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Methods to Measure Water Permeability
Water permeability is a key feature of the cell plasma membranes, and it has seminal importance for several cell functions such as cell volume...
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Lymphatic Vascular Permeability Determined from Direct Measurements of Solute Flux
The permeability of the lymphatic vasculature is tightly regulated to prevent the excessive leakage of lymph into the tissues, which has profound...
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Determination of Solute Permeability of Microvascular Endothelial Cell Monolayers In Vitro
The microvascular endothelium has a critical role in regulating the delivery of oxygen, nutrients, and water to the surrounding tissues. Under...
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A pilot study to assess blood-brain barrier permeability in long COVID
The etiology of brain fog associated with long COVID is not clear. Based on some preliminary work, disruption of the blood-brain barrier has been...
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Erk5 functions in modulation of zebrafish intestinal permeability
The intestine of zebrafish consists of mucosa, muscularis and serosa. Intestinal epithelial cells (IECs) act as a physical and biochemical barrier to...
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Estimating the Ca2+ Permeability of NMDA Receptors with Whole-Cell Patch-Clamp Electrophysiology
In the mammalian central nervous system (CNS), fast excitatory transmission relies primarily on the ionic fluxes generated by ionotropic glutamate...
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Computational Analysis of the Effects of Fiber Deformation on the Microstructure and Permeability of Blood Oxygenator Bundles
Mechanical loads on the polymeric fibers of oxygenating bundles are commonly present due to bundle press-fitting during device assembly and blood...
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ZNF787 and HDAC1 Mediate Blood–Brain Barrier Permeability in an In Vitro Model of Alzheimer’s Disease Microenvironment
The permeability of the blood–brain barrier (BBB) is increased in Alzheimer’s disease (AD). This plays a key role in the instigation and maintenance...
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Establishment of the deuterium oxide dilution method as a new possibility for determining the transendothelial water permeability
Increase in transendothelial water permeability is an essential etiological factor in a variety of diseases like edema and shock. Despite the high...
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Effects of bovine whey protein on exercise-induced gut permeability in healthy adults: a randomised controlled trial
PurposeIntestinal permeability is a critical component of gut barrier function. Barrier dysfunction can be triggered by certain stressors such as...
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Influence of Bile Acids on Clindamycin Hydrochloride Skin Permeability: In Vitro and In Silico Preliminary Study
Background and ObjectiveTopical clindamycin formulations are widely used in clinical practice, but poor bioavailability and restricted skin...
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Tumor-derived exosomal ADAM17 promotes pre-metastatic niche formation by enhancing vascular permeability in colorectal cancer
BackgroundHematological metastasis has been recognized as a crucial factor contributing to the high rates of metastasis and mortality observed in...
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Intestinal epithelial Krüppel-like factor 4 alleviates endotoxemia and atherosclerosis through improving NF-κB/miR-34a-mediated intestinal permeability
Maintenance of intestinal barrier function contributes to gastrointestinal homeostasis and therefore cardiovascular diseases. A number of studies...
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Tricaprin as a membrane permeability regulator: sustained small hydrophilic substance release from liposomes
PurposeIncorporating fatty acids into the phospholipid bilayer affects membrane packing order and permeability. We recently demonstrated that...
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Effects of sevoflurane on lung epithelial permeability in experimental models of acute respiratory distress syndrome
BackgroundPreclinical studies in acute respiratory distress syndrome (ARDS) have suggested that inhaled sevoflurane may have lung-protective effects...
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Monte Carlo Optimization Method Based QSAR Modeling of Placental Barrier Permeability
PurposeIn order to ensure that drug administration is safe during pregnancy, it is crucial to have the possibility to predict the placental...
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Evaluation of Vascular Permeability in Inflamed Vessels of the Cremaster Muscle in Live Mice
Inflammation in vascular structures due to external factors such as injury or infection inevitably leads to blood leakage. Therefore, measuring blood...
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Mertk Reduces Blood-Spinal Cord Barrier Permeability Through the Rhoa/Rock1/P-MLC Pathway After Spinal Cord Injury
Disruption of the blood-spinal cord barrier (BSCB) is a critical event in the secondary injury following spinal cord injury (SCI). Mertk has been...
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TFAM-Mediated mitochondrial transfer of MSCs improved the permeability barrier in sepsis-associated acute lung injury
Vascular endothelial cell barrier disruption is a hallmark of sepsis-induced acute lung injury (ALI). Mesenchymal stem cells (MSCs)-based therapy has...
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Characterization of critical parameters using an air–liquid interface model with RPMI 2650 cells for permeability studies of small molecules
The field of nasal drug delivery gained enormously on interest over the past decade. Performing nasal in vivo studies is expensive and...
