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Pseudotyped Viruses for Influenza
We have developed an influenza hemagglutinin (HA) pseudotype (PV) library encompassing all influenza A (IAV) subtypes from HA1-HA18, influenza B...
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An Updated Review on Influenza Viruses
Influenza virus is a highly contagious respiratory virus also known as seasonal flu. This virus belongs to the Orthomyxoviridae family and its genome...
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Nucleotide sequence as key determinant driving insertions at influenza A virus hemagglutinin cleavage sites
Highly pathogenic avian influenza viruses (HPAIVs) emerge from H5 and H7 low pathogenic avian influenza viruses (LPAIVs), most frequently upon...
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H6N2 reassortant avian influenza virus isolate in wild birds in Jiangxi Province, China
H6 avian influenza virus is widely prevalent in wild birds and poultry and has caused human infection in 2013 in Taiwan, China. During our active...
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Genetic and virological characteristics of a reassortant avian influenza A H6N1 virus isolated from wild birds at a live-bird market in Egypt
The first detection of a human infection with avian influenza A/H6N1 virus in Taiwan in 2013 has raised concerns about this virus. During our routine...
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Antigenic comparison of the neuraminidases from recent influenza A vaccine viruses and 2019–2020 circulating strains
Although viral-based influenza vaccines contain neuraminidase (NA or N) antigens from the recommended seasonal strains, NA is not extensively...
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Estimation of Avian Influenza Viruses in Water Environments of Live Poultry Markets in Changsha, China, 2014 to 2018
In routine surveillance for avian influenza viruses (AIVs) in the environments of live poultry markets (LPMs), certain samples were positive for AIVs...
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Co-circulation of multiple reassortant H6 subtype avian influenza viruses in wild birds in eastern China, 2016–2017
BackgroundH6 subtype influenza viruses were prevalent in domestic poultry and wild birds, which also could pose potential threat to humans. However,...
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Genome sequence analysis of H7N3 subtype avian influenza virus originated from wild birds and its potential infectivity in mice
In 2021, an H7N3 avian influenza virus (AIV) was isolated from a mallard in Tianhewan Yellow River National Wetland Park, Ningxia Hui Autonomous...
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Development of an antigen-capture enzyme-linked immunosorbent assay and immunochromatographic strip based on monoclonal antibodies for detection of H6 avian influenza viruses
Continuous surveillance has shown that H6 subtype avian influenza viruses (AIVs) are prevalent in poultry and occasionally break the species barrier...
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Influenza Virus Entry inhibitors
Influenza is a major challenge to health and the global economy. However, the increasing emergence of drug resistance during influenza pandemics...
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Molecular epidemiology and genetic evolution of avian influenza H5N1 subtype in Nigeria, 2006 to 2021
Nigeria recorded one of the earliest outbreaks of the Highly Pathogenic Avian Influenza (HPAI) virus H5N1 in 2006, which spread to other African...
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Reverse transcription recombinase-aided amplification assay for avian influenza virus
Avian influenza virus (AIV) infection can lead to severe economic losses in the poultry industry and causes a serious risk for humans. A rapid and...
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Avian Influenza
Avian influenza (AI), informally known as “avian flu” or “bird flu,” causes devastating economic losses to poultry industries worldwide and is a...
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Highly pathogenic avian influenza A/Guangdong/17SF003/2016 is immunogenic and induces cross-protection against antigenically divergent H7N9 viruses
Avian influenza A(H7N9) epidemics have a fatality rate of approximately 40%. Previous studies reported that low pathogenic avian influenza...
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Safety and immunogenicity of a ferritin nanoparticle H2 influenza vaccine in healthy adults: a phase 1 trial
Currently, licensed seasonal influenza vaccines display variable vaccine effectiveness, and there remains a need for novel vaccine platforms capable...
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A chimeric thermostable M2e and H3 stalk-based universal influenza A virus vaccine
We developed a new chimeric M2e and H3 hemagglutinin (HA) stalk protein vaccine (M2e-H3 stalk) by genetic engineering of modified H3 stalk domain...
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Baseline innate and T cell populations are correlates of protection against symptomatic influenza virus infection independent of serology
Evidence suggests that innate and adaptive cellular responses mediate resistance to the influenza virus and confer protection after vaccination....
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Characterization of H3 subtype avian influenza viruses isolated from poultry in Vietnam
To date, avian influenza viruses (AIVs) have persisted in domestic poultry in wet markets in East Asian countries. We have performed ongoing virus...
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Increased virulence of a novel reassortant H1N3 avian influenza virus in mice as a result of adaptive amino acid substitutions
In this study, a novel multiple-gene reassortant H1N3 subtype avian influenza virus (AIV) (A/chicken/Zhejiang/81213/2017, CK81213) was isolated in...
