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Electroretinogram (ERG) to Evaluate the Retina in Cases of Retinitis Pigmentosa (RP)
Electroretinogram (ERG) captures the electrical responses of photoreceptors, the summation of action potentials from all neurons in the retina... -
Electroretinogram (ERG) to Evaluate the Retina Using Mouse Models
Electroretinogram (ERG) is a sensitive and useful tool for the measurement of the retinaRetinas’s electrical response to flash stimuli. It provides a... -
Assessing Rewiring of the Retinal Circuitry by Electroretinogram (ERG) After Inner Retinal Lesion in Adult Zebrafish
Adult zebrafish respond to retinal injury with a regenerative response that replaces damaged neurons with Müller glia-derived regenerated neurons.... -
Measuring the Full-Field Electroretinogram in Rodents
Electroretinography allows for noninvasive functional assessment of the retina and is a mainstay for preclinical studies of retinal function in... -
Group comparisons of the individual electroretinogram time trajectories for the ascending limb of the b-wave using a raw and registered time series
ObjectivesThe electroretinogram is a clinical test commonly used in the diagnosis of retinal disorders with the peak time and amplitude of the a- and...
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The electroretinogram b-wave amplitude: a differential physiological measure for Attention Deficit Hyperactivity Disorder and Autism Spectrum Disorder
BackgroundAttention Deficit Hyperactivity Disorder (ADHD) is the most prevalent childhood neurodevelopmental disorder. It shares some genetic risk...
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Fractal Phototherapy in Maximizing Retina and Brain Plasticity
The neuroplasticity potential is reduced with aging and impairs during neurodegenerative diseases and brain and visual system injuries. This limits... -
Intravitreal Delivery of PEGylated-ECO Plasmid DNA Nanoparticles for Gene Therapy of Stargardt Disease
ObjectiveCurrent gene therapy of inherited retinal diseases is achieved mainly by subretinal injection, which is invasive with severe adverse...
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Electroretinographic Studies of the Crew of the Eight-Month International Experiment SIRIUS 20/21
A set of electrophysiological studies of the visual system was run before and after the eight-month SIRIUS 20/21 international experiment, with...
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High-Throughput Binocular Pattern Electroretinograms in the Mouse
The pattern electroretinogram (PERG) reflects the electrical activity of retinal ganglion cells (RGC) and has become the most used technology to... -
CREG Protects Retinal Ganglion Cells loss and Retinal Function Impairment Against ischemia-reperfusion Injury in mice via Akt Signaling Pathway
PurposeThe irreversible death of retinal ganglion cells (RGCs) plays an important role in the pathogenesis of glaucoma. Cellular repressor of...
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Akimba Proliferative Diabetic Retinopathy Model: Understanding Molecular Mechanism and Drug Screening for the Progression of Diabetic Retinopathy
As the prevalence of diabetes has reached epidemic proportions worldwide, diabetic retinopathy incidence is increasing rapidly. An advanced diabetic... -
Granzyme B degrades extracellular matrix and promotes inflammation and choroidal neovascularization
Age-related macular degeneration (AMD) is a common retinal neurodegenerative disease among the elderly. Neovascular AMD (nAMD), a leading cause of...
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Microglia preserve visual function in the aging retina by supporting retinal pigment epithelial health
BackgroundIncreased age is a risk factor for the development and progression of retinal diseases including age-related macular degeneration (AMD)....
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Psychophysiology and Electrophysiology of the Visual System
The organization of the human afferent visual system is complex and visual processing requires enormous computational challenges and energy... -
Comparison of retinal degeneration treatment with four types of different mesenchymal stem cells, human induced pluripotent stem cells and RPE cells in a rat retinal degeneration model
BackgroundRetinal degeneration (RD) is a group of disorders on irreversible vision loss. Multiple types of stem cells were used in clinical trials...
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Blue light exposure collapses the inner blood-retinal barrier by accelerating endothelial CLDN5 degradation through the disturbance of GNAZ and the activation of ADAM17
Blue light is part of the natural light spectrum that emits high energy. Currently, people are frequently exposed to blue light from 3C devices,...
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Scrutinizing pathogenicity of the USH2A c.2276 G > T; p.(Cys759Phe) variant
The USH2A variant c.2276 G > T (p.(Cys759Phe)) has been described by many authors as a frequent cause of autosomal recessive retinitis pigmentosa...
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Retinal Assessment Using In Vivo Electroretinography and Optical Coherence Tomography in Rodent Models of Diabetes
Electroretinography and optical coherence tomography imaging allow for non-invasive quantitative assessment of the retina. These approaches have... -
Large Animal Models of Retinitis Pigmentosa in Therapy Development and Preclinical Testing
Large animal models are valuable for develo** and testing translational therapies for inherited retinal dystrophies such as retinitis pigmentosa...