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miRNA Dysregulation in Schizophrenia
Schizophrenia is a complex neuropsychiatric disorder that alters synapse activity as well as neural circuits. An intricate intracellular network of...
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Quantum MiRNA Code
The C. elegans’s lin-4 discovery in 1993 to date are still limited to C. elegans-specific RNA interference. The function of microRNA (miRNA) is based...
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MiRNA Immunity Against Virus and MiRNA Surveillance Against Tumor
Through the microRNA (miRNA) entangling target sorting/quantum miRNA language plus artificial intelligence (METS/MIRAI) analysis so far, it seems...
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Oxford miRNA Gardener
Genetic traits are a curious question for biological research to elucidate the etiology of pathogenesis and are transmitted from cell to cell,...
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Programmed Evolution by miRNA Memory
Diseases are deeply implicated in the aberrant expression of microRNA (miRNA) genes. The RNA Wave 2000 dogma consists of four criteria, as first...
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Exosomal miRNA-146a and miRNA-424 as Possible Predictors of Immune Checkpoint Inhibitors Therapy Response in Clear Cell Renal Cell Carcinoma
AbstractClear cell renal cell carcinoma (ccRCC) is a malignant kidney tumour with a poor prognosis and difficult to treat. Despite significant...
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Experimental capture of miRNA targetomes: disease-specific 3′UTR library-based miRNA targetomics for Parkinson’s disease
The identification of targetomes remains a challenge given the pleiotropic effect of miRNAs, the limited effects of miRNAs on individual targets, and...
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Evaluation of miRNA-16–2-3P, miRNA-618 levels and their diagnostic and prognostic value in the regulation of immune response during SARS Cov-2 infection
Following the announcement of the pandemic of COVID-19 in December 2019, several studies focused on how to early predict the severity of the disease...
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Trimethylamine-N-oxide, a New Risk Factor for Non-alcoholic Fatty Liver Disease Changes the Expression of miRNA-34a, and miRNA-122 in the Fatty Liver Cell Model
Non-alcoholic fatty liver disease is a multifactorial disorder with complicated pathophysiology ranging from simple steatosis to steatohepatitis and...
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Targeting miRNA and using miRNA as potential therapeutic options to bypass resistance in pancreatic ductal adenocarcinoma
Pancreatic ductal adenocarcinoma (PDAC) is a highly aggressive disease with poor prognosis due to early metastasis, low diagnostic rates at early...
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RNA-binding proteins and exoribonucleases modulating miRNA in cancer: the enemy within
Recent progress in the investigation of microRNA (miRNA) biogenesis and the miRNA processing machinery has revealed previously unknown roles of...
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Altered expression of serum lncRNA CASC2 and miRNA-21-5p in COVID-19 patients
Infection by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that causes coronavirus disease 2019 (COVID-19) has a high incidence of...
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Plasma-derived exosomal miRNA profiles reveal potential epigenetic pathogenesis of premature ovarian failure
The role of plasma-derived exosomal miRNA in premature ovarian failure (POF) remains unclear. This study aimed to investigate the epigenetic...
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Integrated Analysis of miRNA and mRNA Regulation Network in Hypertension
Hypertension is the most common chronic disease. Early diagnosis is helpful for early medical intervention. The miRNAs and the messenger RNAs (mRNAs)...
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Identification of miRNA expression profile in middle ear cholesteatoma using small RNA-sequencing
BackgroundThe present study aims to identify the differential miRNA expression profile in middle ear cholesteatoma and explore their potential roles...
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Identification of miRNA-Target Gene-Transcription Factor Regulatory Network as Functional Motifs Involved in Glomerular Diabetic Nephropathy
AbstractThe gene regulatory approach based on retrieving information from the database provides a detailed characterization of the molecular...
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The Concept of “Virus” Is the Same as Exosomal miRNA Gene
Virus is not the Latin word for “virus,” which means simply slimy liquid or poison. In the early twentieth century, viruses were referred to as...
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Phytochemicals and miRNA-Based Therapeutic Opportunities for Cancer Stem Cell-Mediated Tumor Angiogenesis
Cancer stem cell (CSC) is a small subset of cancer cell population with unique ability to self-renew. They are responsible for invasion and...
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Systems genetics identifies miRNA-mediated regulation of host response in COVID-19
BackgroundIndividuals infected with SARS-CoV-2 vary greatly in their disease severity, ranging from asymptomatic infection to severe disease. The...
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A novel 3-miRNA network regulates tumour progression in oral squamous cell carcinoma
BackgroundLate diagnosis is one of the major confounders in oral squamous cell carcinoma (OSCC). Despite recent advances in molecular diagnostics, no...
