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Long Non-coding RNAs in Cancer
Long non-coding RNAs (lncRNAs) are emerging as cardinal biomarkers for diagnosis, prognosis, and therapy of cancers as well as precise therapeutic...
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Non-coding RNAs in disease: from mechanisms to therapeutics
Non-coding RNAs (ncRNAs) are a heterogeneous group of transcripts that, by definition, are not translated into proteins. Since their discovery,...
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Non-coding RNAs and Exosomal Non-coding RNAs in Traumatic Brain Injury: the Small Player with Big Actions
Nowadays, there is an increasing concern regarding traumatic brain injury (TBI) worldwide since substantial morbidity is observed after it, and the...
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The Role of Non-coding RNAs in Cerebellar Development
Since the sequencing of the human and various mammalian genomes, it is clear that there are far too few protein-coding genes to specify and...
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Targeting and engineering long non-coding RNAs for cancer therapy
RNA therapeutics (RNATx) aim to treat diseases, including cancer, by targeting or employing RNA molecules for therapeutic purposes. Amongst the most...
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Modulation of Long Non-coding RNAs in Cancer
Cancer is associated to uncontrolled growth of cells. It is the second most common cause of death worldwide. Main treatment consists of surgery,...
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Long Non-coding RNAs in Cancer
Long non-coding RNAs (lncRNAs) are emerging as cardinal biomarkers for diagnosis, prognosis, and therapy of cancers as well as precise therapeutic...
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Role of non-coding RNAs in neuroblastoma
Neuroblastoma is known as the most prevalent extracranial malignancy in childhood with a neural crest origin. It has been widely accepted that...
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G-quadruplexes from non-coding RNAs
Non-coding RNAs (ncRNAs) are significant regulators of gene expression in a wide range of biological processes, such as transcription, RNA...
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MicroRNAs and Long Non-coding RNAs as Key Targets
Cancer is a potentially fatal and complex genetic disease characterized by the dysregulation of genome stability and cell proliferation, cell...
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Non-coding RNAs as skin disease biomarkers, molecular signatures, and therapeutic targets
Non-coding RNAs (ncRNAs) are emerging as biomarkers, molecular signatures, and therapeutic tools and targets for diseases. In this review, we focus...
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MicroRNAs and long non-coding RNAs during transcriptional regulation and latency of HIV and HTLV
Human immunodeficiency virus (HIV) and human T cell leukemia virus (HTLV) have replicative and latent stages of infection. The status of the viruses...
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Metabolism-regulating non-coding RNAs in breast cancer: roles, mechanisms and clinical applications
Breast cancer is one of the most common malignancies that pose a serious threat to women's health. Reprogramming of energy metabolism is a major...
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Alterations of mRNAs and Non-coding RNAs Associated with Neuroinflammation in Alzheimer’s Disease
Alzheimer’s disease is a neurodegenerative pathology whose pathognomonic hallmarks are increased generation of β-amyloid (Aβ) peptide, production of...
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Non-coding RNAs and Aquaporin 4: Their Role in the Pathogenesis of Neurological Disorders
Neurological disorders are a major group of non-communicable diseases affecting quality of life. Non-Coding RNAs (ncRNAs) have an important role in...
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The Potential of Targeting Autophagy-Related Non-coding RNAs in the Treatment of Alzheimer’s and Parkinson’s Diseases
Clearance of accumulated protein aggregates is one of the functions of autophagy. Recently, a clearer understanding of non-coding RNAs (ncRNAs)...
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Non-coding RNAs regulating mitochondrial function in cardiovascular diseases
Cardiovascular disease (CVD) is the leading cause of disease-related death worldwide and a significant obstacle to improving patients’ health and...
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Non-coding RNAs as potential therapeutic targets for receptor tyrosine kinase signaling in solid tumors: current status and future directions
This review article presents an in-depth analysis of the current state of research on receptor tyrosine kinase regulatory non-coding RNAs (RTK-RNAs)...
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Non-coding RNAs/DNMT3B axis in human cancers: from pathogenesis to clinical significance
Cancer is a complex disease with many contributing factors, and researchers have gained extensive knowledge that has helped them understand the...
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The Role of Non-coding RNAs in Drug Resistance of Cancers
Cancer is a leading cause of mortality in patients worldwide. Some types of cancer treatment are surgery, chemotherapy, radiation therapy, targeted...