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Bluish-white Light-emitting 2D Sheets of Lead-free Perovskite Cesium Titanium Bromide (CsTiBr3) by a Two-stage Deposition Technique
Bluish-white light-emitting materials are commonly used in LED lighting because they produce natural-looking light. Here we report the...
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Exposure to lead-free frangible firing emissions containing copper and ultrafine particulates leads to increased oxidative stress in firing range instructors
BackgroundSince the introduction of copper based, lead-free frangible (LFF) ammunition to Air Force small arms firing ranges, instructors have...
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Binding Free Energy Calculation Using Quantum Mechanics Aimed for Drug Lead Optimization
The routine use of in silico tools is already established in drug lead design. Besides the use of molecular docking methods to screen large chemical...
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Defense Against Oxidative Stress: Nrf2-ARE Pathway
Reactive chemical intermediates, including reactive oxygen and nitrogen species and free radicals, are formed during foreign compound metabolic...
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Lead equivalence testing using a custom-built testing kit
Radiation protective garments should undergo a quality assurance regime comprising of an acceptance test of the lead equivalence before the garment...
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Exploring the anticancer potential of fluoro flavone analogues: insights from molecular docking and dynamics studies with Aurora Kinase B
Aurora Kinase B belongs to the serine kinase family. It plays an essential role in cell division and participates in mitosis and chromatid...
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Biomimetic Antidote Nanoparticles: a Novel Strategy for Chronic Heavy Metal Poisoning
Chronic lead poisoning has become a major factor in global public health. Chelation therapy is usually used to manage lead poisoning....
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Impact of Chronic Pain on Use-Dependent Plasticity: Corticomotor Excitability and Motor Representation in Musicians With and Without Pain
Long-term musical training induces adaptive changes in the functional representation of the motor cortex. It is unknown if the maladaptive plasticity...
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Induction of Labor at Term for Severe Antenatal Lead Poisoning
IntroductionAntenatal lead exposure is associated with multiple adverse maternal and fetal consequences. Maternal blood lead concentrations as low as...
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Integrating Computational Approaches to Predict the Effect of Genetic Variants on Protein Stability in Retinal Degenerative Disease
Protein function can be impacted by changes in protein structure stability, but determining which change has impact is complex. Stability can be...
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Epilepsy and Oxidative Stress
Epilepsy is one of the most common neurological condition reported worldwide. Oxidative stress and neuroinflammation have been strongly associated...
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Analysis of the Mechanisms of Impairment of Functional Parameters of Internal Organs in Saturnism in an Experiment in Rats
In rats with lead intoxication (intramuscular administration of lead acetate in a dose 5 mg/kg for 30 days), the development of oxidative stress,...
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Physiological and pathological effects of phase separation in the central nervous system
Phase separation, also known as biomolecule condensate, participates in physiological processes such as transcriptional regulation, signal...
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Effect of Environmental Stressors, Xenobiotics, and Oxidative Stress on Male Reproductive and Sexual Health
This article examines the environmental factor-induced oxidative stress (OS) and their effects on male reproductive and sexual health. There are...
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Enhancing Diagnostic Accuracy and Efficiency with GPT-4-Generated Structured Reports: A Comprehensive Study
PurposeInterpreting free-text contrast-enhanced ultrasound (CEUS) reports can lead to diagnostic errors and prolonged patient waiting times....
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Antioxidant Effects of Crataegus laevigata on Rat’s Brain under Hypobaric Hypoxia-Induced Oxygen Deficiency
AbstractAcute hypobaric hypoxia induces various pathological mechanisms that lead to the development of oxidative stress damaging the neurons of the...
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A journey to unravel the pathophysiology of stable and exacerbated Chronic Obstructive Pulmonary Disease through erythrocyte proteomics: a combined mass spectrometry/bioinformatics approach
Chronic Obstructive Pulmonary Disease (COPD) is a progressive lung disorder with high mortality. The present study explores the novel and highly...
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Diabetes Management: From “Painful” Pricks to “Pain-Free” Bliss
“Diabetes management” is a collective word given to various plans and measures taken in order to maintain glucose homeostasis. Hyperglycemia is one...
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Bile Acid–Targeted Hyaluronic Acid Nanoparticles for Enhanced Oral Absorption of Deferoxamine
Patients with β-thalassemia and sickle cell disease often rely on blood transfusions which can lead to hemochromatosis and chronic oxidative stress...
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Therapeutic Modalities Regarding ROS in Leukemia and Hematopoietic Stem/Progenitor Cell Perspective
Discovery of free radicals opened a new avenue in the world of science. Further studies revealed immensely impactful and diverse functions of free...