Parenteral Route of Exposure (Intramuscular, Intravenous, Subcutaneous, Intradermal, Intracranial, Intraperitoneal)

There are many different ways to provide medications to lab animals. The route depends significantly on whether the medication is administered for a local, systemic, or parenteral impact. Because parenteral administration techniques stop the first-pass action of hepatic metabolism, which commonly happens with oral chemicals and pharmaceuticals, they usually result in the highest bioavailability of substances.

Parenteral techniques also help to reduce some of the uncertainty associated with enteral absorptive processes. Furthermore, depending on the study’s goal, regulatory restrictions could affect the choice of a certain method. Intravenous: The most effective way to provide chemicals to animals is intravenous since it does not need solute absorption. This technique involves the acute or continuous administration of drugs. Precision spring-operated disposable pumps that are less expensive have recently become available for this use and, depending on the nature of the substance to be...