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Deep Learning for Perfusion Cerebral Blood Flow (CBF) and Volume (CBV) Predictions and Diagnostics
Dynamic susceptibility contrast magnetic resonance perfusion (DSC-MRP) is a non-invasive imaging technique for hemodynamic measurements. Various...
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Cerebral Perfusion Characteristics and Dynamic Brain Structural Changes in Stroke-Prone Renovascular Hypertensive Rats: A Preclinical Model for Cerebral Small Vessel Disease
Hypertension is a leading cause of cerebral small vessel disease (CSVD) and vascular dementia in elderly individuals. We aimed to assess cerebral...
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Arterial spin labeling reveals disordered cerebral perfusion and cerebral blood flow-based functional connectivity in primary open-angle glaucoma
PurposePrimary open-angle glaucoma (POAG) is a widespread neurodegenerative condition affecting brain regions involved in visual processing,...
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Assessment of Irreversible Tissue Injury in Extensive Ischemic Stroke—Potential of Quantitative Cerebral Perfusion
Computed tomography perfusion (CTP) is used as a tool to select ischemic stroke patients for endovascular treatment (EVT) and is currently...
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Effects of repetitive transcranial magnetic stimulation on improving cerebral blood flow in patients with middle cerebral artery steno-occlusion
BackgroundRepetitive transcranial magnetic stimulation (rTMS) has been reported to induce neurogenesis and angiogenesis. As increased neural activity...
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Synthetic role of miR-411-5p and CT perfusion information in predicting clinical outcomes after thrombolysis in acute cerebral infarction
BackgroundOur aim was to investigate the predictive value of microRNA (miR)-411-5p and computed tomography perfusion (CTP) parameters on the...
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The role of perfusion, grey matter volume and behavioural phenotypes in the data-driven classification of cognitive syndromes
BackgroundThe use of structural and perfusion brain imaging in combination with behavioural information in the prediction of cognitive syndromes...
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Quantitative transport map** of multi-delay arterial spin labeling MRI detects early blood perfusion alterations in Alzheimer’s disease
BackgroundQuantitative transport map** (QTM) of blood velocity, based on the transport equation has been demonstrated higher accuracy and...
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Increased cerebral vascular resistance underlies preserved cerebral blood flow in response to orthostasis in humans on a high-salt diet
Cerebral blood flow autoregulation protects brain tissue from blood pressure variations and maintains cerebral perfusion pressure by changes in...
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On the Sensitivity Analysis of Porous Finite Element Models for Cerebral Perfusion Estimation
Computational physiological models are promising tools to enhance the design of clinical trials and to assist in decision making. Organ-scale...
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Experimental carotid baroreceptor stimulation reduces blood flow velocities in the anterior and middle cerebral arteries of healthy individuals
This study investigated effects of experimental baroreceptor stimulation on bilateral blood flow velocities in the anterior and middle cerebral...
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Development and External Validation of Nomogram for Cerebral Infarction in Moyamoya Diseases
More than 60% of moyamoya disease (MMD) patients suffers cerebral ischemia and preoperative cerebral infarction (CI) increases the risk of...
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Quantification of Cerebral Vascular Autoregulation Immediately Following Resuscitation from Cardiac Arrest
Cerebral vascular autoregulation is impaired following resuscitation from cardiac arrest (CA), and its quantification may allow assessing CA-induced...
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Laser speckle contrast imaging for blood flow monitoring in predicting outcomes after cerebral ischemia-reperfusion injury in mice
BackgroundIn the treatment of ischemic cerebral stroke (ICS), most conventional treatments, including carotid endarterectomy and carotid artery...
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Minimally Invasive Intracerebral Hemorrhage Evacuation Improves Pericavity Cerebral Blood Volume
Cerebral blood volume map** can characterize hemodynamic changes within brain tissue, particularly after stroke. This study aims to quantify blood...
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Longitudinal alterations in brain perfusion and vascular reactivity in the zQ175DN mouse model of Huntington’s disease
BackgroundHuntington’s disease (HD) is marked by a CAG-repeat expansion in the huntingtin gene that causes neuronal dysfunction and loss, affecting...
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Cerebral Vasoreactivity
Cerebral blood flow is mainly regulated by two mechanisms: cerebral autoregulation and neurovascular coupling (NVC). Cerebral autoregulation... -
Cerebral tissue oximeter suitable for real-time regional oxygen saturation monitoring in multiple clinical settings
Maintenance of adequate blood perfusion and oxygen delivery is essential for cerebral metabolism. Cerebral oximeters based on near-infrared...
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Hypo- and hyper-perfusion in MCI and AD identified by different ASL MRI sequences
Arterial spin labeling (ASL) perfusion MRI has been increasingly used in Alzheimer's Disease (AD) research. However, ASL MRI sequences differ greatly...