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Ocular Drug Delivery: a Comprehensive Review
The human eye is a sophisticated organ with distinctive anatomy and physiology that hinders the passage of drugs into targeted ophthalmic sites....
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Role of Block Copolymers in Ocular Drug Delivery
For the therapeutic management of eye disorders, ophthalmic drug delivery is an important concern. Conventional drug delivery frequently possesses...
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Chitosan-Based Gels for Ocular Drug Delivery
Ocular drug delivery presents challenges to researchers due to the complexity of the eye as an organ. Different layers of barriers and other...
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Ocular barriers as a double-edged sword: preventing and facilitating drug delivery to the retina
In recent decades, the growing of the aging population in the world brings increasingly heavy burden of vision-threatening retinal diseases. One of...
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Light-responsive biomaterials for ocular drug delivery
Light-responsive biomaterials can be used for the delivery of therapeutic drugs and nucleic acids, where the tunable/precise delivery of payload...
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Ophthalmic and Otic Drug Delivery
This chapter introduces special considerations and formulation techniques for ophthalmic and otic drug delivery. Types of ophthalmic dosage forms are...
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Oleogels for the ocular delivery of epalrestat: formulation, in vitro, in ovo, ex vivo and in vivo evaluation
The ocular administration of lipophilic and labile drugs such as epalrestat, an aldose reductase inhibitor with potential for diabetic retinopathy...
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Construction and Evaluation of Hyaluronic Acid–Coated Flurbiprofen-Layered Double Hydroxide Ocular Drug Delivery System
In this study, flurbiprofen (FB) was selected as the model drug, and hyaluronic acid–coated flurbiprofen-layered double hydroxide ophthalmic drug...
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Nano-Based Drug Delivery Systems
Nanoparticles are important for refining drug delivery. There has been a considerable increase in the number of new biotechnology-based therapeutics....
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Unlocking the Potential of Bilosomes and Modified Bilosomes: a Comprehensive Journey into Advanced Drug Delivery Trends
Vesicular drug delivery systems have revolutionized the pharmaceutical field, offering a promising path for achieving targeted and sustained drug...
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Trends in Formulation Approaches for Sustained Drug Delivery to the Posterior Segment of the Eye
The eye, an intricate organ comprising physical and physiological barriers, poses a significant challenge for ophthalmic physicians seeking to treat...
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Prolonged Release Niosomes For Ocular Delivery of Loteprednol: Ocular Distribution Assessment on Dry Eye Disease Induced Rabbit Model
Loteprednol etabonate (LE) is a topical corticosteroid for the symptomatic management of ocular conditions, encompassing both allergic and infectious...
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Routes of Nano-drug Administration and Nano-based Drug Delivery System and Toxicity
In recent years, nanotechnology has grown significantly with enormous potential in technology in research and medicine to improve tissue engineering,...
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Drug Delivery in Biotechnology: Present and Future
Nanobiotechnology is the integration of nanotechnology with biotechnology, with a specific emphasis on the utilisation of nanoscale techniques in...
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Ocular Fluid Mechanics and Drug Delivery: A Review of Mathematical and Computational Models
The human eye is a complex biomechanical structure with a range of biomechanical processes involved in various physiological as well as pathological...
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Nanotechnology in Ocular Drug Delivery
The nano drug delivery system has already entered into the market for commercialization and so it is dynamically studied for the administration of a...
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Biomaterials for Controlled Drug Delivery Applications
A drug delivery system (DDS) is by definition a platform that can transfer a therapeutic agent to the disease site in order to elicit and improve the...
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Coloaded Surface–Modified PLGA Nanoparticles for Sustained Ocular Delivery of Levofloxacin and Flurbiprofen
PurposeThe purpose of the present work was to develop levofloxacin-flurbiprofen coloaded PLGA (LEV-FLU-PLGA) nanoparticles with surface modification...
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Nano-composite system of traditional Chinese medicine for ocular applications: molecular docking and three-dimensional modeling insight for intelligent drug evaluation
The absorption of drugs was impeded in the posterior part of the eye due to the special structure. In addition, it was crucial to comprehend...
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The Development and Evaluation of Phase Transition Microemulsion for Ocular Delivery of Acetazolamide for Glaucoma Treatment
The aim of this study was to develop microemulsion (ME) formulation with possible phase transition into liquid crystals upon ocular application to...
