Search
Search Results
-
Transient Receptor Potential Canonical (TRPC) as a Therapeutic Drug Target
Canonical or classical transient receptor potential (TRPC) proteins are nonselective cationic channels and a subset of TRP superfamily which are...
-
Calcium channel inhibitor and extracellular calcium improve aminoglycoside-induced hair cell loss in zebrafish
Aminoglycosides are commonly used antibiotics for treatment of gram-negative bacterial infections, however, they might act on inner ear, leading to...
-
CADENCE — Neuroinformatics Tool for Supervised Calcium Events Detection
CADENCE is an open Python 3-written neuroinformatics tool with Qt6 graphic user interface for supervised calcium events detection. In neuronal...
-
Sympathetic Nervous System Regulation of Cardiac Calcium Channels
Calcium influx through voltage-gated calcium channels, Cav1.2, in cardiomyocytes initiates excitation-contraction coupling in the heart. The force...
-
The importance of kidney calcium handling in the homeostasis of extracellular fluid calcium
Extracellular fluid calcium concentration must be maintained within a narrow range in order to sustain many biological functions, encompassing muscle...
-
Elevated Calcium after Acute Ischemic Stroke Predicts Severity and Prognosis
The aim of this study is to investigate whether there is a correlation between serum calcium levels and clinical severity or functional outcome at...
-
Emerging Roles of Sodium/Calcium Exchangers in Cancer
Cancer is a group of neoplastic diseases that shares as common feature uncontrolled cellular proliferation. Tumorigenesis and cancer progression are...
-
The T-type calcium channelosome
T-type calcium channels perform crucial physiological roles across a wide spectrum of tissues, spanning both neuronal and non-neuronal system. For...
-
Calcium Channels as a Potential Therapeutic Target for Alzheimer’s Disease
Alzheimer’s disease (AD) is the most common type of dementia that characterizes the accumulation of amyloid-β plaques and neurofibrillary tangles in...
-
Calcium imaging of adult olfactory epithelium reveals amines as important odor class in fish
The odor space of aquatic organisms is by necessity quite different from that of air-breathing animals. The recognized odor classes in teleost fish...
-
Transient Receptor Potential Channels: Multiple Modulators of Peripheral Neuropathic Pain in Several Rodent Models
Neuropathic pain, a prevalent chronic condition in clinical settings, has attracted widespread societal attention. This condition is characterized by...
-
Regulation of Presynaptic Calcium Channels
Voltage-gated calcium channels (VGCCs), especially Cav2.1 and Cav2.2, are the major mediators of Ca2+ influx at the presynaptic membrane in response...
-
Physiological functions of calcium signaling via Orai1 in cancer
Intracellular calcium (Ca 2+ ) signaling regulates many cellular functions, including cell proliferation and migration, in both normal cells and cancer...
-
The Role of Reactive Oxygen Species and Calcium Ions in Implementing the Stress-Protective Effect of γ-Aminobutyric Acid on Wheat Seedlings Under Heat Stress Conditions
γ-aminobutyric acid (GABA) is considered a molecule that combines the properties of a stress metabolite and a signaling molecule. At the same time,...
-
CaPTure: Calcium PeakToolbox for analysis of in vitro calcium imaging data
BackgroundCalcium imaging is a powerful technique for recording cellular activity across large populations of neurons. However, analysis methods...
-
Fiber photometry in striatum reflects primarily nonsomatic changes in calcium
Fiber photometry enables recording of population neuronal calcium dynamics in awake mice. While the popularity of fiber photometry has grown in...
-
Norepinephrine modulates calcium dynamics in cortical oligodendrocyte precursor cells promoting proliferation during arousal in mice
Oligodendrocytes, the myelinating cells of the central nervous system (CNS), are generated from oligodendrocyte precursor cells (OPCs) that express...
-
The Effects of Carvacrol on Transient Receptor Potential (TRP) Channels in an Animal Model of Parkinson’s Disease
In this study, we aimed to investigate the effects of carvacrol (CA), a widely used phytochemical having anti-oxidant and neuroprotective effects, on...
-
Cisplatin Provokes Peripheral Nociception and Neuronal Features of Therapy-Induced Senescence and Calcium Dysregulation in Rats
Therapy-Induced Senescence (TIS) is a form of senescence that is typically described in malignant cells in response to the exposure of cancer...
-
Transient Receptor Potential Vanilloid 6 Modulates Aberrant Axonal Sprouting in a Mouse Model of Pilocarpine-Induced Epilepsy
Transient receptor potential vanilloid 6 (TRPV6) is a highly selective calcium-ion channel that belongs to the TRPV family. TRPV6 is widely...
