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Transcriptomic profiling of long non-coding RNAs and messenger RNAs in the liver of mice during Toxoplasma gondii infection
BackgroundToxoplasma gondii is an intracellular protozoan parasite that can infect a wide range of warm-blooded animals, including humans. It poses...
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Role of the RNA-binding protein ZC3H41 in the regulation of ribosomal protein messenger RNAs in trypanosomes
BackgroundTrypanosomes are single-celled eukaryotes that rely heavily on post-transcriptional mechanisms to regulate gene expression. RNA-binding...
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of Potential Noncoding RNAs Related to Spinal Cord Injury Based on Competing Endogenous RNAs
This study aims to elucidate the key regulatory molecules, specifically messenger RNAs (mRNAs), long noncoding RNAs (lncRNAs), and microRNAs (miRNAs)...
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Temporal transcriptomic changes in long non-coding RNAs and messenger RNAs involved in the host immune and metabolic response during Toxoplasma gondii lytic cycle
BackgroundLong non-coding RNAs (lncRNAs) are important regulators of various biological and pathological processes, in particular the inflammatory...
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Optimal design of synthetic circular RNAs
Circular RNAs are an unusual class of single-stranded RNAs whose ends are covalently linked via back-splicing. Due to their versatility, the need to...
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Posttranscriptional Regulation by Proteins and Noncoding RNAs
Posttranscriptional regulation comprises those mechanisms occurring after the initial copy of the DNA sequence is transcribed into an intermediate...
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Long Non-coding RNAs in Cancer
Long non-coding RNAs (lncRNAs) are emerging as cardinal biomarkers for diagnosis, prognosis, and therapy of cancers as well as precise therapeutic...
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Epigenetics and Circular RNAs in Cancer
Circular RNAs (circRNAs) are a class of non-coding RNAs in cells that lack a 5-terminal cap and a 3-terminal poly-A tail. These covalently closed RNA...
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Transfer RNAs as dynamic and critical regulators of cancer progression
Transfer RNAs (tRNAs) have been historically viewed as non-dynamic adaptors that decode the genetic code into proteins. Recent work has uncovered...
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Long Non-coding RNAs in Cancer
Long non-coding RNAs (lncRNAs) are emerging as cardinal biomarkers for diagnosis, prognosis, and therapy of cancers as well as precise therapeutic...
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Non-coding RNAs and Exosomal Non-coding RNAs in Traumatic Brain Injury: the Small Player with Big Actions
Nowadays, there is an increasing concern regarding traumatic brain injury (TBI) worldwide since substantial morbidity is observed after it, and the...
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Competing Endogenous RNAs Crosstalk in Hippocampus: A Potential Mechanism for Neuronal Develo** Defects in Down Syndrome
Down syndrome (DS) is the most example of aneuploidy, resulting from an additional copy of all or part of chromosome 21. Competing endogenous RNAs...
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Alterations of mRNAs and Non-coding RNAs Associated with Neuroinflammation in Alzheimer’s Disease
Alzheimer’s disease is a neurodegenerative pathology whose pathognomonic hallmarks are increased generation of β-amyloid (Aβ) peptide, production of...
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Circular RNAs in renal cell carcinoma: from mechanistic to clinical perspective
CircRNAs, a special type of noncoding RNAs characterized by their stable structure and unique abilities to form backsplicing loops, have recently...
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Non-coding RNAs as skin disease biomarkers, molecular signatures, and therapeutic targets
Non-coding RNAs (ncRNAs) are emerging as biomarkers, molecular signatures, and therapeutic tools and targets for diseases. In this review, we focus...
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Exosomal microRNAs and long noncoding RNAs: as novel biomarkers for endometriosis
Endometriosis is a gynecological inflammatory disorder characterized by the development of endometrial-like cells outside the uterine cavity. This...
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Role of non-coding RNAs in neuroblastoma
Neuroblastoma is known as the most prevalent extracranial malignancy in childhood with a neural crest origin. It has been widely accepted that...
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Non-coding RNAs as potential therapeutic targets for receptor tyrosine kinase signaling in solid tumors: current status and future directions
This review article presents an in-depth analysis of the current state of research on receptor tyrosine kinase regulatory non-coding RNAs (RTK-RNAs)...
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Non-coding RNAs and Aquaporin 4: Their Role in the Pathogenesis of Neurological Disorders
Neurological disorders are a major group of non-communicable diseases affecting quality of life. Non-Coding RNAs (ncRNAs) have an important role in...
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Clinical Utility of Noncoding RNAs as Systemic Biomarkers in Animal Models
Noncoding RNAs are the RNAs that do not encode for proteins, yet play a vital role in various cellular processes. Compelling cancer research evidence...