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Food Seeking in Spite of Harmful Consequences
In industrialized nations, overeating is a significant problem leading to overweight, obesity, and a host of related disorders; the increase in these...
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Situating Habit and Goal-Direction in a General View of Instrumental Behavior
This chapter reviews recent research from the author’s laboratory on habit and goal-direction in instrumental learning and then considers some of its...
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Sex differences and sex-specific regulation of motivated behavior by Melanin-concentrating hormone: a short review
Recent preclinical research exploring how neuropeptide transmitter systems regulate motivated behavior reveal the increasing importance of sex as a...
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Clozapine N-oxide, compound 21, and JHU37160 do not influence effortful reward-seeking behavior in mice
RationaleClozapine N-oxide (CNO) has been developed as a ligand to selectively activate designer receptors exclusively activated by designer drugs...
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Next-generation neuropeptide Y receptor small-molecule agonists inhibit mosquito-biting behavior
BackgroundFemale Aedes aegypti mosquitoes can spread disease-causing pathogens when they bite humans to obtain blood nutrients required for egg...
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The effects of hydrocortisone and yohimbine on human behavior in approach-avoidance conflicts
RationaleBalancing approach of positive and avoidance of negative stimuli is essential when faced with approach-avoidance conflicts, e.g., situations...
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Pavlovian Spontaneous Recovery as a Measure of Alcohol-Seeking Behavior
Alcohol (EtOH) addiction can be characterized as a chronic relapsing disorder. EtOH craving is a critical precipitating factor to relapse....
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Nicotinic and muscarinic acetylcholine receptor antagonism dose-dependently decreases sign- but not goal-tracking behavior in male rats
RationaleAcetylcholinergic antagonists have shown some promise in reducing addiction-related behaviors in both preclinical and clinical studies....
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Operant social self-administration in male CD1 mice
Rationale and ObjectiveWe recently introduced a model of operant social reward in which female CD1 mice lever press for access to affiliative social...
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Parental Behavior
Maternal behavior (MB) in mammals is a goal-directed behavior adapted for ensuring the survival of a female’s offspring. It includes a constellation...
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Long-term effects of THC exposure on reward learning and motivated behavior in adolescent and adult male rats
RationaleThe endocannabinoid system makes critical contributions to reward processing, motivation, and behavioral control. Repeated exposure to THC...
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Melanin-concentrating hormone and orexin shape social affective behavior via action in the insular cortex of rat
RationaleIn a social context, individuals are able to detect external information from others and coordinate behavioral responses according to the...
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A role for leptin and ghrelin in the augmentation of heroin seeking induced by chronic food restriction
RationalCaloric restriction increases the risk of relapse in abstinent drug users. Hormones involved in the regulation of energy balance and food...
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Corticosterone after early adolescent stress prevents social avoidance, aversive behavior, and morphine-conditioned place preference in adulthood
RationaleStress during childhood or adolescence increases vulnerability to psychiatric disorders in adults. In adult rodents, the delayed effects of...
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Neuroendocrine Control of Maternal Behavior
Maternal caregiving is an essential component of successful mammalian reproduction. Indeed, almost all mothers exhibit a species-typical repertoire...
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Effect of Aquaculture Sound on Fish Development, Physiology, and Behavior
This chapter reviews studies on the effect of aquaculture sounds from pumps, generators, and other equipment on the development, physiology, and...
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Hormone Effects on Behavior
Hormone effects on brain and behavior surprisingly turned out to be (i) the first convincing demonstration of body-to-brain signaling and (ii) the...
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A head-to-head comparison of two DREADD agonists for suppressing operant behavior in rats via VTA dopamine neuron inhibition
RationaleDesigner receptors exclusively activated by designer drugs (DREADDs) are a tool for “remote control” of defined neuronal populations during...
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Evaluating the potential impact of lifestyle-based behavior change interventions delivered at the time of colorectal cancer screening
PurposeTo analyze interventions implemented at the time of colorectal cancer (CRC) screening, or among individuals who have previously undergone...
