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1. Blood–brain borders: a proposal to address limitations of historical blood–brain barrier terminology

   Many neuroscientists use the term Blood–Brain Barrier (BBB) to emphasize restrictiveness, often equating or reducing the notion of BBB properties to...

   Jerome Badaut, Jean-François Ghersi-Egea, ... Jan Pieter Konsman in Fluids and Barriers of the CNS

   Article Open access 05 January 2024
   

2. Blood-Brain Barrier

   in Dictionary of Toxicology

   Reference work entry 2024
   

3. Measurement of Transendothelial Electrical Resistance in Blood-Brain Barrier Endothelial Cells

   The integrity of the blood-brain barrier (BBB), the protective barrier of the brain, is key to maintaining normal microvascular permeability and...

   O’lisa Yaa Waithe, Xu Peng, ... Binu Tharakan in Vascular Hyperpermeability

   Protocol 2024
   

4. Determination of Blood-Brain Barrier Hyperpermeability Using Intravital Microscopy

   The blood vessels that vascularize the central nervous system (CNS) exhibit unique properties, termed the blood-brain barrier (BBB). The BBB allows...

   O’lisa Yaa Waithe, Chinchusha Anasooya Shaji, ... Binu Tharakan in Vascular Hyperpermeability

   Protocol 2024
   

5. Physiology, Pharmacology and Pathology of the Blood-Brain Barrier

   This book presents a comprehensive collection of current knowledge and leading research about the blood-brain barrier. The chapters are organized in...

   Zameel Cader, Winfried Neuhaus in Handbook of Experimental Pharmacology

   Book 2022
   

6. A pilot study to assess blood-brain barrier permeability in long COVID

   The etiology of brain fog associated with long COVID is not clear. Based on some preliminary work, disruption of the blood-brain barrier has been...

   Aditi Gupta, Branden Comfort, ... Robert Montgomery in Brain Imaging and Behavior

   Article 23 March 2024
   

7. Transporter Systems and Metabolism at the Blood–Brain Barrier and Blood–CSF Barrier

   Neurodegenerative disorders, including Alzheimer’s disease (AD), Parkinson’s disease (PD), and Huntington’s disease (HD), are a leading cause of...

   Kanika Verma, Devesh Kapoor, ... Swapnil Sharma in Drug Delivery Strategies in Neurological Disorders: Challenges and Opportunities

   Chapter 2023
   

8. Blood-Brain Barrier

   While Edwin Goldmann is recognized as the first to provide substantial evidence of a blood-brain barrier (BBB) in 1909 and 1913, the actual term was...

   B. Martin, R. Leshan, ... M. Souweidane in Neuroscience in the 21st Century

   Living reference work entry 2022
   

9. Blood-Brain Barrier

   While Edwin Goldmann is recognized as the first to provide substantial evidence of a blood-brain barrier (BBB) in 1909 and 1913, the actual term was...

   B. Martin, R. Leshan, ... M. Souweidane in Neuroscience in the 21st Century

   Reference work entry 2022
   

10. SARS-CoV-2 infects epithelial cells of the blood-cerebrospinal fluid barrier rather than endothelial cells or pericytes of the blood-brain barrier

    Background

    As a consequence of SARS-CoV-2 infection various neurocognitive and neuropsychiatric symptoms can appear, which may persist for several...

    Chiara Stüdle, Hideaki Nishihara, ... Britta Engelhardt in Fluids and Barriers of the CNS

    Article Open access 24 October 2023
    

11. Receptor-Assisted Nanotherapeutics for Overcoming the Blood–Brain Barrier

    Blood–brain barrier (BBB) is a distinguishing checkpoint that segregates peripheral organs from neural compartment. It protects the central nervous...

    Akshada Mhaske, Shalini Shukla, ... Rahul Shukla in Molecular Neurobiology

    Article Open access 01 April 2024
    

12. Proteasome inhibition protects blood–brain barrier P-glycoprotein and lowers Aβ brain levels in an Alzheimer’s disease model

    Background

    Loss of P-glycoprotein (P-gp) at the blood–brain barrier contributes to amyloid-β (Aβ) brain accumulation in Alzheimer’s disease (AD)....

    Milica Vulin, Yu Zhong, ... Anika M. S. Hartz in Fluids and Barriers of the CNS

    Article Open access 06 October 2023
    

13. Evaluation of Barrier Integrity Using a Two-Layered Microfluidic Device Mimicking the Blood-Brain Barrier

    The blood-brain barrier (BBB) plays an essential role in maintaining the homeostasis of the brain microenvironment by controlling the influx and...

    Hossam Kadry, Luca Cucullo in Vascular Hyperpermeability

    Protocol 2024
    

14. Breaking barriers: exploring mechanisms behind opening the blood–brain barrier

    The blood–brain barrier (BBB) is a selectively permeable membrane that separates the bloodstream from the brain. While useful for protecting neural...

    Melanie E. M. Stamp, Michael Halwes, ... David J. Collins in Fluids and Barriers of the CNS

    Article Open access 28 November 2023
    

15. Exosomes: Promising Delivery Tools for Overcoming Blood-Brain Barrier and Glioblastoma Therapy

    Gliomas make up virtually 80% of all lethal primary brain tumors and are categorized based on their cell of origin. Glioblastoma is an astrocytic...

    Seyyed Hossein Khatami, Neda Karami, ... Ahmad Movahedpour in Molecular Neurobiology

    Article 03 May 2023
    

16. Measurement of Blood-Brain Barrier Hyperpermeability Using Evans Blue Extravasation Assay

    Blood-brain barrier (BBB) dysfunction and hyperpermeability have been implicated in a myriad of brain pathologies. The Evans Blue assay is one of the...

    O’lisa Yaa Waithe, Xu Peng, ... Binu Tharakan in Vascular Hyperpermeability

    Protocol 2024
    

17. Andrographolide Improves ApoE4-Mediated Blood–Brain Barrier Injury by Alleviating Inflammation

    The pathological and physiological studies of Alzheimer’s disease (AD) have been in-depth, and apolipoprotein E4 (ApoE4) has been proven to be highly...

    Xuebin Zhou, **hua Li, ... Qin Li in Molecular Neurobiology

    Article 06 March 2024
    

18. Active Uptake of Oxycodone at Both the Blood-Cerebrospinal Fluid Barrier and The Blood-Brain Barrier without Sex Differences: A Rat Microdialysis Study

    Background

    Oxycodone active uptake across the blood-brain barrier (BBB) is associated with the putative proton-coupled organic cation (H ⁺ /OC)...

    Frida Bällgren, Margareta Hammarlund-Udenaes, Irena Loryan in Pharmaceutical Research

    Article Open access 23 August 2023
    

19. Hypoxic oligodendrocyte precursor cell-derived VEGFA is associated with blood–brain barrier impairment

    Cerebral small vessel disease is characterised by decreased cerebral blood flow and blood–brain barrier impairments which play a key role in the...

    Narek Manukjan, Daria Majcher, ... Sébastien Foulquier in Acta Neuropathologica Communications

    Article Open access 07 August 2023
    

20. Ischemia Reperfusion Injury Induced Blood Brain Barrier Dysfunction and the Involved Molecular Mechanism

    Stroke is characterized by the abrupt failure of blood flow to a specific brain region, resulting in insufficient supply of oxygen and glucose to the...

    ** Wu in Neurochemical Research

    Article 05 April 2023