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  1. Scoring for Hemorrhage Severity in Traumatic Injury

    Severity scores have long been used for the classification or stratification of patients for clinical care and in the evaluation of outcomes. Such...
    Benjamin Shickel, Jeremy Balch, ... Anthony Guiseppi-Elie in Biomarkers in Trauma, Injury and Critical Care
    Reference work entry 2023
  2. Cerebellar Volumetry in Ataxias: Relation to Ataxia Severity and Duration

    Cerebellar atrophy is the neuropathological hallmark of most ataxias. Hence, quantifying the volume of the cerebellar grey and white matter is of...

    Mónica Ferreira, Tamara Schaprian, ... Jennifer Faber in The Cerebellum
    Article Open access 16 February 2024
  3. Predicting the Disease Severity of Virus Infection

    The COVID-19 pandemic has resulted in unprecedented burden on global health and economic systems, promoting worldwide efforts to understand, control,...
    **n Qi, Li Shen, ... Bairong Shen in Translational Informatics
    Chapter 2022
  4. Scoring for Hemorrhage Severity in Traumatic Injury

    Severity scores have long been used for the classification or stratification of patients for clinical care and in the evaluation of outcomes. Such...
    Benjamin Shickel, Jeremy Balch, ... Anthony Guiseppi-Elie in Biomarkers in Trauma, Injury and Critical Care
    Living reference work entry 2022
  5. Human Genetics of d-Transposition of Great Arteries

    Although several genes underlying occurrence of transposition of the great arteries have been found in the mouse, human genetics of the most frequent...
    Chapter 2024
  6. Association of women-specific health factors in the severity of Parkinson’s disease

    Parkinson’s disease (PD) is an age-related neurological disorder known for the observational differences in its risk, progression, and severity...

    Shilpa C. Rao, Yadi Li, ... Ignacio F. Mata in npj Parkinson's Disease
    Article Open access 05 June 2023
  7. Gender-related Characteristics of Oxidative Stress Severity and Cognitive Impairment in Patients With Schizophrenia

    The gender specificity of the clinical and psychopathological features of schizophrenia is an important factor in this disease. Gender features of...

    Anna Sergeevna Piatoikina, Tatiana Vladimirovna Zhilyaeva, ... Galina Elevna Mazo in Journal of Molecular Neuroscience
    Article 05 August 2023
  8. Spinal cord injury etiology, severity, and care in East Asia: a cross-sectional analysis of the International Spinal Cord Society Database Project

    Study design

    Cross-sectional study.

    Objectives

    To evaluate etiologic factors associated with spinal cord injury (SCI) severity and to identify...

    Benjamin D. Holmes, Ruta Brazauskas, Harvinder S. Chhabra in Spinal Cord
    Article 24 June 2024
  9. Monitoring of optic sheath diameter during acute migraine attack: an objective criteria for the severity of disease

    Background

    The etiology of migraine can be complex and multifactorial but not clear, also, intracranial pressure has been already associated with...

    Sadullah Şimşek, Edip Gültekin, Akif İşlek in Acta Neurologica Belgica
    Article 09 January 2024
  10. Plasma Torquetenovirus (TTV) microRNAs and severity of COVID-19

    Background

    Torquetenovirus (TTV), a widespread anellovirus recognized as the main component of the healthy human virome, displays viremia that is...

    Maria Alfreda Stincarelli, Andreina Baj, ... Simone Giannecchini in Virology Journal
    Article Open access 13 May 2022
  11. Bruton’s tyrosine kinase inhibition reduces disease severity in a model of secondary progressive autoimmune demyelination

    Bruton’s tyrosine kinase (BTK) is an emerging target in multiple sclerosis (MS). Alongside its role in B cell receptor signaling and B cell...

    Kirsten Scarlett Evonuk, Sen Wang, ... Suzana Marušić in Acta Neuropathologica Communications
    Article Open access 12 July 2023
  12. Human Genetic Variants Associated with COVID-19 Severity are Enriched in Immune and Epithelium Regulatory Networks

    Human genetic variants can influence the severity of symptoms infected with SARS-COV-2. Several genome-wide association studies have identified human...

    Zhanying Feng, **anwen Ren, ... Yong Wang in Phenomics
    Article 13 August 2022
  13. On the relationship between tripartite motif-containing 22 single-nucleotide polymorphisms and COVID-19 infection severity

    Background

    The tripartite motif containing ( TRIM )-22 participates in innate immune responses and exhibits antiviral activities. The present study...

    Nidhal Raheem Juhi Al-Kaabi, Sepideh Chodari Khameneh, ... Abolfazl Fateh in Human Genomics
    Article Open access 26 August 2022
  14. Involvement of IL-17 A/IL-17 Receptor A with Neutrophil Recruitment and the Severity of Coronary Arteritis in Kawasaki Disease

    Purpose

    To assess the role of the interleukin (IL)-17 A/IL-17 receptor A (IL-17RA) in Kawasaki disease (KD)-related coronary arteritis (CA).

    ...
    I-Chun Lin, Jau-Ling Suen, ... Lin Wang in Journal of Clinical Immunology
    Article Open access 07 March 2024
  15. Energy Status of Lymphocytes in Children with Bronchial Asthma of Various Severity in Comparison with Frequently Ill and Healthy Children

    We studied disturbances of cellular energy exchange as one of the leading factors in the development of chronic inflammation in asthma. Comparison of...

    M. V. Akulenko, N. I. Kosyakova in Bulletin of Experimental Biology and Medicine
    Article 01 October 2022
  16. A SACS deletion variant in Great Pyrenees dogs causes autosomal recessive neuronal degeneration

    ARSACS (autosomal recessive spastic ataxia of Charlevoix-Saguenay) is a human neurological disorder characterized by progressive cerebellar ataxia...

    Kari J. Ekenstedt, Katie M. Minor, ... James R. Mickelson in Human Genetics
    Article Open access 27 September 2023
  17. NAIP Gene Deletion and SMN2 Copy Number as Molecular Tools in Predicting the Severity of Spinal Muscular Atrophy

    Spinal muscular atrophy (SMA) is one of the most prevalent autosomal recessive illnesses with type I being the most severe type. Genomic alterations...

    Abdel Nasser H. Abd El Mutaleb, Fawziya A. R. Ibrahim, ... Mona M. Rashad in Biochemical Genetics
    Article Open access 22 February 2024
  18. Whole mitogenome sequencing uncovers a relation between mitochondrial heteroplasmy and leprosy severity

    Background

    In recent years, the mitochondria/immune system interaction has been proposed, so that variants of mitochondrial genome and levels of...

    Felipe Gouvea de Souza, Moisés Batista da Silva, ... Giovanna C. Cavalcante in Human Genomics
    Article Open access 08 December 2023
  19. The quantity and quality of anti-SARS-CoV-2 antibodies show contrariwise association with COVID-19 severity: lessons learned from IgG avidity

    Gaining more appreciation on the protective/damaging aspects of anti-SARS-CoV-2 immunity associated with disease severity is of great importance....

    Mehrdad Hajilooi, Fariba Keramat, ... Ghasem Solgi in Medical Microbiology and Immunology
    Article 27 April 2023
  20. Does severity of spinal cord injury predict likelihood of suffering chronically from severe depression and anxiety?

    Study design

    Qualitative Survey study.

    Objective

    One might assume that those with higher and more complete spinal cord injuries are at higher risk of...

    Avni Khandelwal, Leigh Anne Shafer, Karen Ethans in Spinal Cord Series and Cases
    Article 01 June 2022
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