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Long-Term Depression at Parallel Fiber–Purkinje Cell Synapses
Long-term depression (LTD) at parallel fiber (PF)–Purkinje cell (PC) synapses plays an important role in cerebellar oculomotor control and classical... -
Neuronal Nitric Oxide Synthase Regulates Cerebellar Parallel Fiber Slow EPSC in Purkinje Neurons by Modulating STIM1-Gated TRPC3-Containing Channels
Responding to burst stimulation of parallel fibers (PFs), cerebellar Purkinje neurons (PNs) generate a convolved synaptic response displaying a fast...
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Individualized microbiotas dictate the impact of dietary fiber on colitis sensitivity
BackgroundThe observation that the intestinal microbiota is central in the development of IBD suggests that dietary fiber, the microbiota’s primary...
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Signal transformation in refractometric fiber-optic microsensors in life support systems
The physical, technical, and functional properties of signal conversion in the optical system of high-precision fiber-optic microsensors implementing...
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State and rate-of-change encoding in parallel mesoaccumbal dopamine pathways
The nervous system uses fast- and slow-adapting sensory detectors in parallel to enable neuronal representations of external states and their...
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Brain fiber structure estimation based on principal component analysis and RINLM filter
Diffusion magnetic resonance imaging is a technique for non-invasive detection of microstructure in the white matter of the human brain, which is...
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MaPPeRTrac: A Massively Parallel, Portable, and Reproducible Tractography Pipeline
Large-scale diffusion MRI tractography remains a significant challenge. Users must orchestrate a complex sequence of instructions that requires many...
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Assessment of Mechanically Induced Changes in Helical Fiber Microstructure Using Diffusion Tensor Imaging
Noninvasive methods to detect microstructural changes in collagen-based fibrous tissues are necessary to differentiate healthy from damaged tissues...
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Voxel-Wise Fusion of 3T and 7T Diffusion MRI Data to Extract more Accurate Fiber Orientations
While 7T diffusion magnetic resonance imaging (dMRI) has high spatial resolution, its diffusion imaging quality is usually affected by signal loss...
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The Effect of Nucleo-Olivary Stimulation on Climbing Fiber EPSPs in Purkinje Cells
Climbing fibers, connecting the inferior olive and Purkinje cells, form the nervous system's strongest neural connection. These fibers activate after...
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Development of associational fiber tracts in fetal human brain: a cadaveric laboratory investigation
The advent of diffusion tensor imaging (DTI) in addition to cadaveric brain dissection allowed a comprehensive description of an adult human brain....
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Brain white matter microstructural alterations in patients with systemic lupus erythematosus: an automated fiber quantification study
This study aimed to identify damaged segments of brain white matter fiber tracts in patients with systemic lupus erythematosus (SLE) using diffusion...
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A Fiber-Optic Scanner for Determining the Morphometric Parameters of the Palate in Patients
A new optical method is proposed for determining the size and configuration of the palate in patients with maxillofacial pathology by measuring the...
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Additional fiber orientations in the sagittal stratum—noise or anatomical fine structure?
The sagittal stratum is a prominent and macroscopically clearly visible white-matter structure within occipital and parietal lobes with a highly...
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Computational Analysis of the Effects of Fiber Deformation on the Microstructure and Permeability of Blood Oxygenator Bundles
Mechanical loads on the polymeric fibers of oxygenating bundles are commonly present due to bundle press-fitting during device assembly and blood...
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Restoring a Loss of Mossy Fiber Plasticity in a Model of Fragile X Syndrome
Fragile X Syndrome is a monogenic disorder that reflects a loss of Fragile X Mental Retardation Protein (FMRP) that is needed to regulate translation... -
Assessing the impact of extracellular matrix fiber orientation on breast cancer cellular metabolism
The extracellular matrix (ECM) is a dynamic and complex microenvironment that modulates cell behavior and cell fate. Changes in ECM composition and...
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Micromachined Optical Fiber Sensors for Biomedical Applications
Optical fibers revolutionized the rate of information reception and transmission in telecommunications. The revolution has now extended to the field... -
Aberrant white matter microstructure evaluation by automated fiber quantification in typhoon-related post-traumatic stress disorder
Super typhoons can lead to post-traumatic stress disorder (PTSD), which can adversely affect a person’s mental health after a disaster. Neuroimaging...
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Microbiota responses to different prebiotics are conserved within individuals and associated with habitual fiber intake
BackgroundShort-chain fatty acids (SCFAs) derived from gut bacteria are associated with protective roles in diseases ranging from obesity to...