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Immunochromatographic and microscopic detection of Plasmodium falciparum in recipients of P. falciparum-infected donor blood
Blood transfusion practice is an essential medical intervention; however, it poses problems of transmissibility of infectious diseases including...
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Exploring the global immune landscape of peripheral blood mononuclear cells in H5N6-infected patient with single-cell transcriptomics
BackgroundAvian influenza viruses (AIV), particularly H5N6, have risen in infection frequency, prompting major concerns. Single-cell RNA sequencing...
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Modeling HIV-1 Infection in CNS via Infected Monocytes Using Immunocompetent Brain Organoids
The development of 3D-organoid models has revolutionized the way diseases are studied. Recently, our brain organoid model has been shown to...
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Overcoming donor variability and risks associated with fecal microbiota transplants through bacteriophage-mediated treatments
BackgroundFecal microbiota transplantation (FMT) and fecal virome transplantation (FVT, sterile filtrated donor feces) have been effective in...
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Develo** Wolbachia-Infected Cell Lines from Insects
Wolbachia, an intracellular bacterium of arthropods, is an ideal candidate for use in the biological control of insect pests. The inability of...
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Molecular epidemiology of hepatitis B virus among HIV co-infected and mono-infected cohorts in Northwest Ethiopia
BackgroundHepatitis B virus (HBV) infection is a particular concern in human immunodeficiency virus (HIV) infected individuals. In Ethiopia, detailed...
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Human macrophages infected with Egyptian Rousette bat-isolated Marburg virus display inter-individual susceptibility and antiviral responsiveness
Marburg virus (MARV) is a highly pathogenic filovirus and a causative agent of sporadic zoonotic viral hemorrhagic fever outbreaks with high case...
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Vitamin C-rich juice co-administration with artemether-lumefantrine ameliorates oxido-inflammatory responses in Plasmodium berghei-infected mice
This study investigated the effects of co-administration of a commercial juice rich in vitamin C (Vit C) on the antimalarial efficacy of...
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Enhanced M-CSF/CSF1R Signaling Closely Associates with PrPSc Accumulation in the Scrapie-Infected Cell Line and the Brains of Scrapie-Infected Experimental Rodents
Activation and proliferation of microglia are one of the hallmarks of prion disease and is usually accompanied by increased levels of various...
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Profound phenotypic and epigenetic heterogeneity of the HIV-1-infected CD4+ T cell reservoir
Understanding the complexity of the long-lived HIV reservoir during antiretroviral therapy (ART) remains a considerable impediment in research...
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Macrophage phagocytosis of SARS-CoV-2-infected cells mediates potent plasmacytoid dendritic cell activation
Early and strong interferon type I (IFN-I) responses are usually associated with mild COVID-19 disease, whereas persistent or unregulated...
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Varicella-zoster virus proteome-wide T-cell screening demonstrates low prevalence of virus-specific CD8 T-cells in latently infected human trigeminal ganglia
BackgroundTrigeminal ganglia (TG) neurons are an important site of lifelong latent varicella-zoster virus (VZV) infection. Although VZV-specific...
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A Novel Fluoro-Pyrazine-Bridged Donor-Accepter-Donor Fluorescent Probe for Lipid Droplet-Specific Imaging in Diverse Cells and Superoxide Anion Generation
PurposeLipid droplets (LDs) are dynamic organelles which associated with many metabolic processes. Reliable long-term imaging of LD is of great...
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A shotgun metagenomic analysis of the fecal microbiome in humans infected with Giardia duodenalis
BackgroundThe mechanisms underlying the clinical outcome disparity during human infection with Giardia duodenalis are still unclear. In recent...
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Comparable anti-CMV responses of transplant donor and third-party CMV-specific T cells for treatment of CMV infection after allogeneic stem cell transplantation
Adoptive transfer of cytomegalovirus (CMV)-specific cytotoxic T lymphocytes (CMV-CTLs) from original transplant donors or third-party donors was...
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Antiplasmodial Activity of β-Ionone and the Effect of the Compound on Amelioration of Anaemia and Oxidative Organ Damage in Mice Infected with Plasmodium berghei
IntroductionOwing to evolution of parasite strains that are resistant to existing antimalarial drugs, research for novel antimalarial medicines is...
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Human Trypanosoma cruzi infection in the Argentinean Chaco: risk factors and identification of households with infected children for treatment
BackgroundChagas disease is a neglected tropical disease (NTD). Cost-effective strategies for large-scale implementation of diagnosis and etiological...
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Screening the Tissue Donor for Infectious Agents
Like all substances of human origin, tissues are capable of transmitting infectious agents from donor to recipient. The screeningScreening of tissue...
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Fast detection and quantification of Plasmodium species infected erythrocytes in a non-endemic region by using the Sysmex XN-31 analyzer
BackgroundDue to increased travel from endemic countries, malaria occurs more frequently in non-endemic regions. It is a challenge for diagnostic...
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High-carbohydrate diet lacked the potential to ameliorate parasitemia and oxidative stress in mice infected with Plasmodium berghei
The search for a novel prophylactic agent against malaria is on the rise due to the negative socio-economic impact of the disease in tropical and...
