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Circulating Tumor Cells Advances in Liquid Biopsy Technologies
It is well recognized that blood could be the optimal site for evaluating cancer, allowing easy and repeated access for determining prognosis,...
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Biophysical Properties and Isolation of Circulating Tumor Cells
Circulating tumor cells (CTCs) are tumor cells that have entered the bloodstream. Although the vast majority do not survive the numerous stressors in...
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Circulating Tumor Cells (CTC) and Tumor-Derived Extracellular Vesicles (tdEV)
The observation that increasing circulating tumor cell (CTC) and tumor-derived extracellular vesicle (tdEV) load is directly related to worse...
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Significance of circulating tumor cells detection in tumor diagnosis and monitoring
To detect circulating tumor cells (CTCs) in the peripheral blood of patients with tumor, and to analyze the significance of CTC detection in tumor...
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Circulating Tumor Cells in Men Treated for Prostate Cancer
Despite the advancements in prostate cancer treatments, a significant proportion of men with higher risk features (approximately 25-50%) ultimately...
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Capture and Selective Release of Viable Circulating Tumor Cells
Selectively capturing and releasing viable circulating tumor cells (CTCs) from the peripheral blood of cancer patients is advantageous for...
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Lateral Filter Array Microfluidic Devices for Detecting Circulating Tumor Cells
Circulating tumor cells (CTCs) are an important liquid biopsy biomarker for next-generation cancer diagnosis and prognosis. However, their clinical...
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Molecular Characterization of Single Circulating Tumor Cells in Breast and Ovarian Cancer
Epithelial ovarian cancer (EOC)Epithelial ovarian cancer (EOC) still has the highest mortality rate of all gynecological malignancies, diagnosed...
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Circulating Tumor Cells and ctDNA in Sarcomas
Sarcomas are clustered in two oncological entities named bone and soft tissue sarcomas. Both are rare cancers originating from the mesenchyme,...
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Isolating Circulating Cancer Stem Cells (CCSCs) from Human Whole Blood
Measuring circulating tumor cells (CTCs) or circulating cancer stem cells (CCSCs) in blood, which shed from primary tumors, is a noninvasive method...
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Clinical applications of circulating tumor cells in patients with solid tumors
The concept of liquid biopsy analysis has been established more than a decade ago. Since the establishment of the term, tremendous advances have been...
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Circulating Tumor Cells in Lung Cancer
The detection and identification of circulating tumor cells (CTCs) and the analysis of the information they provide are often the subject of...
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State of the Art in the Propagation of Circulating Tumor Cells
Circulating tumor cells (CTCs) are a group of cells that travel through the circulatory system of a cancer patient, sowing distant sites and forming...
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Diagnostic leukapheresis reveals distinct phenotypes of NSCLC circulating tumor cells
BackgroundCirculating tumor cells (CTCs) hold immense promise for unraveling tumor heterogeneity and understanding treatment resistance. However,...
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Survival mechanisms of circulating tumor cells and their implications for cancer treatment
Metastasis remains the principal trigger for relapse and mortality across diverse cancer types. Circulating tumor cells (CTCs), which originate from...
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Metabolic Reprogramming of Circulating Tumor Cells for Metastasis
Despite the leading cause of cancer-associated deaths, metastasis is a complex, multi-step, and inefficient biological process for cancer cells,...
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NGS-Based Tumor-Informed Analysis of Circulating Tumor DNA
Accurate circulating tumor DNA (ctDNA) detection has an immense biomarker potential in all phases of the cancer disease course. Presence of ctDNA in...
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A Microfluidic Approach for Enrichment and Single-Cell Characterization of Circulating Tumor Cells from Peripheral Blood
The emergence of enabling technologies for the analysis of circulating tumor cells has been shedding new lights into cancer management in the recent...
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Prostein expression on circulating tumor cells as a prognostic marker in metastatic castration-resistant prostate cancer
BackgroundIdentification of emerging molecular biomarkers on circulating tumor cells (CTCs) represents an attractive feature of liquid biopsy that...
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Clinical value of circulating tumor cells and hematological parameters in 617 Chinese patients with colorectal cancer: retrospective analysis
BackgroundCirculating tumor cells (CTCs) have been a non-invasive technique which allows investigation of tumor characteristics. The purpose of this...
