Search
Search Results
-
Small-molecule discovery through DNA-encoded libraries
The development of bioactive small molecules as probes or drug candidates requires discovery platforms that enable access to chemical diversity and...
-
Fungal Endophytes: An Accessible Natural Repository for Discovery of Bioactive Compounds
Microorganisms are proficient synthesizers of natural product molecules that are often bioactive and a source of various antibiotics and other...
-
Marine Peptides and Their Bioactive Potentials: New Horizon for Biotherapeutics
Marine ecosystems act as a reservoir of innumerable novel bioactive compounds by instigating stressful environments. Thus, marine bio-resources have...
-
Targeting of wnt signalling pathway by small bioactive molecules for the treatment of Alzheimer’s disease
Alzheimer’s disease (AD) is the most occurring neurodegenerative disorder that destroys learning, memory, and thinking skills. Although the...
-
Endolichenic Fungi, an Emerging Source of Bioactive Compounds: A Pharmaceutical Perspective
Endolichenic fungi (ELF), residing within the thallus of lichen, which is a symbiotic association of algae and fungi, are emerging as an alternative...
-
Natural Bioactive Products from Marine Fungi Against Bacterial Infection
In spite of the different antibiotics available in the market, the need for new antibacterial agents is still in high demand. This is because of...
-
Structural analysis and prediction of potent bioactive molecule for eNOS protein through molecular docking
Reactive oxygen species by uncoupled eNOS is linked to endothelial dysfunction. Ellagic acid (EA), a polyphenol possesses numerous biological...
-
Chromatographic Methods for Separation and Identification of Bioactive Compounds
Chromatographic methods are widely used in the separation and identification of bioactive compounds in complex samples. Chromatography is a technique...
-
Marine Bioactive Compounds: An Alternative to Antibiotics
Antimicrobial resistance (AMR) remains as a critical concern of modern medicine today. Medical practitioners face difficulty in treating various...
-
Marine Bioactive Compounds, An Alternative to Antibiotics
Antimicrobial resistance (AMR) remains as a critical concern of modern medicine today. Medical practitioners face difficulty in treating various...
-
Potentiality of bioactive compounds as inhibitor of M protein and F protein function of human respiratory syncytial virus
The human respiratory syncytial virus (RSV) creates a pandemic every year in several countries in the world. Lack of target therapeutics and absence...
-
Challenges and Future Perspectives of Using Bioactive Scaffolds in Brain Repair
Introduction: Scientific and technological developments have allowed the transfer of knowledge to the translational vision of materials, under an...
-
Myricetin: a potential plant-derived anticancer bioactive compound—an updated overview
The globe is currently confronting a global fight against the deadliest cancer sickness. Chemotherapy, hormonal therapy, surgery, and radiation...
-
Identification of bioactive compounds from Vaccinium vitis-idaea L. (Lingonberry) as inhibitors for treating KRAS-associated cancer: a computational approach
Lung cancer is the cancer of the lung’s epithelial cells typically characterized by difficulty breathing, chest pain, blood-stained coughs, headache,...
-
Bioactive Metabolites Produced by Fungi Present in Antarctic, Arctic, and Alpine Ecosystems
Hostile and harsh environments to most organisms represent more than 80% of the earth’s surface. These extreme environments shelter interesting...
-
Alzheimer’s disease: using gene/protein network machine learning for molecule discovery in olive oil
Alzheimer’s disease (AD) poses a profound human, social, and economic burden. Previous studies suggest that extra virgin olive oil (EVOO) may be...
-
Plant-Derived Bioactive Compounds as Potential ACE-2 Inhibitors Against SARS-CoV-2 Infection
Severe acute respiratory syndrome coronavirus 2 (SARS-COV-2) resulted in the COVID-19 pandemic associated with severe morbidity, high mortality and...
-
Bioactive potential and chemical characterization of Planaxis sulcatus (Phylum: Mollusca, Family: Planaxidae) solvent extracts
The world urgently needs to discover new drugs to meet the challenges that threaten human health. Marine molluscs are known as natural sources of...
-
Bioactive Metabolites from Fungi with Anti-Inflammatory and Antithrombotic Properties: Current Status and Future Perspectives for Drug Development
Bioactives of natural origin have recently gained a lot of ground in drug discovery due to their enormous structural diversity, diverse...
-
Insights into In Silico Methods to Explore Plant Bioactive Substances in Combating SARS-CoV-2
SARS-CoV-2 is a virus belonging to the species “severe acute respiratory syndrome-related coronavirus” (SARSr-CoV), a strain that causes the...