcomes and continence status of bladder cancer patients following robotic-assisted radical...
-
Risk factors of early bacterial infection and analysis of bacterial composition, distribution and drug susceptibility after cadaveric liver transplantation
BackgroundThis study provided a theoretical basis for the clinical diagnosis and treatment of bacterial infection after liver transplantation through...