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The role of the soft palate dose regarding normal tissue toxicities in older adults with head and neck cancer undergoing definitive radiotherapy
PurposeThe number of older adults with head and neck squamous cell carcinoma (HNSCC) is continuously increasing. Older HNSCC patients may be more...
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Dose-response relationship between volume base dose and tumor local control in definitive radiotherapy for vaginal cancer
ObjectiveThis study aimed to establish the dose-response relationship between volume base dose and tumor local control for vaginal cancer, including...
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Prognostic value of baseline 18F-FDG PET/CT in patients with esophageal squamous cell carcinoma treated with definitive (chemo)radiotherapy
PurposeTo investigate the prognostic value of baseline 18 F-FDG PET/CT in patients with esophageal squamous cell carcinoma (ESCC) treated with...
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Radiotherapy for Meningioma
Meningiomas are the most common primary intracranial brain tumor, and have a heterogeneous biology and an unmet need for targeted treatment options.... -
Whether individualized dose escalation should be recommended for lymph nodes with different sizes in the definitive radiotherapy of cervical cancer?
Background and purposeDose escalation for positive node maybe improve the regional control of patients with node-positive cervical cancer, but the...
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Prognostic value of tumor-infiltrating immune cells and immune checkpoints in elderly head-and-neck squamous cell carcinoma patients undergoing definitive (chemo)radiotherapy
Background and purposeTumor-infiltrating lymphocytes (TILs) are associated with locoregional control (LRC) in head-and-neck squamous cell carcinoma...
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PET-CT detection of local residual laryngeal carcinoma after definitive (chemo)radiotherapy
BackgroundPositron emission tomography and computed tomography (PET-CT) is currently recommended in evaluating the treatment response after...
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Clinical features and risk factors for interstitial lung disease spreading in low-dose irradiated areas after definitive radiotherapy with or without durvalumab consolidation therapy for patients with non-small cell lung cancer
BackgroundThe current standard of care for patients with unresectable locally advanced non-small cell lung cancer (NSCLC) is chemoradiotherapy (CRT)...
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Prognostic value of pre-therapeutic nutritional risk factors in elderly patients with locally advanced esophageal squamous cell carcinoma receiving definitive chemoradiotherapy or radiotherapy
BackgroundThe nutritional status of cancer patients is a crucial factor in determining their prognosis. The objective of this study was to...
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Concurrent definitive chemoradiation incorporating intensity-modulated radiotherapy followed by adjuvant chemotherapy in high risk locally advanced cervical squamous cancer: a phase II study
BackgroundAlthough the prognosis of locally advanced cervical cancer has improved dramatically, survival for those with stage IIIB-IVA disease or...
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Multicenter analysis on the value of standard (chemo)radiotherapy in elderly patients with locally advanced adenocarcinoma of the esophagus or gastroesophageal junction
BackgroundTo assess the tolerability and oncological results of chemoradiation in elderly patients with locally advanced adenocarcinoma of the...
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Androgen deprivation therapy and acute kidney injury in patients with prostate cancer undergoing definitive radiotherapy
BackgroundAndrogen deprivation therapy (ADT) is frequently utilized in conjunction with radiotherapy (RT) in the definitive management of prostate...
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Biochemical recurrence in patients with prostate cancer after primary definitive therapy: treatment based on risk stratification
BackgroundNearly one-third of patients with prostate cancer (PCa) experience biochemical recurrence (BCR) after primary definitive treatment. BCR...
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Definitive carbon ion radiotherapy for tracheobronchial adenoid cystic carcinoma: a preliminary report
BackgroundTracheobronchial adenoid cystic carcinoma (TACC) is a rare tumour. About one-third of patients miss their chance of surgery or complete...
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Radiation Therapy in the Definitive Treatment of Cancer
Radiation therapy is an important component of cancer treatment for a variety of malignancies both in the definitive and palliative setting.... -
PErspective and current status of Radiotherapy Service in IRan (PERSIR)-1 study: assessment of current external beam radiotherapy facilities, staff and techniques compared to the international guidelines
Background and purposeRadiotherapy (RT) is an essential treatment modality against cancer and becoming even more in demand due to the anticipated...
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Protocol of a phase II study to evaluate the efficacy and safety of deep-inspiration breath-hold daily online adaptive radiotherapy for centrally located lung tumours (PUDDING study)
BackgroundCentrally located lung tumours present a challenge because of their tendency to exhibit symptoms such as airway obstruction, atelectasis,...
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A randomized phase II trial of MR-guided prostate stereotactic body radiotherapy administered in 5 or 2 fractions for localized prostate cancer (FORT)
BackgroundUltra-hypofractionated regimens for definitive prostate cancer (PCa) radiotherapy are increasingly utilized due in part to promising safety...
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Validation of an MRI-only planning workflow for definitive pelvic radiotherapy
PurposePrevious work on Magnetic Resonance Imaging (MRI) only planning has been applied to limited treatment regions with a focus on male anatomy....
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A nationwide study of breast reconstruction after mastectomy in patients with breast cancer receiving postmastectomy radiotherapy: comparison of complications according to radiotherapy fractionation and reconstruction procedures
BackgroundWe examined the patterns of breast reconstruction postmastectomy in breast cancer patients undergoing postmastectomy radiotherapy (PMRT)...