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Evaluation of an eight marker-panel including long mononucleotide repeat markers to detect microsatellite instability in colorectal, gastric, and endometrial cancers
BackgroundAccurate determination of microsatellite instability (MSI) status is critical for optimal treatment in cancer patients. Conventional MSI...
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Investigation of ENO2 as a promising novel marker for the progression of colorectal cancer with microsatellite instability-high
BackgroundMicrosatellite instability-high (MSI-H) has emerged as a significant biological characteristic of colorectal cancer (CRC). Studies reported...
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Assessment of Microsatellite Instability from Next-Generation Sequencing Data
Microsatellite instability (MSI) is a genetic alteration due to a deficiency of the DNA mismatch repair system, where microsatellites accumulate...
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Microsatellite markers for Opisthorchis felineus to understand its genetic diversity and transmission patterns of opisthorchiosis
Opisthorchis felineus is a food-borne trematode which causes opisthorchiosis and affects mainly the liver and bile ducts of the liver with a possible...
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Detection of (pre)cancerous colorectal lesions in Lynch syndrome patients by microsatellite instability liquid biopsy
Lynch syndrome (LS) is an inherited condition characterized by an increased risk of develo** cancer, in particular colorectal cancer (CRC)....
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Is GRA6 Gene a Suitable Marker for Molecular Ty** of Toxoplasma Gondii? A Sco** Systematic Review
Toxoplasmosis is a zoonotic disease with a worldwide prevalence that is caused by Toxoplasma gondii . This study aimed to summarize available data on...
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Comparison of standard mismatch repair deficiency and microsatellite instability tests in a large cancer series
BackgroundThe tumor-agnostic indication of immune checkpoint inhibitors to treat cancers with mismatch repair deficiency (dMMR)/microsatellite...
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Characterization of polymorphic microsatellite markers for the Japanese endangered land snail Mandarina
ObjectiveMandarina is an endangered land snail genus of the oceanic Ogasawara archipelago. On Chichijima Island, the largest inhabited island in...
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Genetic Diversity and Fine-Scale Population Structure Analysis of the Placocheilus cryptonemus in the Nujiang River from mtDNA and Microsatellite Markers
AbstractThe Nujiang River is rich in aquatic biodiversity, especially endemic fish. However, long-term human interference, such as cascade hydropower...
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First-line oxaliplatin-based chemotherapy and nivolumab for metastatic microsatellite-stable colorectal cancer—the randomised METIMMOX trial
BackgroundWe evaluated first-line treatment of metastatic microsatellite-stable colorectal cancer with short-course oxaliplatin-based chemotherapy...
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Identification of Hybrid Specimens of Rock Lizards Darevskia armeniaca × Darevskia valentini Based on Microsatellite Genoty**
The paper presents the results of the microsatellite genoty** of hybrid lizards D. armeniaca × D. valentini from sympatric populations of Armenia....
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Multiple-instance learning of somatic mutations for the classification of tumour type and the prediction of microsatellite status
Large-scale genomic data are well suited to analysis by deep learning algorithms. However, for many genomic datasets, labels are at the level of the...
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The genetic diversity of Oncomelania hupensis robertsoni, intermediate hosts of Schistosoma japonicum in hilly regions of China, using microsatellite markers
BackgroundThe elimination of schistosomiasis remains a challenging task, with current measures primarily focused on the monitoring and control of Onco...
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Association between c-type lectin-like receptor 2 and microsatellite instability in colorectal cancer: a cross-sectional study
BackgroundAs a transmembrane protein, C-type lectin-like receptor 2 (CLEC-2) is mainly expressed on platelets and released into plasma after platelet...
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A ring trial to harmonize Toxoplasma gondii microsatellite ty**: comparative analysis of results and recommendations for optimization
A ring trial among five European laboratories was organized to reach consistency in microsatellite (MS) ty** of the zoonotic parasite Toxoplasma...
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Differentiation of Juniperus deltoidеs R.P. Аdams in the Crimean-Caucasian Region according to the Variability of Microsatellite DNA Markers
AbstractThe structure of genetic variability of the prickly juniper Juniperus deltoides R.P. Adams (family Cupressaceae), an important component of...
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Gene S-phase kinase associated protein 2 is a novel prognostic marker in human neoplasms
BackgroundNeoplasms are a series of diseases affecting human health. Prognostic and tumor status–related markers for various tumors should be...
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Informative Relevance of 11 Microsatellite Loci for Forensic DNA Identification of Wild and Farm American Mink (Mustela vison) in Belarus
AbstractAmerican mink is involved in the economic activity of the Republic of Belarus since it belongs to resource hunting species as well as breeds...
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Development of microsatellite markers for population genetics of biting midges and a potential tool for species identification of Culicoides sonorensis Wirth & Jones
BackgroundProper vector surveillance relies on the ability to identify species of interest accurately and efficiently, though this can be difficult...
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Microsatellite instability assessment is instrumental for Predictive, Preventive and Personalised Medicine: status quo and outlook
A form of genomic alteration called microsatellite instability (MSI) occurs in a class of tandem repeats (TRs) called microsatellites (MSs) or short...
