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Screening and Clinical Verification of Extracellular Vesicle Biomarkers
Extracellular vesicles (EVs), lipid bilayer-encapsulated membrane particles carrying proteins, lipids, nucleic acids, and sugars, are shed by most...
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Clinical application of a GPU-accelerated monte carlo dose verification for cyberknife M6 with Iris collimator
PurposeTo apply an independent GPU-accelerated Monte Carlo (MC) dose verification for CyberKnife M6 with Iris collimator and evaluate the dose...
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A verification phase adds little value to the determination of maximum oxygen uptake in well-trained adults
PurposeThe objective was to investigate if performing a sub-peak or supra-peak verification phase following a ramp test provides additional value for...
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Characterization and clinical verification of immune-related genes in hepatocellular carcinoma to aid prognosis evaluation and immunotherapy
BackgroundImmune-related genes (IRGs) have been confirmed to play an important role in tumorigenesis and tumor microenvironment formation in...
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Study of PRESAGE® dosimeter for end-to-end 3D radiotherapy verification using an anthropomorphic phantom with bespoke dosimeter insert
Modern radiotherapy techniques have advanced and become more sophisticated. End-to-end 3D verification of the complex radiotherapy dose distribution...
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Development and verification of a nomogram for predicting the prognosis of resectable gastric cancer with outlet obstruction
BackgroundThe prognosis of patients with gastric cancer (GC) with gastric outlet obstruction (GOO) after gastrectomy is highly variable. In this...
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Verification of prognostic expression biomarkers is improved by examining enriched leukemic blasts rather than mononuclear cells from acute myeloid leukemia patients
BackgroundStudies have not systematically compared the ability to verify performance of prognostic transcripts in paired bulk mononuclear cells...
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Shortening image registration time using a deep neural network for patient positional verification in radiotherapy
We sought to accelerate 2D/3D image registration computation time using image synthesis with a deep neural network (DNN) to generate digitally...
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Clinical Neuroembryology Development and Developmental Disorders of the Human Central Nervous System
This book provides a comprehensive overview of the development of the human central nervous system (CNS) in the context of its many developmental...
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Sha** Clinical Reasoning
Clinical reasoningReasoning, clinical is at the core of all healthHealth-related professions, and it is long recognized as a critical skillSkill for...
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Uncovering the Mechanism of Chinese Hawthorn Leaf on Myocardial Ischemia Based on Network Pharmacology, Molecular Docking Verification, and In Vitro Studies
Hawthorn leaf has shown therapeutic effects in the patients with myocardial ischemia. Our study combines network pharmacology, molecular docking...
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A novel rat model for cerebral venous sinus thrombosis: verification of similarity to human disease via clinical analysis and experimental validation
BackgroundCerebral venous sinus thrombosis (CVST) is a rare neurovascular disorder with highly variable manifestations and clinical courses. Animal...
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Prostate volume analysis in image registration for prostate cancer care: a verification study
Combined magnetic resonance imaging (MRI) and positron emission tomography/computed tomography (PET/CT) may enhance diagnosis, aid surgical planning...
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Validation and Verification of High-Fidelity Simulations of Thoracic Stent-Graft Implantation
Thoracic Endovascular Aortic Repair (TEVAR) is the preferred treatment option for thoracic aortic pathologies and consists of inserting a...
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Development of a novel delivery quality assurance system based on simultaneous verification of dose distribution and binary multi-leaf collimator opening in helical tomotherapy
BackgroundIntensity-modulated radiation therapy (IMRT) requires delivery quality assurance (DQA) to ensure treatment accuracy and safety. Irradiation...
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Neuropathological Assessment as an Endpoint in Clinical Trial Design
Different neurodegenerative conditions can have complex, overlap** clinical presentations that make accurate diagnosis during life very...
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Job Possibilities in Clinical Research
Clinical research is a vital component when develo** new therapies for patients as it provides evidence that they are safe and effective. The...
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Survival-associated N6-adenosine methyltransferase signatures in lung squamous cell carcinoma and clinical verification
BackgroundN 6 -methyladenine (m 6 A) is the most common modification of mRNA and IncRNA in higher organisms. m 6 A has been confirmed to be related to the...
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Quality by Design in Relation to Clinical Trials
Clinical trials play a crucial role in evaluating the safety and efficacy of new drugs and treatments. Ensuring the quality and integrity of clinical...
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Clinical data mining: challenges, opportunities, and recommendations for translational applications
Clinical data mining of predictive models offers significant advantages for re-evaluating and leveraging large amounts of complex clinical real-world...
