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Scoring for Hemorrhage Severity in Traumatic Injury
Severity scores have long been used for the classification or stratification of patients for clinical care and in the evaluation of outcomes. Such... -
Cerebellar Volumetry in Ataxias: Relation to Ataxia Severity and Duration
Cerebellar atrophy is the neuropathological hallmark of most ataxias. Hence, quantifying the volume of the cerebellar grey and white matter is of...
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Predicting the Disease Severity of Virus Infection
The COVID-19 pandemic has resulted in unprecedented burden on global health and economic systems, promoting worldwide efforts to understand, control,... -
Scoring for Hemorrhage Severity in Traumatic Injury
Severity scores have long been used for the classification or stratification of patients for clinical care and in the evaluation of outcomes. Such... -
Human Genetics of d-Transposition of Great Arteries
Although several genes underlying occurrence of transposition of the great arteries have been found in the mouse, human genetics of the most frequent... -
Association of women-specific health factors in the severity of Parkinson’s disease
Parkinson’s disease (PD) is an age-related neurological disorder known for the observational differences in its risk, progression, and severity...
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Gender-related Characteristics of Oxidative Stress Severity and Cognitive Impairment in Patients With Schizophrenia
The gender specificity of the clinical and psychopathological features of schizophrenia is an important factor in this disease. Gender features of...
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Spinal cord injury etiology, severity, and care in East Asia: a cross-sectional analysis of the International Spinal Cord Society Database Project
Study designCross-sectional study.
ObjectivesTo evaluate etiologic factors associated with spinal cord injury (SCI) severity and to identify...
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Monitoring of optic sheath diameter during acute migraine attack: an objective criteria for the severity of disease
BackgroundThe etiology of migraine can be complex and multifactorial but not clear, also, intracranial pressure has been already associated with...
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Plasma Torquetenovirus (TTV) microRNAs and severity of COVID-19
BackgroundTorquetenovirus (TTV), a widespread anellovirus recognized as the main component of the healthy human virome, displays viremia that is...
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Bruton’s tyrosine kinase inhibition reduces disease severity in a model of secondary progressive autoimmune demyelination
Bruton’s tyrosine kinase (BTK) is an emerging target in multiple sclerosis (MS). Alongside its role in B cell receptor signaling and B cell...
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Human Genetic Variants Associated with COVID-19 Severity are Enriched in Immune and Epithelium Regulatory Networks
Human genetic variants can influence the severity of symptoms infected with SARS-COV-2. Several genome-wide association studies have identified human...
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On the relationship between tripartite motif-containing 22 single-nucleotide polymorphisms and COVID-19 infection severity
BackgroundThe tripartite motif containing ( TRIM )-22 participates in innate immune responses and exhibits antiviral activities. The present study...
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Involvement of IL-17 A/IL-17 Receptor A with Neutrophil Recruitment and the Severity of Coronary Arteritis in Kawasaki Disease
PurposeTo assess the role of the interleukin (IL)-17 A/IL-17 receptor A (IL-17RA) in Kawasaki disease (KD)-related coronary arteritis (CA).
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Energy Status of Lymphocytes in Children with Bronchial Asthma of Various Severity in Comparison with Frequently Ill and Healthy Children
We studied disturbances of cellular energy exchange as one of the leading factors in the development of chronic inflammation in asthma. Comparison of...
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A SACS deletion variant in Great Pyrenees dogs causes autosomal recessive neuronal degeneration
ARSACS (autosomal recessive spastic ataxia of Charlevoix-Saguenay) is a human neurological disorder characterized by progressive cerebellar ataxia...
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NAIP Gene Deletion and SMN2 Copy Number as Molecular Tools in Predicting the Severity of Spinal Muscular Atrophy
Spinal muscular atrophy (SMA) is one of the most prevalent autosomal recessive illnesses with type I being the most severe type. Genomic alterations...
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Whole mitogenome sequencing uncovers a relation between mitochondrial heteroplasmy and leprosy severity
BackgroundIn recent years, the mitochondria/immune system interaction has been proposed, so that variants of mitochondrial genome and levels of...
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The quantity and quality of anti-SARS-CoV-2 antibodies show contrariwise association with COVID-19 severity: lessons learned from IgG avidity
Gaining more appreciation on the protective/damaging aspects of anti-SARS-CoV-2 immunity associated with disease severity is of great importance....
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Does severity of spinal cord injury predict likelihood of suffering chronically from severe depression and anxiety?
Study designQualitative Survey study.
ObjectiveOne might assume that those with higher and more complete spinal cord injuries are at higher risk of...