Search
Search Results
-
Diabetic Cardiomyopathy and Cell Death: Focus on Metal-Mediated Cell Death
Cardiac myocyte death is an essential initiator of the pathogenesis and progression of various etiological cardiomyopathies, including diabetic...
-
In diabetic male Wistar rats, quercetin-conjugated superparamagnetic iron oxide nanoparticles have an effect on the SIRT1/p66Shc-mediated pathway related to cognitive impairment
BackgroundQuercetin (QC) possesses a variety of health-promoting effects in pure and in conjugation with nanoparticles. Since the mRNA-SIRT1/p66Shc...
-
Disulfidptosis: A new type of cell death
Disulfidptosis is a novel form of cell death that is distinguishable from established programmed cell death pathways such as apoptosis, pyroptosis,...
-
Crosstalk Between Cell Death and Spinal Cord Injury: Neurology and Therapy
Spinal cord injury (SCI) often leads to neurological dysfunction, and neuronal cell death is one of the main causes of neurological dysfunction....
-
Cell Death-NO-Today: Effect of NO and RNS on Non-apoptotic Regulated Cell Death
Nitric oxide (NO), generated either enzymatically or non-enzymatically plays a significant role in cellular physiology. At low concentration, NO acts...
-
The therapeutic potential of targeting regulated non-apoptotic cell death
Cell death is critical for the development and homeostasis of almost all multicellular organisms. Moreover, its dysregulation leads to diverse...
-
Cell death by phagocytosis
Cells can die as a consequence of being phagocytosed by other cells — a form of cell death that has been called phagotrophy, cell cannibalism,...
-
Deferoxamine Prevents Neonatal Posthemorrhagic Hydrocephalus Through Choroid Plexus-Mediated Iron Clearance
Posthemorrhagic hydrocephalus occurs in up to 30% of infants with high-grade intraventricular hemorrhage and is associated with the worst...
-
Diversity and complexity of cell death: a historical review
Death is the inevitable fate of all living organisms, whether at the individual or cellular level. For a long time, cell death was believed to be an...
-
A matter of new life and cell death: programmed cell death in the mammalian ovary
BackgroundThe mammalian ovary is a unique organ that displays a distinctive feature of cyclic changes throughout the entire reproductive period. The...
-
Endolysosome iron restricts Tat-mediated HIV-1 LTR transactivation by increasing HIV-1 Tat oligomerization and β-catenin expression
HIV-1 transactivator of transcription (Tat) protein is required for HIV-1 replication, and it has been implicated in the pathogenesis of...
-
Regulated cell death pathways in cardiomyopathy
Heart disease is a worldwide health menace. Both intractable primary and secondary cardiomyopathies contribute to malignant cardiac dysfunction and...
-
Microglial ferroptotic stress causes non-cell autonomous neuronal death
BackgroundFerroptosis is a form of regulated cell death characterised by lipid peroxidation as the terminal endpoint and a requirement for iron....
-
Entosis: the core mechanism and crosstalk with other cell death programs
Cell death pathways play critical roles in organism development and homeostasis as well as in the pathogenesis of various diseases. While studies...
-
Involvement of histone methylation in the regulation of neuronal death
Neuronal death occurs in various physiological and pathological processes, and apoptosis, necrosis, and ferroptosis are three major forms of neuronal...
-
The significant mechanism and treatments of cell death in heatstroke
With global warming, extreme environmental heat is becoming a social issue of concern, which can cause adverse health results including heatstroke...
-
Crosstalk between metabolism and cell death in tumorigenesis
It is generally recognized that tumor cells proliferate more rapidly than normal cells. Due to such an abnormally rapid proliferation rate, cancer...
-
Melanoma biology and treatment: a review of novel regulated cell death-based approaches
The incidence of melanoma, the most lethal form of skin cancer, has increased due to ultraviolet exposure. The treatment of advanced melanoma,...
-
Mitochondria-associated programmed cell death as a therapeutic target for age-related disease
Mitochondria, ubiquitous double-membrane-bound organelles, regulate energy production, support cellular activities, harbor metabolic pathways, and,...
-
Extracellular Vesicles: Therapeutic Potential in Central Nervous System Trauma by Regulating Cell Death
CNS (central nervous system) trauma, which is classified as SCI (spinal cord injury) and TBI (traumatic brain injury), is gradually becoming a major...
