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Immune Response
The specific reactivity induced by an antigenic stimulus in a host is known as an immune response. The immune system is developed in a host primarily... -
The Immune Response
The process of viral infection having been briefly described, it is important to present the mechanisms involved in the immune response of the... -
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Echinococcosis Immune Response, Immunopathogenesis and Immune Evasion from the Human Host
Echinococcosis is a worldwide parasitic disease with great harm and complicated immune mechanisms. Immunoprophylaxis is an ideal way to prevent... -
Evading the Antitumour Immune Response
The mutations that cause (or accompany) malignancy result in tumour cells being detected as “non-self” by the immune system and may evoke an... -
Immune Response to Staphylococcus aureus
Although Staphylococcus aureus is not a high virulent pathogen in healthy persons, this bacterium often persists in various tissues and mucosa and... -
Molluscum Contagiosum Virus: Biology and Immune Response
Molluscum contagiosumMolluscum contagiosum virus is a poxvirus belonging to the Poxviridae family, which includes Orthopoxvirus, Parapoxvirus,... -
RNA Metabolism Governs Immune Function and Response
Inflammation is a complex process that protects our body from various insults such as infection, injury, and stress. Proper inflammation is... -
Immune Checkpoint Blockade Response Biomarkers
Cancer immunotherapy based on immune checkpoint blockade (ICB) has demonstrated durable clinical benefit in patients with immunogenic tumors,... -
Soluble immune checkpoints: implications for cancer prognosis and response to immune checkpoint therapy and conventional therapies
Longitudinal sampling of tumor tissue from patients with solid cancers, aside from melanoma and a few other cases, is often unfeasible, and thus may...
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Olfactory immune response to SARS-CoV-2
Numerous pathogens can infect the olfactory tract, yet the pandemic caused by SARS-CoV-2 has strongly emphasized the importance of the olfactory...
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Immune response in influenza virus infection and modulation of immune injury by viral neuraminidase
Influenza A viruses cause severe respiratory illnesses in humans and animals. Overreaction of the innate immune response to influenza virus infection...
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An IFNγ-dependent immune–endocrine circuit lowers blood glucose to potentiate the innate antiviral immune response
Viral infection makes us feel sick as the immune system alters systemic metabolism to better fight the pathogen. The extent of these changes is...
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Macrophages coordinate immune response to laser-induced injury via extracellular traps
BackgroundRetinal degeneration results from disruptions in retinal homeostasis due to injury, disease, or aging and triggers peripheral leukocyte...
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Host Immune Response to Scabies
Scabies infection is associated with heightened total IgE immunoglobulin and IgE antibodies to scabies antigens, with both being extremely high for... -
Inhibition of autophagy-related protein 7 enhances anti-tumor immune response and improves efficacy of immune checkpoint blockade in microsatellite instability colorectal cancer
BackgroundThe efficacy of anti-PD-1 therapy is primarily hindered by the limited T-cell immune response rate and immune evasion capacity of tumor...
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Immune selection determines tumor antigenicity and influences response to checkpoint inhibitors
In cancer, evolutionary forces select for clones that evade the immune system. Here we analyzed >10,000 primary tumors and 356...
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The dengue-specific immune response and antibody identification with machine learning
Dengue virus poses a serious threat to global health and there is no specific therapeutic for it. Broadly neutralizing antibodies recognizing all...
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Choroid plexus immune cell response in murine hydrocephalus induced by intraventricular hemorrhage
BackgroundIntraventricular hemorrhage (IVH) and associated hydrocephalus are significant complications of intracerebral and subarachnoid hemorrhage....
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Novel insights into the immune response to bacterial T cell superantigens
Bacterial T cell superantigens (SAgs) are a family of microbial exotoxins that function to activate large numbers of T cells simultaneously. SAgs...