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Magnetic Resonance Spectroscopy
Magnetic resonance spectroscopy (MRS) is a completely noninvasive technique which allows the detection of brain metabolites’ concentrations in vivo.... -
Functional Imaging: Magnetic Resonance Imaging
Magnetic resonance imaging (MRI) has had a substantial clinical impact since the first commercial scanners were introduced in the early 1980s. The... -
In Vivo 13C Magnetic Resonance Spectroscopy for Assessing Brain Biochemistry in Health and Disease
Magnetic resonance spectroscopy (MRS) is a non-invasive technique that contributes to the elucidation of brain biochemistry. 13 C MRS enables the...
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Neurochemical abnormalities in chronic fatigue syndrome: a pilot magnetic resonance spectroscopy study at 7 Tesla
RationaleChronic fatigue syndrome (CFS) is a common and burdensome illness with a poorly understood pathophysiology, though many of the...
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Potential of Magnetic Resonance (MR) Methods in Clinical Cancer Research
Magnetic resonance imaging (MRI) is often used as a versatile imaging modality for diagnosis of various diseases in clinical medicine. The technique... -
Nuclear Magnetic Resonance Spectroscopy
Nuclear magnetic resonance (NMR) spectroscopy is usually combined with infrared (IR) spectroscopy for the complete analysis of the structure of an... -
MR Spectroscopy in Health and Disease
Magnetic resonance spectroscopy (MRS) enables the noninvasive quantification of up to 20 neurochemicals in selected brain regions and has found many... -
Magnetic Resonance Imaging for Drug Development
Given the merit of high-resolution cross-sectional imaging, magnetic resonance imaging (MRI) has been utilized in many preclinical and clinical... -
A proton birdcage coil integrated with interchangeable single loops for multi-nuclear MRI/MRS
Energy metabolism is fundamental for life. It encompasses the utilization of carbohydrates, lipids, and proteins for internal processes, while...
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MR Spectroscopy in Health and Disease
Magnetic resonance spectroscopy (MRS) enables the noninvasive quantification of up to 20 neurochemicals in selected brain regions and has found many... -
Structural Fingerprinting of Antisense Oligonucleotide Therapeutics by Solution NMR Spectroscopy
PurposeAntisense oligonucleotide (ASO) therapeutics are an emerging class of biopharmaceuticals to treat and prevent diseases, particularly those...
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Biosensing Technologies for Detection of Extracellular Vesicles
Extracellular vesicles (EVs) are novel biomarkers evaluated during liquid biopsy and are involved in many physiological functions in cells as well as... -
Relationship between brain iron deposition and mitochondrial dysfunction in idiopathic Parkinson’s disease
BackgroundThe underlying pathophysiology of Parkinson's disease is complex, involving different molecular pathways, including brain iron deposition...
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A Review of Translational Magnetic Resonance Imaging in Human and Rodent Experimental Models of Small Vessel Disease
Cerebral small vessel disease (SVD) is a major health burden, yet the pathophysiology remains poorly understood with no effective treatment. Since...
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Nerve Injury and Biomarkers
The nervous system has enormous scale to its production. From the large-scale ganglia to the microscopic neuron, there is tremendous communication... -
Degradants of Tenofovir Disoproxil Fumarate Under Forced Yet Mild Thermal Stress: Isolation, Comprehensive Structural Elucidation, and Mechanism
In addition to understanding the mechanism of action for a specific drug candidate, information regarding degradation pathways/products under various...
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Analytical Techniques in Medical Biotechnology
Biomedical research, diagnosis, and treatment thrive on the use of various analytical biotechniques. These analytical biotechniques include a vast... -
A Diagnostic Perspective of Schizophrenia: From Past to Present
Schizophrenia is a chronic manic-depressive illness. It is a mental illness characterized by a combination of symptoms such as perceptual... -
Design and synthesis of multi-targeted nanoparticles for gene delivery to breast cancer tissues
Biocompatibility of nanoparticles is the most essential factor in their use in clinical applications. In this study, hyperbranched spermine (HS),...