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The effect of maternal intravenous hydration on amniotic fluid index in oligohydramnios
ObjectiveAssessing amniotic fluid determines an important dimension of fetal health. Significant relationships of oligohydramnios, which occurs in...
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A temperature-responsive intravenous needle that irreversibly softens on insertion
The high stiffness of intravenous needles can cause tissue injury and increase the risk of transmission of blood-borne pathogens through accidental...
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Evaluation of GSK2789917-induced TRPV4 inhibition in animal models of fluid induced lung injury
Administration of bolus intravenous fluids, common in pre-hospital and hospitalised patients, is associated with increased lung vascular permeability...
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Hemorrhagic Activity of Cationic Starch Conjugates with Sterically Hindered Phenol after Intravenous Administration to Guinea Pigs
Intravenous injection of cationic starch conjugated with sterically hindered phenol (terpenophenol) to guinea pigs did not increase hemorrhagic...
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Synovial fluid and plasma concentrations of tedizolid in patients with osteoarthritis infected with Staphylococcus aureus effectively determined with fluorescence detection
BackgroundTedizolid is a new oxazolidinone antibiotic with high potency for the treatment of infections caused by methicillin-resistant Staphylococcus...
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Optimizing Antibiotic Therapy for Intravenous Drug Users: A Narrative Review Unraveling Pharmacokinetics/Pharmacodynamics Challenges
Intravenous drug users (IVDUs) face heightened susceptibility to life-threatening gram-positive bacterial infections, particularly...
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Cerebral Small Vessel Disease and Infarct Growth in Acute Ischemic Stroke Treated with Intravenous Thrombolysis
We investigated relations between cerebral small vessel disease (cSVD) markers and evolution of the ischemic tissue from ischemic core to final...
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Intravenous Alcohol Administration Studies in Humans: Investigator-Prescribed and Self-Administration Paradigms
Alcohol administration experiments, or sometimes termed alcohol challenges, fall into two classes: those in which the investigator determines the...
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Pharmacokinetics of a New Neuroprotector — Indenoquinoxalinone Derivative after Intravenous Administration in Rabbits and Rats
The specific JNK inhibitor and NO donor 11 H -indeno[1,2- b ]quinoxalin-11-one oxime (IQ-1) demonstrated pronounced neuroprotective properties in an in...
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Heroin use and neuropsychological impairments: comparison of intravenous and inhalational use
Background and objectivesInjection and inhalational heroin use are associated with different levels of brain exposure to heroin and its metabolites...
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Plasma and synovial fluid concentrations of linezolid in patients with knee osteoarthritis infected with Staphylococcus aureus
BackgroundLinezolid is a new oxazolidinone antibiotic used for infections caused by methicillin-resistant Staphylococcus and other species.
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Bolus intravenous 0.9% saline leads to interstitial permeability pulmonary edema in healthy volunteers
PurposeBolus intravenous administration of 0.9% saline has been associated with the development of pulmonary edema, and increased mortality. An...
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Intrauterine inflammation and postnatal intravenous dopamine alter the neurovascular unit in preterm newborn lambs
BackgroundIntrauterine inflammation is considered a major cause of brain injury in preterm infants, leading to long-term neurodevelopmental deficits....
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Lecture 21: Pressure and Fluid Dynamics
Pressure is the force (in N) being exerted, divided by the area (in m2) on which the force acts. Note that pressure is NOT a force (nor is it a...
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Population Pharmacokinetics and Dosing Simulations of Intravenous Oxycodone for Perioperative Pain Relief in Adult Surgical Patients with Obesity
Background and ObjectiveOxycodone, a semisynthetic thebaine derivative µ-opioid (MOP) receptor agonist, is effective for treating moderate and severe...
