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1. N6-methyladenosine methylation in kidney injury

   Multiple mechanisms are involved in kidney damage, among which the role of epigenetic modifications in the occurrence and development of kidney...

   Qimeng Wang, **aoting Fan, ... Rong Wang in Clinical Epigenetics

   Article Open access 21 October 2023
   

2. RNA N6-methyladenosine (m6A) modification in HNSCC: molecular mechanism and therapeutic potential

   Head and neck squamous cell carcinoma ranks seventh in incidence of malignant tumours in the world. Although there are treatments including surgery,...

   **nyu Sun, Shengqiao Fu, ... Hanqiang Lu in Cancer Gene Therapy

   Article 23 May 2023
   

3. Manipulating the tumour immune microenvironment by N6-methyladenosine RNA modification

   N6-methyladenosine (m6A), a posttranscriptional regulatory mechanism, is the most common epigenetic modification in mammalian mRNA. M6A modifications...

   **nyu Sun, Huirong Wang, ... Hanqiang Lu in Cancer Gene Therapy

   Article 04 June 2024
   

4. N6-Methyladenosine Methylation of mRNA in Cell Apoptosis

   Apoptosis, a highly controlled homeostatic mechanism that eliminates single cells without destroying tissue function, occurs during growing...

   Lin Zhang, Jian **a in Molecular Neurobiology

   Article 02 December 2023
   

5. Method for the Enrichment of N6-Methyladenosine-Modified Cellular and HIV-1 RNA

   N6-methyladenosine (m6A) modification of RNA is an important area in studying viral replication, cellular responses, and host immunity. HIV-1 RNA...

   Tarun Mishra, Stacia Phillips, Li Wu in HIV Protocols

   Protocol 2024
   

6. New horizons for the role of RNA N6-methyladenosine modification in hepatocellular carcinoma

   Hepatocellular carcinoma (HCC) is one of the most common malignancy, presenting a formidable challenge to the medical community owing to its...

   Yu-jia Li, Yang-ling Qiu, ... Shi-zhong Zheng in Acta Pharmacologica Sinica

   Article 09 January 2024
   

7. Targeting RNA N6-methyladenosine to synergize with immune checkpoint therapy

   Cancer immunotherapy, especially immune checkpoint therapy, has revolutionized therapeutic options by reactivating the host immune system. However,...

   **anyong Zhou, Chen Li, ... Qifeng Yang in Molecular Cancer

   Article Open access 21 February 2023
   

8. The biological function of the N6-Methyladenosine reader YTHDC2 and its role in diseases

   N6-methyladenosine (m6A) stands as the most prevalent modified form of RNA in eukaryotes, pivotal in various biological processes such as regulating...

   Xudong Wu, Hui Chen, ... Haoyu Tan in Journal of Translational Medicine

   Article Open access 24 May 2024
   

9. Regulatory roles of N6-methyladenosine (m⁶A) methylation in RNA processing and non-communicable diseases

   Post-transcriptional RNA modification is an emerging epigenetic control mechanism in cells that is important in many different cellular and...

   Faiz Ali Khan, Bernard Nsengimana, ... **gcheng Dong in Cancer Gene Therapy

   Article 05 June 2024
   

10. N6-methyladenosine modified lncRNAs signature for stratification of biochemical recurrence in prostate cancer

    Nonmutational epigenetic reprogramming is a crucial mechanism contributing to the pronounced heterogeneity of prostate cancer (PCa). Among these...

    Yingke Liang, Wenjun Yin, ... Jianming Lu in Human Genetics

    Article 27 September 2023
    

11. N6-methyladenosine and Neurological Diseases

    N6-methyladenosine (m6A) is a dynamic reversible methylation modification of the adenosine N6 position and is the most common chemical epigenetic...

    Nan Zhang, Chunhong Ding, ... Lielian Zuo in Molecular Neurobiology

    Article 15 January 2022
    

12. N6-methyladenosine-modified circPLPP4 sustains cisplatin resistance in ovarian cancer cells via PIK3R1 upregulation

    Background

    Cisplatin (CDDP) is the first-line chemotherapeutic strategy to treat patients with ovarian cancer (OC). The development of CDDP resistance...

    Han Li, Run Lin, ... Wei**g Zhang in Molecular Cancer

    Article Open access 06 January 2024
    

13. Functions of N6-methyladenosine in cancer metabolism: from mechanism to targeted therapy

    N6-methyladenosine (m6A) is the most abundant modification of eukaryotic mRNA and is involved in almost every stage of RNA metabolism. The m6A...

    Jiayi He, Furong Liu, Zhanguo Zhang in Biomarker Research

    Article Open access 13 April 2023
    

14. N6-methyladenosine modification positively regulate Japanese encephalitis virus replication

    N6-methyladenosine (m6A) is present in diverse viral RNA and plays important regulatory roles in virus replication and host antiviral innate...

    Min Yao, Zhirong Cheng, ... **n Lv in Virology Journal

    Article Open access 19 January 2024
    

15. The roles of N6-methyladenosine and its target regulatory noncoding RNAs in tumors: classification, mechanisms, and potential therapeutic implications

    N6-methyladenosine (m6A) is one of the epigenetic modifications of RNA. The addition of this chemical mark to RNA molecules regulates gene expression...

    Ziying Liu, Lei Gao, ... Qiushi Tang in Experimental & Molecular Medicine

    Article Open access 01 March 2023
    

16. Deficiency of N6-Methyladenosine Demethylase ALKBH5 Alleviates Ultraviolet B Radiation-Induced Chronic Actinic Dermatitis via Regulating Pyroptosis

    Pyroptosis is an inflammatory programmed cell death (PCD) and is reported to be associated with N6-methyladenosine (m6A) modification. This study...

    Li He, Lan Liu, ... **ang Nong in Inflammation

    Article 23 September 2023
    

17. Chidamide inhibits cell glycolysis in acute myeloid leukemia by decreasing N6-methyladenosine-related GNAS-AS1

    Background

    Acute myeloid leukemia (AML) is a hematopoietic malignancy. Chidamide has shown anti-cancer effect in different malignancies. The function...

    Changmei Hu, **ao Fu, ... Jie Peng in DARU Journal of Pharmaceutical Sciences

    Article 06 November 2023
    

18. N6-Methyladenosine Methylation of mRNA in Cell Senescence

    Cell senescence is the growth arrest caused by the accumulation of irreparable cell damage, which is involved in physiological and pathological...

    Lin Zhang, Jian **a in Cellular and Molecular Neurobiology

    Article 12 November 2021
    

19. N6-Methyladenosine RNA Modification in Normal and Malignant Hematopoiesis

    Over 170 nucleotide variants have been discovered in messenger RNAs (mRNAs) and non-coding RNAs so far. However, only a few of them, including...

    Hengyou Weng, Huilin Huang, Jianjun Chen in Hematopoietic Stem Cells

    Chapter 2023
    

20. N6-methyladenosine-related single-nucleotide polymorphism analyses identify oncogene RNFT2 in bladder cancer

    Background

    Single-nucleotide polymorphisms (SNPs) in N6-methyladenosine (m6A) related genetic locus play significant roles in tumorigenesis and...

    Jiancheng Lv, Qiang Song, ... Qiang Lu in Cancer Cell International

    Article Open access 05 October 2022