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Reproductive and Social Policies, Sociopolitical Stress, and Implications for Maternal and Child Health Equity
Purpose of ReviewAlthough many environmental exposures (e.g., air pollution) are geographically patterned and persist as a result of historic...
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Improving behavioral deficits induced by perinatal ethanol and stress exposure in adolescent male rat progeny via maternal melatonin treatment
Background and aimEarly-life stressful situations and binge drinking have been thus far acknowledged as two burdensome conditions that potentially...
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Maternal Recognition of Pregnancy
Hormone-induced adaptations occur in many aspects of maternal physiology during gestation. Before these changes can be initiated, the newly formed... -
Multi-scale Modelling of Shear Stress on the Syncytiotrophoblast: Could Maternal Blood Flow Impact Placental Function Across Gestation?
The placenta is a critical fetal exchange organ, with a complex branching tree-like structure. Its surface is covered by a single multinucleated...
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Neuroendocrine Control of Maternal Behavior
Maternal caregiving is an essential component of successful mammalian reproduction. Indeed, almost all mothers exhibit a species-typical repertoire... -
Maternal–fetal stress and DNA methylation signatures in neonatal saliva: an epigenome-wide association study
BackgroundMaternal stress before, during and after pregnancy has profound effects on the development and lifelong function of the infant’s...
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Gut microbiota contributes to bisphenol A-induced maternal intestinal and placental apoptosis, oxidative stress, and fetal growth restriction in pregnant ewe model by regulating gut-placental axis
BackgroundBisphenol A (BPA) is an environmental contaminant with endocrine-disrupting properties that induce fetal growth restriction (FGR). Previous...
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Protective effects of rosmarinic acid against autistic-like behaviors in a mouse model of maternal separation stress: behavioral and molecular amendments
Autism spectrum disorder (ASD) is a neurodevelopmental disorder with worldwide increasing incidence. Maternal separation (MS) stress at the beginning...
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The programming of kidney injury in offspring affected by maternal overweight and obesity: role of lipid accumulation, inflammation, oxidative stress, and fibrosis in the kidneys of offspring
Maternal overweight and obesity are considered important factors affecting fetal development with many potential consequences for offspring after...
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Effect of chronic maternal L-Glu intake during gestation and/or lactation on oxidative stress markers, AMPA Glu1 receptor and adenosine A1 signalling pathway from foetal and neonatal cerebellum
L-Glutamate (L-Glu) is an amino acid present in the diet that plays a fundamental role in the central nervous system, as the main excitatory...
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The Influence of Maternal Hypoxia and Buspirone during Pregnancy on Cognitive Abilities and a Stress Response in Adult Male Offspring
Spatial learning, memory, and reactivity of the hypothalamic—pituitary—adrenocortical system (HPA axis) were studied in adult male rats, whose...
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Feto-Maternal Interface Organ-on-Chip: A New Technology to Study Ascending Infection
Modeling human pregnancy is challenging as two subjects, the mother and fetus, must be evaluated in tandem. To understand pregnancy, parturition, and... -
Maternal adverse childhood experiences impact fetal adrenal volume in a sex-specific manner
BackgroundThe mechanisms by which parental early life stress can be transmitted to the next generation, in some cases in a sex-specific manner, are...
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Effects of omega-3 fatty acid supplementation during chronic maternal hypoxia on behavioral disorders in male rat offspring: the role of Trk family and oxidative stress
Maternal hypoxia due to a lack of blood flow and insufficient oxygen supply in the brain leads to behavioral disorders in adult offspring. Fish oil...
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Genome-wide neonatal epigenetic changes associated with maternal exposure to the COVID-19 pandemic
BackgroundDuring gestation, stressors to the fetus, including viral exposure or maternal psychological distress, can fundamentally alter the neonatal...
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Heat exposure induced risks of preterm birth mediated by maternal hypertension
Heat exposure is associated with an increased risk of preterm birth (PTB), with previous work suggesting that maternal blood pressure may play a role...
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Role of Maternal Immune Factors in Neuroimmunology of Brain Development
Inflammation during pregnancy may occur due to various factors. This condition, in which maternal immune system activation occurs, can affect fetal...
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Maternal physiological calming responses to infant suckling at the breast
The mother–infant relation is key to infant physical, cognitive and social development. Mutual regulation and cooperation are required to maintain...
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Maternal nutrition and effects on offspring vascular function
Maternal nutrition during pregnancy may have profound effects on the develo** fetus and impact risk for cardiovascular disease later in life. Here,...
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Maternal adverse childhood experiences (ACEs) and DNA methylation of newborns in cord blood
BackgroundAdverse childhood experiences (ACEs) increase the risk of poor health outcomes later in life. Psychosocial stressors may also have...