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Morphological Changes in GABAergic Structures of the Rat Brain during Postnatal Development
Abstract —The aim of the study was to investigate brain GABAergic neurons and synaptic terminals in early postnatal development and aging. Wistar rat...
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Postnatal Development of Neuroimmune Responses
The early-life period represents a time of particular vulnerability to environmental and lifestyle stimuli that can shape our physiology long-term....
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Early postnatal microglial ablation in the Ccdc39 mouse model reveals adverse effects on brain development and in neonatal hydrocephalus
BackgroundNeonatal hydrocephalus is a congenital abnormality resulting in an inflammatory response and microglial cell activation both clinically and...
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Entry of cannabidiol into the fetal, postnatal and adult rat brain
Cannabidiol is a major component of cannabis but without known psychoactive properties. A wide range of properties have been attributed to it, such...
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Reference Gene Validation in the Embryonic and Postnatal Brain in the Rat Hyperhomocysteinemia Model
Maternal hyperhomocysteinemia (HCY) induced by genetic defects in methionine cycle enzymes or vitamin imbalance is known to be a pathologic factor...
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ARG1-expressing microglia show a distinct molecular signature and modulate postnatal development and function of the mouse brain
Molecular diversity of microglia, the resident immune cells in the CNS, is reported. Whether microglial subsets characterized by the expression of...
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Expression of Dystrophin Dp71 Splice Variants Is Temporally Regulated During Rodent Brain Development
Dystrophin Dp71 is the major product of the Duchenne muscular dystrophy ( DMD ) gene in the brain, and its loss in DMD patients and mouse models leads...
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Epigenetic Influences and Brain Development
Recent years have seen raid growth in the quantity of scientific data on the involvement of epigenetic processes in regulating brain development...
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Developmental brain lipidomics is influenced by postnatal chlorpyrifos exposure and APOE genetic background in mice
Lipids are a major component of the brain, and are involved in structural and neurodevelopmental processes such as neurogenesis, synaptogenesis and...
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Maternal immunoglobulins are distributed in the offspring’s brain to support the maintenance of cortical interneurons in the postnatal period
It is known that maternal immunoglobulins (Igs) are transferred to the offspring across the placenta. However, receiving maternal Igs, especially...
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Hemodynamics During Development and Postnatal Life
A well-developed heart is essential for embryonic survival. There are constant interactions between cardiac tissue motion and blood flow, which...
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Maternal immunoglobulin G affects brain development of mouse offspring
Maternal immunoglobulin (Ig)G is present in breast milk and has been shown to contribute to the development of the immune system in infants. In...
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Vascular network expansion, integrity of blood–brain interfaces, and cerebrospinal fluid cytokine concentration during postnatal development in the normal and jaundiced rat
BackgroundSevere neonatal jaundice resulting from elevated levels of unconjugated bilirubin in the blood induces dramatic neurological impairment....
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Development of a method for isolating brain capillaries from a single neonatal mouse brain and comparison of proteomic profiles between neonatal and adult brain capillaries
BackgroundThe functions and protein expressions of the blood–brain barrier are changed throughout brain development following birth. This study aimed...
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Early development of the functional brain network in newborns
During the prenatal period and the first postnatal years, the human brain undergoes rapid growth, which establishes a preliminary infrastructure for...
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Endothelial Rbpj Is Required for Cerebellar Morphogenesis and Motor Control in the Early Postnatal Mouse Brain
Intercellular influences are necessary for coordinated development and function of vascular and neural components in the brain. In the early...
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Brain is modulated by neuronal plasticity during postnatal development
Neuroplasticity is referred to the ability of the nervous system to change its structure or functions as a result of former stimuli. It is a...
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Regulation of Morphogenetic Processes during Postnatal Development and Physiological Regeneration of the Adrenal Medulla
Regulation of morphogenetic processes during postnatal development of the rat adrenal medulla was studied. Termination of the adrenal medulla growth...
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The subcommissural organ regulates brain development via secreted peptides
The subcommissural organ (SCO) is a gland located at the entrance of the aqueduct of Sylvius in the brain. It exists in species as distantly related...
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The ventricular-subventricular, subgranular and subcallosal zones: three niches of neural stem cells in the postnatal brain
In the postnatal brain, three regions show high mitotic activity. These brain areas are neurogenic niches, and each niche harbors a microenvironment...
