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Comparative study of the hemodynamic characteristics of artificial mechanical heart valves with one and three leaflets in the tricuspid position
We present here a comparative study of two designs of artificial heart valves (AHV)—with one and three leaflets respectively—in relation to the...
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Pathological hemodynamic changes and leukocyte transmigration disrupt the blood–spinal cord barrier after spinal cord injury
BackgroundBlood–spinal cord barrier (BSCB) disruption is a key event after spinal cord injury (SCI), which permits unfavorable blood-derived...
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Comparison of Hemodynamic Parameters of Bicuspid Artificial Heart Valves in the Mitral Position
Several models of bicuspid artificial heart valves and their hemodynamic characteristics in the mitral position were compared. The aim of this work...
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The Comparative Method Based on Coronary Computed Tomography Angiography for Assessing the Hemodynamic Significance of Coronary Artery Stenosis
PurposeAn important aspect in the prevention and treatment of coronary artery disease is the functional evaluation of narrowed blood vessels. Medical...
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Aortic Dissection is Determined by Specific Shape and Hemodynamic Interactions
The aim of this study was to determine whether specific three-dimensional aortic shape features, extracted via statistical shape analysis (SSA),...
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Aneurysm geometric features effect on the hemodynamic characteristics of blood flow in coronary artery: CFD simulation on CT angiography-based model
The main purpose of the present numerical study is to evaluate the influences of aneurysm geometric features on the hemodynamic conditions within the...
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An Anatomically Shaped Mitral Valve for Hemodynamic Testing
In vitro modeling of the left heart relies on accurately replicating the physiological conditions of the native heart. The targeted physiological...
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Hemodynamics During Development and Postnatal Life
A well-developed heart is essential for embryonic survival. There are constant interactions between cardiac tissue motion and blood flow, which... -
Investigating the Upstream and Downstream Hemodynamic Boundary Conditions of Healthy and Growth-Restricted Rat Feto-Placental Arterial Networks
The placenta uniquely develops to orchestrate maternal adaptations and support fetal growth and development. The expansion of the feto-placental...
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Numerical Study of a Thrombus Migration Risk in Aneurysm After Coil Embolization in Patient Cases: FSI Modelling
PurposeThere are still many challenges for modelling a thrombus migration process in aneurysms. The main novelty of the present research lies in the...
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Establishment of a Modular Hemodynamic Simulator for Accurate In Vitro Simulation of Physiological and Pathological Pressure Waveforms in Native and Bioartificial Blood Vessels
PurposeIn vitro stimulation of native and bioartificial vessels in perfusable systems simulating natural mechanical environments of the human...
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EDL Induced Electro-magnetized Modified Hybrid Nano-blood Circulation in an Endoscopic Fatty Charged Arterial Indented Tract
PurposeThe electrokinetic process for streaming fluids in magnetic environments is emerging due to its immense applications in medical and...
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Impact of Cross-Limb Stent-Graft Configuration on Hemodynamics in Abdominal Aortic Aneurysm Interventional Therapy
PurposeThe cross-limb (CL) technique is a commonly used endovascular treatment for addressing unfavorable anatomical features in patients with...
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Effect of Sinotubular Junction Size on TAVR Leaflet Thrombosis: A Fluid–Structure Interaction Analysis
TAVR has emerged as a standard approach for treating severe aortic stenosis patients. However, it is associated with several clinical complications,...
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Hemodynamic Control of Endothelial Cell Fates in Development
The vascular system initially forms as a random network of capillaries, which remodels under the influence of flow into efficient, hierarchical... -
DNA methylation signatures on vascular differentiation genes are aberrant in vessels of human cerebral arteriovenous malformation nidus
Arteriovenous malformation (AVM) is a tangle of arteries and veins, rupture of which can result in catastrophic hemorrhage in vulnerable sites such...
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Two Diverse Hemodynamic Forces, a Mechanical Stretch and a High Wall Shear Stress, Determine Intracranial Aneurysm Formation
Intracranial aneurysm (IA) usually induced at a bifurcation site of intracranial arteries causes a lethal subarachnoid hemorrhage. Currently, IA is...
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The Critical Biomechanics of Aortomitral Angle and Systolic Anterior Motion: Engineering Native Ex Vivo Simulation
Systolic anterior motion (SAM) of the mitral valve (MV) is a complex pathological phenomenon often occurring as an iatrogenic effect of surgical and...
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Assessing Early Cardiac Outflow Tract Adaptive Responses Through Combined Experimental-Computational Manipulations
Mechanical forces are essential for proper growth and remodeling of the primitive pharyngeal arch arteries (PAAs) into the great vessels of the...