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Accurate object localization facilitates automatic esophagus segmentation in deep learning
BackgroundCurrently, automatic esophagus segmentation remains a challenging task due to its small size, low contrast, and large shape variation. We...
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Potential drug targets for gastroesophageal reflux disease and Barrett’s esophagus identified through Mendelian randomization analysis
Gastroesophageal reflux disease (GERD) is a prevalent chronic ailment, and present therapeutic approaches are not always effective. This study aimed...
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Localization of substance P (SP)-immunoreactivity in the myenteric plexus of the rat esophagus
The present immunohistochemical study was performed to examine the number, distribution, and chemical coding of intrinsic substance P (SP) neurons...
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The causal associations of circulating lipids with Barrett’s Esophagus and Esophageal Cancer: a bi-directional, two sample mendelian randomization analysis
ObjectiveThe causal associations of circulating lipids with Barrett’s Esophagus (BE) and Esophageal Cancer (EC) has been a topic of debate. This...
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Dutch, UK and US professionals’ perceptions of screening for Barrett’s esophagus and esophageal adenocarcinoma: a concept map** study
BackgroundNovel, less-invasive technologies to screen for Barrett’s esophagus (BE) may enable a paradigm shift in early detection strategies for...
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PARG Promotes Esophagus Cancer Cell Metastasis by Activation of the Wnt/β-Catenin Pathway
Esophagus cancer (EC) is a highly malignant and metastatic cancer. Poly(ADP-ribose) glycohydrolase (PARG), a DNA replication and repair regulator,...
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Esophagus Decellularization
In pathologies of the esophagus such as esophageal atresia, cancers and caustic injuries, methods for full thickness esophageal replacement require...
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Prevalence and risk factors of barrett’s esophagus in lynch syndrome
Lynch syndrome (LS), the most common hereditary cause of colorectal cancer, predisposes to upper gastrointestinal neoplasia. The prevalence of...
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Multicenter analysis on the value of standard (chemo)radiotherapy in elderly patients with locally advanced adenocarcinoma of the esophagus or gastroesophageal junction
BackgroundTo assess the tolerability and oncological results of chemoradiation in elderly patients with locally advanced adenocarcinoma of the...
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Targeted genetic and epigenetic profiling of esophageal adenocarcinomas and non-dysplastic Barrett’s esophagus
BackgroundDespite the efforts to describe the molecular landscape of esophageal adenocarcinoma (EAC) and its precursor lesion Barrett’s esophagus...
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Pre-operative anemia and peri-operative transfusion are associated with poor oncologic outcomes in cancers of the esophagus: potential impact of patient blood management on cancer outcomes
BackgroundBoth Red Blood Cell (RBC) transfusion and anemia are thought to negatively impact cancer survival. These effects have been reported with...
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Triage-driven diagnosis of Barrett’s esophagus for early detection of esophageal adenocarcinoma using deep learning
Deep learning methods have been shown to achieve excellent performance on diagnostic tasks, but how to optimally combine them with expert knowledge...
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Multi-omics of the esophageal microenvironment identifies signatures associated with progression of Barrett’s esophagus
BackgroundThe enrichment of Gram-negative bacteria of oral origin in the esophageal microbiome has been associated with the development of...
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Postprandial proximal gastric acid pocket and its association with gastroesophageal acid reflux in patients with short-segment Barrett’s esophagus
ObjectiveTo determine the characteristics of postprandial proximal gastric acid pockets (PPGAPs) and their association with gastroesophageal acid...
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Botulinum Toxin Therapy for Problems Related to the Gastrointestinal System (Alimentary Tract)
Injection of Botulinum toxins into the sphincters of the alimentary tract improves symptoms due to contraction and spasm of these circular muscles...
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Purinergic inhibitory regulation of esophageal smooth muscle is mediated by P2Y receptors and ATP-dependent potassium channels in rats
Purines such as ATP are regulatory transmitters in motility of the gastrointestinal tract. The aims of this study were to propose functional roles of...
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Development of Novel Balloon-Integrated Optical Catheter for Endoscopic and Circumferential Laser Application
The current study aims to demonstrate the feasibility of a novel balloon-integrated optical catheter (BIOC) to achieve endoscopic laser application...
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Notch1 mutations drive clonal expansion in normal esophageal epithelium but impair tumor growth
NOTCH1 mutant clones occupy the majority of normal human esophagus by middle age but are comparatively rare in esophageal cancers, suggesting NOTCH1 ...
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Histological differentiation of mucus cell subtypes suggests functional compartmentation in the eel esophagus
We investigated the morphological and histological changes in eel esophagus during the course of freshwater (FW) to seawater (SW) transfer and...
