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Chemical Biology of Extracellular Vesicles
During the initial phases of extracellular vesicle (EV) research, researchers faced many obstacles, including a lack of standard methods for the...
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Microfluidics in Chemical Biology
Chemical biology is the field where two scientific disciplines, that is, chemistry and biology, join. Techniques derived from chemistry are used to...
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Functional genomics of human clear cell sarcoma: genomic, transcriptomic and chemical biology landscape for clear cell sarcoma
BackgroundSystemic therapy for metastatic clear cell sarcoma (CCS) bearing EWSR1-CREB1/ATF1 fusions remains an unmet clinical need in children,...
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Harnessing the necessary nitrogen atom in chemical biology and drug discovery
Despite 80 years of progress in modern small molecule drug discovery, medicinal chemists still struggle to minimize the number and duration of design...
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New Chemical Biology Tools for the Histamine Receptor Family
The histamine research community has in the last decade been very active and generated a number of exciting new chemical biology tools for the study...
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Chemical Carcinogens
This chapter is part of the Handbook of Cancer and Immunology, composed of various volumes addressing several aspects of different cancers, like...
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Forensic Biology
The field of forensic biology is an ever-evolving and constantly develo** field. It utilizes knowledge of biological concepts and practical...
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Multiplex protein imaging in tumour biology
Tissue imaging has become much more colourful in the past decade. Advances in both experimental and analytical methods now make it possible to image...
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Big data and deep learning for RNA biology
The exponential growth of big data in RNA biology (RB) has led to the development of deep learning (DL) models that have driven crucial discoveries....
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Molecular Biology of Arboviruses
This memoir traces the evolving studies on the molecular biology of arboviruses in the Strauss lab from 1969 to 2007. Jim began working with Sindbis...
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UCHL1 as a novel target in breast cancer: emerging insights from cell and chemical biology
Breast cancer has the highest incidence and death rate among cancers in women worldwide. In particular, metastatic estrogen receptor negative (ER–)...
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Systems Biology
Systems biology is an emerging approach to understand the holistic biology focussing on individual components of a biological system and their...
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Artificial Intelligence and Computational Biology in Gene Therapy: A Review
One of the trending fields in almost all areas of science and technology is artificial intelligence. Computational biology and artificial...
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Introduction to Extracellular Vesicles in Systems Biology
Extracellular vesicles (EVs) are fundamental small particles that act as molecular systems associated with physiological and disease states. The...
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Adapting modeling and simulation credibility standards to computational systems biology
Computational models are increasingly used in high-impact decision making in science, engineering, and medicine. The National Aeronautics and Space...
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Characterization of the CO release properties of a common CO donor, CORM-401, in the context of its application in studying CO biology
In studying CO for its pathophysiological roles, four metal/borane-carbonyl complexes have been widely used as CO-releasing molecules (CORMs) because...
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Vector Biology
Vectors transmit pathogens from one host individual to another. Most acquire pathogens by feeding on infected hosts, then transmit them by...
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Map** cancer biology in space: applications and perspectives on spatial omics for oncology
Technologies to decipher cellular biology, such as bulk sequencing technologies and single-cell sequencing technologies, have greatly assisted novel...
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Lipid in microglial biology — from material to mediator
Microglia are resident macrophages in the central nervous system (CNS) that play various roles during brain development and in the pathogenesis of...
