Abstract
Nuclear magnetic resonance (NMR) spectroscopy is usually combined with infrared (IR) spectroscopy for the complete analysis of the structure of an unknown molecule. IR spectroscopy is used to detect a functional group in the sample, whereas NMR spectroscopy detects number of atoms and their type in sample. NMR technique can detect many nuclei but mostly identifies carbon-hydrogen frameworks. In this chapter, we have comprehensively discussed the NMR spectroscopy, its types, basic mechanism along with its instrumentation, applications, advantages, and disadvantages.
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19 July 2022
The original version of the book has been updated after publication.
Further Reading
Beckett A, Stenlake J (1997) Practical pharmaceutical chemistry, part II, vol 1. CBS Publications and Distributors, New Delhi, pp 275–300
Bovey FA, Mirau PA, Gutowsky H (1988) Nuclear magnetic resonance spectroscopy. Elsevier, Amsterdam
Bruch M (1996) NMR spectroscopy techniques. CRC Press, Boca Raton
Creaser CS, Davies AMC (1988) Analytical applications of Spectroscopy. Blackwell Science, Oxford
Ernst RR, Bodenhausen G, Wokaun A (1987) Principles of nuclear magnetic resonance in one and two dimensions. Clarendon Press, Oxford
Gauglitz G, Dakin JP (2017) Spectroscopic analysis. In: John PD, Robert GWB (eds) Handbook of optoelectronics, vol 2. CRC Press, Boca Raton, pp 569–600
Gauglitz G, Moore DS, Vo-Dinh T (2014) Handbook of spectroscopy. Wiley, Hoboken
Holzgrabe U (2017) NMR spectroscopy in pharmaceutical analysis. Elsevier, Amsterdam
Ionin B, Ershov BA, Kol’tsov A (1983) NMR spectroscopy in organic chemistry, vol 167. Khimiya, Leningrad
Jackman L (2012) Dynamic nuclear magnetic resonance spectroscopy. Elsevier, Amsterdam
Lambert JB, Mazzola EP, Ridge CD (2019a) Nuclear magnetic resonance spectroscopy: an introduction to principles, applications, and experimental methods. Wiley, Hoboken
Lambert JB, Mazzola EP, Ridge CD (2019b) Nuclear magnetic resonance spectroscopy: an introduction to principles, applications, and experimental methods. Wiley, Hoboken
Lehmann T (2018) Nuclear magnetic resonance spectroscopy. Multidisciplinary Digital Publishing Institute, Basel
LibreTexts™. Analytical methods in spectroscopy. Accessed 2 Oct 2019
LibreTexts™. Nuclear magnetic resonance spectroscopy. Accessed 22 Aug 2019
Mooney EF (1970) Annual reports on NMR spectroscopy. Academic Press, Cambridge
Myers RJ (1973) Molecular magnetism and magnetic resonance spectroscopy. Prentice-Hall, New York
Nöth H, Wrackmeyer B (2012) Nuclear magnetic resonance spectroscopy of boron compounds. Springer, Berlin
Reichenbächer M, Popp J (2012) Challenges in molecular structure determination. Springer, Berlin
Waters Corporation. Nuclear magnetic resonance spectroscopy. Accessed 21 Aug 2019
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Akash, M.S.H., Rehman, K. (2020). Nuclear Magnetic Resonance Spectroscopy. In: Essentials of Pharmaceutical Analysis. Springer, Singapore. https://doi.org/10.1007/978-981-15-1547-7_10
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DOI: https://doi.org/10.1007/978-981-15-1547-7_10
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