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Biomarkers of moderate alcohol intake and alcoholic beverages: a systematic literature review
The predominant source of alcohol in the diet is alcoholic beverages, including beer, wine, spirits and liquors, sweet wine, and ciders....
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Short-chain fatty acid valerate reduces voluntary alcohol intake in male mice
BackgroundDespite serious health and social consequences, effective intervention strategies for habitual alcohol binge drinking are lacking. The...
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Effect of the glucagon-like peptide-1 (GLP-1) receptor agonist semaglutide on alcohol consumption in alcohol-preferring male vervet monkeys
RationaleGlucagon-like peptide-1 (GLP-1) receptor agonists reduce alcohol consumption in rodents and non-human primates. Semaglutide is a new...
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The Association of Iron Intake and Hypertension, Does Iron Intake Decrease Blood Pressure?
Previous studies reported that iron may have an indispensable role in the risk of hypertension (HTN). However, the result of the studies on the...
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Sex differences in stress-induced alcohol intake: a review of preclinical studies focused on amygdala and inflammatory pathways
Clinical studies suggest that women are more likely than men to relapse to alcohol drinking in response to stress; however, the mechanisms underlying...
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Alcohol: Neurobiology of Alcohol Addiction
Consumption of alcohol is the third leading cause of preventable deaths worldwide making it a major public health issue. After a brief account of the... -
Adolescent alcohol binge drinking and withdrawal: behavioural, brain GFAP-positive astrocytes and acute methamphetamine effects in adult female rats
RationaleAlcopop beverages are generally the first alcoholic beverage that young females drink which contain high levels of sugar and alcohol. The...
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Alcohol consumption and risks of more than 200 diseases in Chinese men
Alcohol consumption accounts for ~3 million annual deaths worldwide, but uncertainty persists about its relationships with many diseases. We...
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Subthalamic high-frequency deep brain stimulation reduces addiction-like alcohol use and the possible negative influence of a peer presence
RationaleThe immediate social context significantly influences alcohol consumption in humans. Recent studies have revealed that peer presence could...
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Animal Models of Binge Eating: Hedonic Feeding and Alcohol Intake
Binge eating is a behavioral component of some eating disorders associated with the development of obesity and associated metabolic pathologies. Over... -
Liraglutide Reduces Alcohol Consumption, Anxiety, Memory Impairment, and Synapse Loss in Alcohol Dependent Mice
Glucagon-like peptide 1 (GLP-1) analogues have been commercialized for the management of type 2 diabetes. Recent studies have underscored GLP-1’s...
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The potential effects of HECTD4 variants on fasting glucose and triglyceride levels in relation to prevalence of type 2 diabetes based on alcohol intake
Excessive alcohol intake is an important cause of major public health problem in East Asian countries. Growing evidence suggests that genetic factors...
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Psilocybin prevents reinstatement of alcohol seeking by disrupting the reconsolidation of alcohol-related memories
BackgroundFor most psychiatric conditions, including alcohol use disorder (AUD), FDA-approved pharmacological treatments are limited and their...
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Predicting daily recovery during long-term endurance training using machine learning analysis
PurposeThe aim of this study was to determine if machine learning models could predict the perceived morning recovery status (AM PRS) and daily...
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Prospective cohort of pre- and post-diagnosis alcohol consumption and cigarette smoking on survival outcomes: an Alberta Endometrial Cancer Cohort Study
PurposeTo examine the independent and joint relationships between cigarette smoking and alcohol consumption with survival outcomes after endometrial...
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Ethanol Intake on Preclinical Models: Methods of Assessment and Effects on Dopamine Signaling
Alcohol (ethanol) use is associated with significant health problems. This prompted efforts to recreate ethanol intake in murine animal models. The... -
Pregnenolone effects on provoked alcohol craving, anxiety, HPA axis, and autonomic arousal in individuals with alcohol use disorder
RationaleChronic alcohol intake down-regulates GABAergic transmission and reduces levels of neuroactive steroids. These changes are associated with...
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Different mechanisms underlie compulsive alcohol self-administration in male and female rats
BackgroundSex is an important factor in the progression and treatment of alcohol addiction, and therapeutic approaches may have to be tailored to...
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The effect of concurrent access to alcohol and oxycodone on self-administration and reinstatement in rats
RationaleAlthough polysubstance use is highly prevalent, preclinical studies that assess voluntary consumption of multiple substances at the same...